benzamycin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
antibiotics, produced by Streptomyces strains	3875	376597-09-0

Description:

Molecule

Description

Synonyms:

benzamycin
Benzoyl peroxide-erythromyxin mixt.

Molecular weight: 976.17
Formula: C51H77NO17
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Acne vulgaris	indication	88616000
Erythroderma	contraindication	399992009
Inflammatory dermatosis	contraindication	703938007

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Potassium voltage-gated channel subfamily H member 2	Ion channel	Q12809	KCNH2_HUMAN		IC50	7.41		CHEMBL
Aldehyde oxidase	Enzyme	Q06278	AOXA_HUMAN		IC50	4.01		CHEMBL
Motilin receptor	GPCR	O43193	MTLR_HUMAN		IC50	7.36		CHEMBL
Cytochrome P450 1B1	Enzyme	Q16678	CP1B1_HUMAN		IC50	4.40		CHEMBL

External reference:

ID	Source
C0385222	UMLSCUI
CHEMBL1200370	ChEMBL_ID
CHEMBL532	ChEMBL_ID
C097386	MESH_SUPPLEMENTAL_RECORD_UI
12560	PUBCHEM_CID
117919	RXNORM
185	MMSL

Pharmaceutical products:

None