bietamiverine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
spasmolytics with a papaverine-like action	3025	479-81-2

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

bietamiverine monohydrochloride
bietamiverine hydrochloride
bietamiverine
dietamiverine
novosaprol
paparid
spasmaparid

Molecular weight: 318.46
Formula: C19H30N2O2
CLOGP: 4.41
LIPINSKI: 0
HAC: 4
HDO: 0
TPSA: 32.78
ALOGS: -3
ROTB: 9

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	9.19	Basic
pKa2	6.92	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Muscarinic acetylcholine receptor M1	GPCR	P11229	ACM1_HUMAN		Ki	6.57		CHEMBL
Muscarinic acetylcholine receptor M2	GPCR	P08172	ACM2_HUMAN		Ki	5.99		CHEMBL
Muscarinic acetylcholine receptor M3	GPCR	P20309	ACM3_HUMAN		Ki	6.73		CHEMBL

External reference:

ID	Source
1477-10-7	SECONDARY_CAS_RN
C0602297	UMLSCUI
CHEBI:135362	CHEBI
CHEMBL2110892	ChEMBL_ID
CHEMBL2106541	ChEMBL_ID
C005680	MESH_SUPPLEMENTAL_RECORD_UI
72064	PUBCHEM_CID
669	INN_ID
4MGI916O6Y	UNII

Pharmaceutical products:

None