DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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L1000
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Substructure SMILES Example:
n1cnccc1
tisopurine 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
2682
5334-23-6
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
tisopurine
thiopurinol
4-thio analog of allopurinol; structure
Molecular weight: 152.18
Formula: C5H4N4S
CLOGP: -1.09
LIPINSKI: 0
HAC: 4
HDO: 2
TPSA: 53.07
ALOGS: -2.35
ROTB: 0
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
M04AA02
MUSCULO-SKELETAL SYSTEM
ANTIGOUT PREPARATIONS
ANTIGOUT PREPARATIONS
Preparations inhibiting uric acid production
MeSH PA
D018501
Antirheumatic Agents
MeSH PA
D006074
Gout Suppressants
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
7.16
acidic
pKa2
11.11
acidic
pKa3
3.52
Basic
pKa4
2.84
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
005362
NDDF
135445058
PUBCHEM_CID
38136
RXNORM
3842
INN_ID
79F9I2R16M
UNII
C005832
MESH_SUPPLEMENTAL_RECORD_UI
C0076516
UMLSCUI
CHEBI:134776
CHEBI
CHEMBL119423
ChEMBL_ID
D07278
KEGG_DRUG
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Pharmaceutical products:
None
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tisopurine