Stem definition | Drug id | CAS RN |
---|---|---|
2737 | 60-49-1 |
Dose | Unit | Route |
---|---|---|
0.13 | g | O |
None
Date | Agency | Company | Orphan |
---|---|---|---|
Sept. 15, 1954 | FDA |
None
None
None
None
Source | Code | Description |
---|---|---|
ATC | A03AB08 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS Synthetic anticholinergics, quaternary ammonium compounds |
CHEBI has role | CHEBI:48876 | muscarinic antagonists |
CHEBI has role | CHEBI:49201 | anti-ulcer drugs |
CHEBI has role | CHEBI:53784 | antispasmodics |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Peptic ulcer | indication | 13200003 | DOID:750 |
Gastric ulcer | indication | 397825006 | DOID:10808 |
Irritable bowel syndrome | off-label use | 10743008 | DOID:9778 |
Suicidal thoughts | contraindication | 6471006 | |
Alcoholism | contraindication | 7200002 | |
Lowered convulsive threshold | contraindication | 19260006 | |
Substance abuse | contraindication | 66214007 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Seizure disorder | contraindication | 128613002 | |
Acute intermittent porphyria | contraindication | 234422006 | DOID:3890 |
Disease of liver | contraindication | 235856003 | DOID:409 |
Pregnancy, function | contraindication | 289908002 | |
Breastfeeding (mother) | contraindication | 413712001 |
None
None
None
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M1 | GPCR | ANTAGONIST | CHEMBL | CHEMBL | |||||
Muscarinic acetylcholine receptor M3 | GPCR | ANTAGONIST | CHEMBL | CHEMBL |
ID | Source |
---|---|
4019955 | VUID |
N0000148040 | NUI |
D00723 | KEGG_DRUG |
4310-35-4 | SECONDARY_CAS_RN |
4017914 | VANDF |
4019955 | VANDF |
C0077081 | UMLSCUI |
CHEBI:9701 | CHEBI |
CHEMBL1201354 | ChEMBL_ID |
DB00505 | DRUGBANK_ID |
C005386 | MESH_SUPPLEMENTAL_RECORD_UI |
20299 | PUBCHEM_CID |
125-99-5 | SECONDARY_CAS_RN |
7HE50A367X | UNII |
38617 | RXNORM |
001744 | NDDF |
004700 | NDDF |
36872003 | SNOMEDCT_US |
76787008 | SNOMEDCT_US |
CHEMBL1200771 | ChEMBL_ID |
CHEMBL2107686 | ChEMBL_ID |
551 | INN_ID |
None