tofenacin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
muscarinic receptors antagonists 2692 15301-93-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • elamol
  • tofenacin monohydrochloride
  • tofenacin hydrochloride
  • tofenacin
  • demethylorphenadrine
  • tofenacine
  • tofenacin HCl
  • Molecular weight: 255.36
  • Formula: C17H21NO
  • CLOGP: 3.31
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 1
  • TPSA: 21.26
  • ALOGS: -4.75
  • ROTB: 6

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None UK Medicines and Healthcare Products Regulatory Agency (MHRA)

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D018678 Cholinergic Agents
MeSH PA D018680 Cholinergic Antagonists
MeSH PA D018377 Neurotransmitter Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Depressive disorder indication 35489007
Glaucoma contraindication 23986001 DOID:1686




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.51 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D06175 KEGG_DRUG
10488-36-5 SECONDARY_CAS_RN
C0076783 UMLSCUI
CHEBI:135046 CHEBI
CHEMBL2110923 ChEMBL_ID
CHEMBL2106673 ChEMBL_ID
C005834 MESH_SUPPLEMENTAL_RECORD_UI
25315 PUBCHEM_CID
1753 INN_ID
C4A112M10H UNII

Pharmaceutical products:

None