thymopentin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2645 | 69558-55-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Synthetic pentapeptide corresponding to the amino acids 32-36 of thymopoietin and exhibiting the full biological activity of the natural hormone. It is an immunomodulator which has been studied for possible use in the treatment of rheumatoid arthritis, AIDS, and other primary immunodeficiencies.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Bone marrow failure | 33.12 | 31.22 | 5 | 3 | 29285 | 63459729 |
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | L03AX09 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS IMMUNOSTIMULANTS IMMUNOSTIMULANTS Other immunostimulants |
| MeSH PA | D000276 | Adjuvants, Immunologic |
| MeSH PA | D007155 | Immunologic Factors |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.26 | acidic |
| pKa2 | 3.94 | acidic |
| pKa3 | 10.6 | acidic |
| pKa4 | 12.76 | acidic |
| pKa5 | 13.37 | acidic |
| pKa6 | 10.81 | Basic |
| pKa7 | 10.0 | Basic |
| pKa8 | 7.43 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| N0000167482 | NUI |
| D06117 | KEGG_DRUG |
| C0080225 | UMLSCUI |
| CHEBI:135870 | CHEBI |
| CHEMBL156025 | ChEMBL_ID |
| D016305 | MESH_DESCRIPTOR_UI |
| DB11996 | DRUGBANK_ID |
| 5146 | INN_ID |
| O3Y80ZF13F | UNII |
| 451417 | PUBCHEM_CID |
| 40230 | RXNORM |
| 006776 | NDDF |
Pharmaceutical products:
None