tribenoside 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
2730 10310-32-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • tribenosid
  • tribenoside
  • glyvenal
  • glyvenol
  • tribenzoside
anti-inflammatory agent used in edema of extremities, varicose veins & phlebitis; minor descriptor (75-86); on-line & INDEX MEDICUS search GLYCOSIDES (75-86); RN given refers to parent cpd without isomeric designation
  • Molecular weight: 478.59
  • Formula: C29H34O6
  • CLOGP: 4.62
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 1
  • TPSA: 66.38
  • ALOGS: -5.17
  • ROTB: 13

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,BRAF,BTK,CAMK2D,CDK5,CDK9,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,MAPK7,NTRK2,PDK1,PDK2,PDK4,PRKDC,TEK,TGFBR1 20
kinase-selectivity-class AXL,GRK2 2
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C05AX05 CARDIOVASCULAR SYSTEM
VASOPROTECTIVES
AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
Other agents for treatment of hemorrhoids and anal fissures for topical use
ATC C05CX01 CARDIOVASCULAR SYSTEM
VASOPROTECTIVES
CAPILLARY STABILIZING AGENTS
Other capillary stabilizing agents
MeSH PA D000700 Analgesics
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018501 Antirheumatic Agents
MeSH PA D018689 Sensory System Agents
MeSH PA D018712 Analgesics, Non-Narcotic
CHEBI has role CHEBI:35554 cardiovascular drug

Related Drugs by ATC class:

C05AX Other agents for treatment of hemorrhoids and anal fissures for topical use 1 drug
phenylephrine
C05CX Other capillary stabilizing agents 1 drug
naftazone

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.28 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01095 KEGG_DRUG
C0077015 UMLSCUI
CHEBI:32256 CHEBI
CHEMBL3301681 ChEMBL_ID
DB13227 DRUGBANK_ID
C100302 MESH_SUPPLEMENTAL_RECORD_UI
2463 INN_ID
Z7N0Y673NU UNII
196122 PUBCHEM_CID
38557 RXNORM
005724 NDDF

Pharmaceutical products:

None