sulfobromophthalein 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2531 | 71-67-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A phenolphthalein that is used as a diagnostic aid in hepatic function determination.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | V04CE02 | VARIOUS DIAGNOSTIC AGENTS OTHER DIAGNOSTIC AGENTS Tests for liver functional capacity |
| MeSH PA | D004396 | Coloring Agents |
| MeSH PA | D007202 | Indicators and Reagents |
| CHEBI has role | CHEBI:37958 | dyes |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Diagnostic aid | indication | 2949005 | |
| Acute nephropathy | contraindication | 58574008 | |
| Hepatic failure | contraindication | 59927004 | |
| Kidney disease | contraindication | 90708001 | DOID:557 |
| Hb SS disease | contraindication | 127040003 | DOID:10923 |
| Asthma | contraindication | 195967001 | DOID:2841 |
| Pregnancy, function | contraindication | 289908002 | |
| Pheochromocytoma | contraindication | 302835009 | |
| Hypertensive Emergencies | contraindication |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.1 | acidic |
| pKa2 | 8.7 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Hematopoietic prostaglandin D synthase | Enzyme | IC50 | 4.57 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| N0000166608 | NUI |
| C0038753 | UMLSCUI |
| CHEBI:63827 | CHEBI |
| BSP | PDB_CHEM_ID |
| CHEMBL574431 | ChEMBL_ID |
| CHEMBL453904 | ChEMBL_ID |
| D013448 | MESH_DESCRIPTOR_UI |
| DB13215 | DRUGBANK_ID |
| 0C2P5QKL36 | UNII |
| 5345 | PUBCHEM_CID |
| 10212 | RXNORM |
| 004877 | NDDF |
| 297-83-6 | SECONDARY_CAS_RN |
Pharmaceutical products:
None