Stem definition | Drug id | CAS RN |
---|---|---|
quinoline derivatives | 3413 | 485-89-2 |
Dose | Unit | Route |
---|---|---|
1.50 | g | O |
None
None
None
None
None
None
Source | Code | Description |
---|---|---|
ATC | M01CA03 | MUSCULO-SKELETAL SYSTEM ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS SPECIFIC ANTIRHEUMATIC AGENTS Quinolines |
None
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 1.4 | acidic |
pKa2 | 10.86 | acidic |
pKa3 | 3.88 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial | Enzyme | IC50 | 4.92 | CHEMBL | |||||
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Enzyme | Kd | 4.82 | CHEMBL |
ID | Source |
---|---|
D07271 | KEGG_DRUG |
C1882245 | UMLSCUI |
CHEBI:135094 | CHEBI |
CHEMBL219376 | ChEMBL_ID |
DB13596 | DRUGBANK_ID |
10239 | PUBCHEM_CID |
489 | INN_ID |
UK6392GD5W | UNII |
None