tisopurine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2682 5334-23-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • tisopurine
  • thiopurinol
4-thio analog of allopurinol; structure
  • Molecular weight: 152.18
  • Formula: C5H4N4S
  • CLOGP: -1.09
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 2
  • TPSA: 53.07
  • ALOGS: -2.35
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M04AA02 MUSCULO-SKELETAL SYSTEM
ANTIGOUT PREPARATIONS
ANTIGOUT PREPARATIONS
Preparations inhibiting uric acid production
MeSH PA D018501 Antirheumatic Agents
MeSH PA D006074 Gout Suppressants

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.16 acidic
pKa2 11.11 acidic
pKa3 3.52 Basic
pKa4 2.84 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07278 KEGG_DRUG
C0076516 UMLSCUI
CHEBI:134776 CHEBI
CHEMBL119423 ChEMBL_ID
DB13807 DRUGBANK_ID
135445058 PUBCHEM_CID
3842 INN_ID
C005832 MESH_SUPPLEMENTAL_RECORD_UI
79F9I2R16M UNII
38136 RXNORM
005362 NDDF

Pharmaceutical products:

None