phenolsulfonphthalein 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
3439 143-74-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • phenolsulfonphthalein
  • fenolipuna
  • phenol red
  • phenolsulfonephthalein
  • phenolsulphonphthalein
  • sulfonphthal
  • sulphental
  • sulphonthal
Red dye, pH indicator, and diagnostic aid for determination of renal function. It is used also for studies of the gastrointestinal and other systems.
  • Molecular weight: 354.38
  • Formula: C19H14O5S
  • CLOGP: 2.38
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 83.83
  • ALOGS: -4.29
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AURKA,AXL,BRAF,BTK,CAMK2D,CDK5,CDK9,DYRK1B,EIF2AK3,ERBB2,GRK2,ITK,MAP2K6,MAP3K7,MAPK10,MAPK7,MAPKAPK2,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PIK3CG,PIM2,PRKDC,STK33,TEK,TGFBR1 30
kinase-selectivity-class ACVR2A,ACVR2B,AXL,DYRK1B,GRK2,MAP2K6,MAPK7,RIPK1,SIK2,TEK 10
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V04CH03 VARIOUS
DIAGNOSTIC AGENTS
OTHER DIAGNOSTIC AGENTS
Tests for renal function and ureteral injuries
MeSH PA D004396 Coloring Agents
MeSH PA D007202 Indicators and Reagents
CHEBI has role CHEBI:33295 diagnostic agent
CHEBI has role CHEBI:50407 acid-base indicator
CHEBI has role CHEBI:50412 two-colour indicator

Related Drugs by ATC class:

V04CH Tests for renal function and ureteral injuries 4 drugs
alsactideaminohippuric acidindigo carmineinulin

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Renal function study indication 44277000




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.39 acidic
pKa2 7.99 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4018105 VUID
N0000146443 NUI
D01200 KEGG_DRUG
4018105 VANDF
C0031430 UMLSCUI
CHEBI:31991 CHEBI
CHEMBL258921 ChEMBL_ID
DB13212 DRUGBANK_ID
D010637 MESH_DESCRIPTOR_UI
4766 PUBCHEM_CID
I6G9Y0J1OJ UNII
8141 RXNORM
002339 NDDF

Pharmaceutical products:

None