tebipenem pivoxil Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
analogues of penicillanic acid antibiotics modified in the five-membered ring 2574 161715-24-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • tebipenem pivoxil
  • orapenem
an oral carbapenem antibiotic, against penicillin-nonsusceptible Streptococcus pneumoniae
  • Molecular weight: 497.63
  • Formula: C22H31N3O6S2
  • CLOGP: 1.98
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 1
  • TPSA: 108.74
  • ALOGS: -3.47
  • ROTB: 9

Drug dosage:

DoseUnitRoute
0.56 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01DH06 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
OTHER BETA-LACTAM ANTIBACTERIALS
Carbapenems

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.8 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D09598 KEGG_DRUG
161715-21-5 SECONDARY_CAS_RN
C2699902 UMLSCUI
C1568612 UMLSCUI
CHEBI:135799 CHEBI
1TE PDB_CHEM_ID
CHEMBL2107486 ChEMBL_ID
CHEMBL576981 ChEMBL_ID
C500135 MESH_SUPPLEMENTAL_RECORD_UI
7924 INN_ID
95AK1A52I8 UNII
Q2TWQ1I31U UNII
9892071 PUBCHEM_CID
9800194 PUBCHEM_CID
10864 IUPHAR_LIGAND_ID

Pharmaceutical products:

None