thiamphenicol glycinate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, produced by Streptomyces strains 2625 2393-92-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • thiamphenicol glycinate
  • thiamphenicol glycine ester
  • thiophenicol glycinate
  • urfamicin
  • thiamphenicol aminoacetate hydrochloride
  • thiamphenicol aminoacetate HCl
  • Molecular weight: 413.27
  • Formula: C14H18Cl2N2O6S
  • CLOGP: -0.98
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 3
  • TPSA: 135.79
  • ALOGS: -3.07
  • ROTB: 9

Drug dosage:

None

ADMET properties:

PropertyValueReference
Vd (Volume of distribution) 0.13 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 9.60 mL/min/kg Lombardo F, Berellini G, Obach RS
fu (Fraction unbound in plasma) 0.27 % Lombardo F, Berellini G, Obach RS
t_half (Half-life) 0.28 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
CHEBI has role CHEBI:33281 antibiotics
CHEBI has role CHEBI:35705 immunosuppressive agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.2 acidic
pKa2 7.75 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D08583 KEGG_DRUG
2611-61-2 SECONDARY_CAS_RN
C0612489 UMLSCUI
CHEBI:135669 CHEBI
CHEBI:32215 CHEBI
TH8 PDB_CHEM_ID
CHEMBL1697822 ChEMBL_ID
C028813 MESH_SUPPLEMENTAL_RECORD_UI
115817 PUBCHEM_CID
10463 RXNORM
005347 NDDF
005348 NDDF
363552000 SNOMEDCT_US
713763007 SNOMEDCT_US
734975009 SNOMEDCT_US
C0039854 UMLSCUI
CHEMBL1236282 ChEMBL_ID
DB08621 DRUGBANK_ID
935 INN_ID
D013839 MESH_DESCRIPTOR_UI
27200 PUBCHEM_CID
88VGC22BWE UNII

Pharmaceutical products:

None