tebipenem pivoxil 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
analogues of penicillanic acid antibiotics modified in the five-membered ring 2574 161715-24-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • tebipenem pivoxil
  • orapenem
an oral carbapenem antibiotic, against penicillin-nonsusceptible Streptococcus pneumoniae
  • Molecular weight: 497.63
  • Formula: C22H31N3O6S2
  • CLOGP: 2.77
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 1
  • TPSA: 108.74
  • ALOGS: -3.47
  • ROTB: 9

Drug dosage:

DoseUnitRoute
0.56 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01DH06 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
OTHER BETA-LACTAM ANTIBACTERIALS
Carbapenems

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.8 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D09598 KEGG_DRUG
C2699902 UMLSCUI
CHEBI:135799 CHEBI
1TE PDB_CHEM_ID
CHEMBL2107486 ChEMBL_ID
C120999 MESH_SUPPLEMENTAL_RECORD_UI
10864 IUPHAR_LIGAND_ID
C500135 MESH_SUPPLEMENTAL_RECORD_UI
7924 INN_ID
161715-21-5 SECONDARY_CAS_RN
95AK1A52I8 UNII
9892071 PUBCHEM_CID
9800194 PUBCHEM_CID
C1568612 UMLSCUI
CHEMBL576981 ChEMBL_ID
Q2TWQ1I31U UNII

Pharmaceutical products:

None