prasterone sulfate Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
androgens/anabolic steroids 4049 651-48-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • prasterone sulfate
  • dehydroandrosterone sulfate
  • dehydroepiandrosterone monosulfate
  • dehydroepiandrosterone sulfate
  • dehydroepiandrosterone sulphate
  • dehydroisoandrosterone sulfate
The circulating form of a major C19 steroid produced primarily by the ADRENAL CORTEX. DHEA sulfate serves as a precursor for TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE.
  • Molecular weight: 368.49
  • Formula: C19H28O5S
  • CLOGP: 3.01
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 80.67
  • ALOGS: -4.66
  • ROTB: 2

  • Status: ONP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:75771 Mus musculus metabolite
CHEBI has role CHEBI:77194 pantothenate kinase (phosphorylating) inhibitors
CHEBI has role CHEBI:77746 H. sapiens metabolites
CHEBI has role CHEBI:50113 androgens

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 0.53 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4021360 VANDF
4036745 VANDF
C0057277 UMLSCUI
CHEBI:16814 CHEBI
CHEBI:28689 CHEBI
DB05804 DRUGBANK_ID
12594 PUBCHEM_CID
4528 IUPHAR_LIGAND_ID
2869 INN_ID
57B09Q7FJR UNII
5881 PUBCHEM_CID
DB01708 DRUGBANK_ID
3143 RXNORM
131731 MMSL
20676 MMSL
32118 MMSL
73034 MMSL
d04425 MMSL
004609 NDDF
103044003 SNOMEDCT_US
413963008 SNOMEDCT_US
78316004 SNOMEDCT_US
D019314 MESH_DESCRIPTOR_UI
C0011185 UMLSCUI

Pharmaceutical products:

None