DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
thiamphenicol glycinate 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
antibiotics, produced by Streptomyces strains
2625
2393-92-2
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
thiamphenicol glycinate
thiamphenicol glycine ester
thiophenicol glycinate
urfamicin
thiamphenicol aminoacetate hydrochloride
thiamphenicol aminoacetate HCl
Molecular weight: 413.27
Formula: C14H18Cl2N2O6S
CLOGP: -0.98
LIPINSKI: 0
HAC: 8
HDO: 3
TPSA: 135.79
ALOGS: -3.07
ROTB: 9
Drug dosage:
None
ADMET properties:
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Property
Value
Reference
CL (Clearance)
9.60 mL/min/kg
Lombardo F, Berellini G, Obach RS
t_half (Half-life)
0.28 hours
Lombardo F, Berellini G, Obach RS
fu (Fraction unbound in plasma)
0.27 %
Lombardo F, Berellini G, Obach RS
Vd (Volume of distribution)
0.13 L/kg
Lombardo F, Berellini G, Obach RS
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Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
CHEBI has role
CHEBI:33281
antibiotics
CHEBI has role
CHEBI:35705
immunosuppressive agents
MeSH PA
D000900
Anti-Bacterial Agents
MeSH PA
D000890
Anti-Infective Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
10.2
acidic
pKa2
7.75
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
TH8
PDB_CHEM_ID
005347
NDDF
005348
NDDF
10463
RXNORM
115817
PUBCHEM_CID
2611-61-2
SECONDARY_CAS_RN
27200
PUBCHEM_CID
363552000
SNOMEDCT_US
713763007
SNOMEDCT_US
734975009
SNOMEDCT_US
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Pharmaceutical products:
None
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thiamphenicol glycinate