roquinimex 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| immunostimulants | 3532 | 84088-42-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Bocci G, Oprea TI, Benet LZ |
| BA (Bioavailability) | 99 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
| Vd (Volume of distribution) | 0.21 L/kg | Lombardo F, Berellini G, Obach RS |
| CL (Clearance) | 0.08 mL/min/kg | Lombardo F, Berellini G, Obach RS |
| t_half (Half-life) | 31 hours | Lombardo F, Berellini G, Obach RS |
| S (Water solubility) | 0.20 mg/mL | Bocci G, Oprea TI, Benet LZ |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | L03AX02 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS IMMUNOSTIMULANTS IMMUNOSTIMULANTS Other immunostimulants |
| MeSH PA | D000276 | Adjuvants, Immunologic |
| MeSH PA | D020533 | Angiogenesis Inhibitors |
| MeSH PA | D000970 | Antineoplastic Agents |
| MeSH PA | D006131 | Growth Inhibitors |
| MeSH PA | D006133 | Growth Substances |
| MeSH PA | D007155 | Immunologic Factors |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.61 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D05756 | KEGG_DRUG |
| C0244748 | UMLSCUI |
| CHEBI:92056 | CHEBI |
| CHEMBL11672 | ChEMBL_ID |
| DB11366 | DRUGBANK_ID |
| C045282 | MESH_SUPPLEMENTAL_RECORD_UI |
| 54676478 | PUBCHEM_CID |
| 5726 | INN_ID |
| 372T2944C0 | UNII |
Pharmaceutical products:
None