oleandrin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3399 465-16-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oleandrin
  • corrigen
  • foliandrin
  • folinerin
  • neriostene
  • oleandrine
  • Molecular weight: 576.73
  • Formula: C32H48O9
  • CLOGP: 2.85
  • LIPINSKI: 1
  • HAC: 9
  • HDO: 2
  • TPSA: 120.75
  • ALOGS: -5.28
  • ROTB: 6

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Neurogenic locus notch homolog protein 1 Unclassified IC50 6.92 CHEMBL

External reference:

IDSource
C0069397 UMLSCUI
CHEBI:59030 CHEBI
CHEMBL4285883 ChEMBL_ID
CHEMBL1075789 ChEMBL_ID
DB12843 DRUGBANK_ID
C021065 MESH_SUPPLEMENTAL_RECORD_UI
12618 IUPHAR_LIGAND_ID
II95UDU7I4 UNII
11541511 PUBCHEM_CID
35871001 SNOMEDCT_US

Pharmaceutical products:

None