bisaramil 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
calcium channel blockers, verapamil derivatives 377 89194-77-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bisaramil
  • alpha-Yutac
  • Molecular weight: 322.83
  • Formula: C17H23ClN2O2
  • CLOGP: 2.14
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 0
  • TPSA: 32.78
  • ALOGS: -2.60
  • ROTB: 4

Drug dosage:

None

ADMET properties:

PropertyValueReference
Vd (Volume of distribution) 9 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 17 mL/min/kg Lombardo F, Berellini G, Obach RS
t_half (Half-life) 8.60 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.99 Basic
pKa2 6.94 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0106533 UMLSCUI
CHEBI:135371 CHEBI
CHEMBL4297144 ChEMBL_ID
CHEMBL2103780 ChEMBL_ID
C045644 MESH_SUPPLEMENTAL_RECORD_UI
3033742 PUBCHEM_CID
6326 INN_ID
FVT2ESG270 UNII

Pharmaceutical products:

None