sulfobromophthalein 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2531 71-67-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • sulfobromophthalein
  • sulphobromophthalein sodium
  • bromosulfophthalein
  • bromosulphalein
  • sodium sulfobromophthalein
  • phenoltetrabromophthaleinsulfonate
  • bromsulfophthalein
  • tetrabromsulfthalein
A phenolphthalein that is used as a diagnostic aid in hepatic function determination.
  • Molecular weight: 794.03
  • Formula: C20H10Br4O10S2
  • CLOGP: -0.14
  • LIPINSKI: 1
  • HAC: 10
  • HDO: 4
  • TPSA: 175.50
  • ALOGS: -5
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V04CE02 VARIOUS
DIAGNOSTIC AGENTS
OTHER DIAGNOSTIC AGENTS
Tests for liver functional capacity
MeSH PA D004396 Coloring Agents
MeSH PA D007202 Indicators and Reagents
CHEBI has role CHEBI:37958 dyes

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Diagnostic aid indication 2949005
Acute nephropathy contraindication 58574008
Hepatic failure contraindication 59927004
Kidney disease contraindication 90708001 DOID:557
Hb SS disease contraindication 127040003 DOID:10923
Asthma contraindication 195967001 DOID:2841
Pregnancy, function contraindication 289908002
Pheochromocytoma contraindication 302835009
Hypertensive Emergencies contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.1 acidic
pKa2 8.7 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Hematopoietic prostaglandin D synthase Enzyme IC50 4.57 CHEMBL

External reference:

IDSource
N0000166608 NUI
C0038753 UMLSCUI
CHEBI:63827 CHEBI
BSP PDB_CHEM_ID
CHEMBL574431 ChEMBL_ID
CHEMBL453904 ChEMBL_ID
D013448 MESH_DESCRIPTOR_UI
DB13215 DRUGBANK_ID
0C2P5QKL36 UNII
5345 PUBCHEM_CID
10212 RXNORM
004877 NDDF
297-83-6 SECONDARY_CAS_RN

Pharmaceutical products:

None