alprostadil alfadex 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
prostaglandins 3864 55648-20-9

Description:

MoleculeDescription

Synonyms:

  • alprostadil alfadex
  • tandetoron
  • Molecular weight: 1327.33
  • Formula: C56H94O35
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

PropertyValueReference
MRTD (Maximum Recommended Therapeutic Daily Dose) 0.01 µM/kg/day Contrera JF, Matthews EJ, Kruhlak NL, Benz RD

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA CS M0017805 Prostaglandins
FDA MoA N0000000106 Prostaglandin Receptor Agonists
FDA PE N0000009059 Genitourinary Arterial Vasodilation
FDA PE N0000009911 Venous Vasodilation
FDA EPC N0000175454 Prostaglandin Analog
MeSH PA D002317 Cardiovascular Agents
MeSH PA D006401 Hematologic Agents
MeSH PA D010975 Platelet Aggregation Inhibitors
MeSH PA D064804 Urological Agents
MeSH PA D014665 Vasodilator Agents
CHEBI has role CHEBI:35620 vasodilator agents
CHEBI has role CHEBI:50249 anticoagulants
CHEBI has role CHEBI:50427 platelet aggregation inhibitors
CHEBI has role CHEBI:77746 Homo sapiens metabolite
FDA EPC N0000180189 Prostaglandin E1 Agonist

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02705 KEGG_DRUG
4018099 VANDF
CHEBI:34532 CHEBI
CHEBI:15544 CHEBI
CHEMBL2108900 ChEMBL_ID
5282234 PUBCHEM_CID
598 RXNORM
11600 MMSL
4154 MMSL
d01387 MMSL
000704 NDDF
109119001 SNOMEDCT_US
48988008 SNOMEDCT_US
C0002335 UMLSCUI
DB00770 DRUGBANK_ID
4425 INN_ID
D000527 MESH_DESCRIPTOR_UI
5280723 PUBCHEM_CID

Pharmaceutical products:

None