oxycinchophen 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
quinoline derivatives 3413 485-89-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oxycinchophen
  • chinoxone
  • fenidrone
  • hydroxycinchophene
  • oxinofen
  • Molecular weight: 265.27
  • Formula: C16H11NO3
  • CLOGP: 4.95
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 2
  • TPSA: 70.42
  • ALOGS: -3.49
  • ROTB: 2

Drug dosage:

DoseUnitRoute
1.50 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M01CA03 MUSCULO-SKELETAL SYSTEM
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
SPECIFIC ANTIRHEUMATIC AGENTS
Quinolines

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 1.4 acidic
pKa2 10.86 acidic
pKa3 3.88 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Dihydroorotate dehydrogenase (quinone), mitochondrial Enzyme IC50 4.92 CHEMBL
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Enzyme Kd 4.82 CHEMBL

External reference:

IDSource
D07271 KEGG_DRUG
C1882245 UMLSCUI
CHEBI:135094 CHEBI
CHEMBL219376 ChEMBL_ID
DB13596 DRUGBANK_ID
10239 PUBCHEM_CID
489 INN_ID
UK6392GD5W UNII

Pharmaceutical products:

None