flusalan 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
brominated salicylamide derivatives disinfectant	3236	4776-06-1

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

fluorosalan
fluorophene
fluorsalan
flusalan

Molecular weight: 439.03
Formula: C14H8Br2F3NO2
CLOGP: 6.22
LIPINSKI: 1
HAC: 3
HDO: 2
TPSA: 49.33
ALOGS: -5.20
ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	4.66	acidic
pKa2	9.3	acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Kappa-type opioid receptor	GPCR	P41145	OPRK_HUMAN		IC50	6.80		CHEMBL
Mu-type opioid receptor	GPCR		OPRM_MOUSE		IC50	8.07		CHEMBL
Mu-type opioid receptor	GPCR		OPRM_CAVPO		IC50	7.92		CHEMBL

External reference:

ID	Source
D04222	KEGG_DRUG
CHEBI:135715	CHEBI
CHEMBL283552	ChEMBL_ID
C013535	MESH_SUPPLEMENTAL_RECORD_UI
20906	PUBCHEM_CID
C2826091	UMLSCUI
2141	INN_ID
80OFG3WPYD	UNII

Pharmaceutical products:

None