ornithine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3401 70-26-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ornithine
  • L-Ornithine
  • (S)-2,5-Diaminopentanoic acid
  • (S)-Ornithine
An amino acid produced in the urea cycle by the splitting off of urea from arginine.
  • Molecular weight: 132.16
  • Formula: C5H12N2O2
  • CLOGP: -2.84
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 3
  • TPSA: 89.34
  • ALOGS: 0.11
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Female Facial Hirsutism indication
Eruption of skin contraindication 271807003 DOID:0050486
Skin irritation contraindication 367466007

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 1.85 acidic
pKa2 10.19 Basic
pKa3 9.23 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
G-protein coupled receptor family C group 6 member A GPCR AGONIST EC50 4 IUPHAR

External reference:

IDSource
N0000006781 NUI
C0029277 UMLSCUI
D08302 KEGG_DRUG
8514004 SNOMEDCT_US
7704 RXNORM
003541 NDDF
6262 PUBCHEM_CID
CHEBI:18257 CHEBI
CHEMBL446143 ChEMBL_ID
DB00129 DRUGBANK_ID
E524N2IXA3 UNII
6167 INN_ID
ORN PDB_CHEM_ID
D009952 MESH_DESCRIPTOR_UI
725 IUPHAR_LIGAND_ID

Pharmaceutical products:

None