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| Stem definition | Drug id | CAS RN |
|---|---|---|
| 334 | 100-51-6 |
None
None
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,ITK,JAK1,JAK2,MAP3K21,MAP3K7,MAPK7,MAPK9,MTOR,NTRK2,PDK2,PDK4,PIK3CB,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,TEK,TTK,ULK1 | 38 | |||
| kinase-selectivity-class | ACVR2A,ACVR2B,AXL,BRAF,EPHB4,ERBB2,GRK2,PDK4,SIK2,SIK3 | 10 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
| Date | Agency | Company | Orphan |
|---|---|---|---|
| April 9, 2009 | FDA | SHIONOGI INC |
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None
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None
| Source | Code | Description |
|---|---|---|
| ATC | P03AX06 | ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS ECTOPARASITICIDES, INCL. SCABICIDES Other ectoparasiticides, incl. scabicides |
| FDA EPC | N0000181811 | Pediculicide |
| CHEBI has role | CHEBI:22586 | antioxidant |
| CHEBI has role | CHEBI:25212 | metabolite |
| CHEBI has role | CHEBI:35442 | antiparasitic agent |
| CHEBI has role | CHEBI:46787 | solvent |
| CHEBI has role | CHEBI:48318 | fragrance |
| MeSH PA | D000777 | Anesthetics |
| MeSH PA | D000779 | Anesthetics, Local |
| MeSH PA | D002492 | Central Nervous System Depressants |
| MeSH PA | D018689 | Sensory System Agents |
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Skin irritation | indication | 367466007 | |
| Itching of skin | indication | 418363000 | |
| Peptic ulcer | contraindication | 13200003 | DOID:750 |
| Chronic obstructive lung disease | contraindication | 13645005 | DOID:3083 |
| Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
| Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
| Contact dermatitis | contraindication | 40275004 | DOID:2773 |
| Coronary arteriosclerosis | contraindication | 53741008 | DOID:3393 |
| Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
| Chronic idiopathic constipation | contraindication | 82934008 | |
| Open wound | contraindication | 125643001 | |
| Gastrointestinal obstruction | contraindication | 126765001 | |
| Bladder outflow obstruction | contraindication | 236645006 | |
| Benign prostatic hyperplasia | contraindication | 266569009 | |
| Retention of urine | contraindication | 267064002 | |
| Angle-closure glaucoma | contraindication | 392291006 | DOID:13550 |
| Hypertensive urgency | contraindication | 443482000 |
None
None
None
None
None
None
| ID | Source |
|---|---|
| LKG8494WBH | UNII |
| 4017798 | VUID |
| N0000146159 | NUI |
| D00077 | KEGG_DRUG |
| 1426 | RXNORM |
| C0005100 | UMLSCUI |
| CHEBI:17987 | CHEBI |
| 010 | PDB_CHEM_ID |
| CHEMBL720 | ChEMBL_ID |
| 244 | PUBCHEM_CID |
| DB06770 | DRUGBANK_ID |
| D019905 | MESH_DESCRIPTOR_UI |
| 923 | INN_ID |
| 11807 | MMSL |
| NOCODE | MMSL |
| 4017445 | VANDF |
| 4017798 | VANDF |
| 003192 | NDDF |
| 400850005 | SNOMEDCT_US |
| 55902002 | SNOMEDCT_US |
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| ITCH X | HUMAN OTC DRUG LABEL | 2 | 0225-0495 | GEL | 10 g | TOPICAL | OTC Monograph Drug | 14 sections |
| ITCH-X | HUMAN OTC DRUG LABEL | 2 | 0225-0516 | SPRAY | 10 g | TOPICAL | OTC monograph not final | 13 sections |
| Walgreens Unscented Pain Relieving | HUMAN OTC DRUG LABEL | 2 | 0363-6752 | CREAM | 100 mg | TOPICAL | OTC Monograph Drug | 14 sections |
| Walgreens Lidocaine Plus Cream | HUMAN OTC DRUG LABEL | 2 | 0363-9951 | CREAM | 100 mg | TOPICAL | OTC Monograph Drug | 14 sections |
| Ivarest | HUMAN OTC DRUG LABEL | 3 | 10157-9077 | CREAM | 10.50 g | TOPICAL | OTC Monograph Drug | 14 sections |
| Orajel Toothache Rinse | HUMAN OTC DRUG LABEL | 2 | 10237-764 | LIQUID | 2.70 mg | TOPICAL | OTC Monograph Drug | 11 sections |
| Nitrotan | HUMAN OTC DRUG LABEL | 4 | 11960-0049 | AEROSOL, SPRAY | 0.06 g | TOPICAL | OTC monograph not final | 9 sections |
| Cipro HC | HUMAN PRESCRIPTION DRUG LABEL | 3 | 16590-053 | SUSPENSION | 9 mg | AURICULAR (OTIC) | NDA | 9 sections |
| ZilactinEarly Relief Cold Sore | HUMAN OTC DRUG LABEL | 1 | 42829-468 | GEL | 0.10 g | TOPICAL | OTC Monograph Drug | 10 sections |
| Ivy-Dry Super | HUMAN OTC DRUG LABEL | 3 | 49546-105 | SPRAY | 100 mg | TOPICAL | OTC monograph not final | 13 sections |
| Ivy-Dry Super | HUMAN OTC DRUG LABEL | 3 | 49546-106 | SPRAY | 100 mg | TOPICAL | OTC monograph not final | 13 sections |
| Ivy Dry | HUMAN OTC DRUG LABEL | 3 | 49546-201 | CREAM | 10 g | TOPICAL | OTC monograph not final | 14 sections |
| Lidocaine Plus Pain Relieving | HUMAN OTC DRUG LABEL | 2 | 51316-175 | LIQUID | 100 mg | TOPICAL | OTC Monograph Drug | 13 sections |
| AVERTEAX | HUMAN OTC DRUG LABEL | 1 | 54866-002 | CREAM | 10 mg | TOPICAL | OTC monograph not final | 11 sections |
| Cipro | HUMAN PRESCRIPTION DRUG LABEL | 3 | 54868-4365 | SUSPENSION | 9 mg | AURICULAR (OTIC) | NDA | 10 sections |
| Salonpas LIDOCAINE PLUS | HUMAN OTC DRUG LABEL | 2 | 55328-901 | LIQUID | 10 g | TOPICAL | OTC Monograph Drug | 15 sections |
| Salonpas LIDOCAINE PLUS | HUMAN OTC DRUG LABEL | 2 | 55328-902 | CREAM | 10 g | TOPICAL | OTC Monograph Drug | 14 sections |
| shing-Releev | HUMAN OTC DRUG LABEL | 3 | 63287-420 | LIQUID | 5 mg | TOPICAL | OTC monograph not final | 8 sections |
| Fast Freeze Lidocaine Roll-On | HUMAN OTC DRUG LABEL | 2 | 66902-235 | LIQUID | 10 mg | TOPICAL | OTC Monograph Drug | 14 sections |
| CVS Health Lidocaine PlusPain Relieving | HUMAN OTC DRUG LABEL | 2 | 66902-758 | CREAM | 100 mg | TOPICAL | OTC Monograph Drug | 13 sections |
| Pain Relieving Cream Lidocaine | HUMAN OTC DRUG LABEL | 2 | 69396-139 | CREAM | 10 g | TOPICAL | OTC Monograph Drug | 14 sections |
| Thermacare Heat Therapy Max Strength Lidocaine Pain Relief Rollon | HUMAN OTC DRUG LABEL | 2 | 69693-002 | LIQUID | 10 g | TOPICAL | OTC Monograph Drug | 10 sections |
| Thermacare Heat Therapy Max Strength Lidocaine Pain Relief Gel | HUMAN OTC DRUG LABEL | 2 | 69693-003 | GEL | 10 g | TOPICAL | OTC Monograph Drug | 10 sections |
| Thermacare Max Strength Lidocaine | HUMAN OTC DRUG LABEL | 2 | 69693-004 | SPRAY | 10 g | TOPICAL | OTC Monograph Drug | 10 sections |
| CVS Maximum Strength LIDOCAINE PLUS | HUMAN OTC DRUG LABEL | 2 | 69842-573 | SPRAY | 10 g | TOPICAL | OTC Monograph Drug | 15 sections |
| HealthWise Lidocaine Plus Cream | HUMAN OTC DRUG LABEL | 2 | 71101-037 | CREAM | 10 g | TOPICAL | OTC Monograph Drug | 13 sections |
| Protocoxil | HUMAN OTC DRUG LABEL | 1 | 71416-001 | GEL | 100 mg | TOPICAL | OTC monograph not final | 12 sections |
| Hand Sanitizer | HUMAN OTC DRUG LABEL | 3 | 73166-602 | GEL | 0.30 g | TOPICAL | unapproved drug other | 5 sections |
| Carpal Comfort | HUMAN OTC DRUG LABEL | 2 | 73214-001 | CREAM | 10 mg | TOPICAL | OTC monograph not final | 12 sections |
| Meijer Pain Lidocaine Plus RelievingAnalgesic | HUMAN OTC DRUG LABEL | 2 | 79481-0084 | LIQUID | 100 mg | TOPICAL | OTC Monograph Drug | 15 sections |