prednival 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3488 15180-00-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • prednival
  • prednisolone 17-valerate
  • Molecular weight: 444.57
  • Formula: C26H36O6
  • CLOGP: 3.55
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 2
  • TPSA: 100.90
  • ALOGS: -4.56
  • ROTB: 7

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
S (Water solubility) 0.22 mg/mL Bocci G, Oprea TI, Benet LZ

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA MoA N0000175450 Corticosteroid Hormone Receptor Agonists
FDA EPC N0000175576 Corticosteroid
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D018931 Antineoplastic Agents, Hormonal
MeSH PA D005938 Glucocorticoids
MeSH PA D006728 Hormones
CHEBI has role CHEBI:35472 anti-inflammatory drugs
CHEBI has role CHEBI:35610 antineoplastic agents
CHEBI has role CHEBI:35703 Xenobiotic
CHEBI has role CHEBI:35705 immunosuppressive agents
CHEBI has role CHEBI:37962 adrenergic agents
CHEBI has role CHEBI:49103 drug metabolites
CHEBI has role CHEBI:78298 environmental contaminants

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.48 acidic
pKa2 13.19 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D05603 KEGG_DRUG
4017988 VANDF
C2698873 UMLSCUI
CHEBI:135723 CHEBI
CHEBI:8378 CHEBI
TUA PDB_CHEM_ID
CHEMBL2104719 ChEMBL_ID
3NJ3X78O0C UNII
9824723 PUBCHEM_CID
DB00860 DRUGBANK_ID
8638 RXNORM
5347 MMSL
59710 MMSL
d00084 MMSL
002155 NDDF
116601002 SNOMEDCT_US
52388000 SNOMEDCT_US
C0032950 UMLSCUI
535 INN_ID
5755 PUBCHEM_CID
D011239 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None