trapidil 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| vasodilators | 3621 | 15421-84-8 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A coronary vasodilator agent.
|
Drug dosage:
None
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| BA (Bioavailability) | 96 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | C01DX11 | CARDIOVASCULAR SYSTEM CARDIAC THERAPY VASODILATORS USED IN CARDIAC DISEASES Other vasodilators used in cardiac diseases |
| MeSH PA | D002317 | Cardiovascular Agents |
| MeSH PA | D004791 | Enzyme Inhibitors |
| MeSH PA | D006401 | Hematologic Agents |
| MeSH PA | D010726 | Phosphodiesterase Inhibitors |
| MeSH PA | D010975 | Platelet Aggregation Inhibitors |
| MeSH PA | D014665 | Vasodilator Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 4.35 | Basic |
| pKa2 | 1.34 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| N0000167188 | NUI |
| D01220 | KEGG_DRUG |
| C0040779 | UMLSCUI |
| CHEBI:32254 | CHEBI |
| K1S | PDB_CHEM_ID |
| CHEMBL132767 | ChEMBL_ID |
| DB09283 | DRUGBANK_ID |
| D014192 | MESH_DESCRIPTOR_UI |
| 5531 | PUBCHEM_CID |
| 3402 | INN_ID |
| EYG5Y6355E | UNII |
| 10735 | RXNORM |
| 007041 | NDDF |
Pharmaceutical products:
None