ciramadol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
analgesics 3713 63269-31-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ciramadol
  • ciramadol hydrochloride
  • WY15705
  • WY-15705
  • ciramadol HCl
benzylamine analgesics; structure given in fourth source
  • Molecular weight: 249.35
  • Formula: C15H23NO2
  • CLOGP: 2.38
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 2
  • TPSA: 43.70
  • ALOGS: -1.97
  • ROTB: 3

Drug dosage:

None

ADMET properties:

PropertyValueReference
CL (Clearance) 2.20 mL/min/kg Lombardo F, Berellini G, Obach RS
t_half (Half-life) 3.85 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000700 Analgesics
MeSH PA D002491 Central Nervous System Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.47 acidic
pKa2 7.9 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Mu-type opioid receptor GPCR MODULATOR SCIENTIFIC LITERATURE SCIENTIFIC LITERATURE

External reference:

IDSource
D03523 KEGG_DRUG
C0055779 UMLSCUI
CHEBI:135016 CHEBI
CHEMBL2104132 ChEMBL_ID
C018273 MESH_SUPPLEMENTAL_RECORD_UI
44463 PUBCHEM_CID
4464 INN_ID
63323-46-6 SECONDARY_CAS_RN
9NQ109OW0G UNII
CHEMBL2104041 ChEMBL_ID

Pharmaceutical products:

None