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galactose 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 1271 | 59-23-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood.
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,AURKA,AXL,BRAF,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,ERBB2,FLT3,GRK2,ITK,MAP2K6,MAP3K21,MAPK10,MAPK7,NTRK2,PDK2,PDK4,PIK3CB,PIK3CD,PRKCD,PRKDC,SIK2,STK33,TEK | 29 | |||
| kinase-selectivity-class | ACVRL1,AXL,BMX,CDK1,CDK16,CDK2,CDK3,CDK4,CDK6,CDK7,CDK9,CHUK,DYRK1A,INSR,IRAK3,IRAK4,MAP2K6,MAP3K14,PDK1,PIK3CD,TGFBR1,ZAP70 | 22 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | V04CE01 | VARIOUS DIAGNOSTIC AGENTS OTHER DIAGNOSTIC AGENTS Tests for liver functional capacity |
| ATC | V08DA02 | VARIOUS CONTRAST MEDIA ULTRASOUND CONTRAST MEDIA Ultrasound contrast media |
| CHEBI has role | CHEBI:78675 | fundamental metabolite |
Related Drugs by ATC class:
V04CE Tests for liver functional capacity 1 drug
V08DA Ultrasound contrast media 4 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 11.87 | acidic |
| pKa2 | 13.08 | acidic |
| pKa3 | 13.91 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Jacalin | Secreted | Kd | 4.80 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| 4018618 | VUID |
| N0000146931 | NUI |
| D04291 | KEGG_DRUG |
| 4018618 | VANDF |
| C0016945 | UMLSCUI |
| CHEBI:28260 | CHEBI |
| GAL | PDB_CHEM_ID |
| CHEMBL6067641 | ChEMBL_ID |
| DB11735 | DRUGBANK_ID |
| D005690 | MESH_DESCRIPTOR_UI |
| 6036 | PUBCHEM_CID |
| X2RN3Q8DNE | UNII |
| 4626 | RXNORM |
| 006112 | NDDF |
| 38182007 | SNOMEDCT_US |
| 423410006 | SNOMEDCT_US |
Pharmaceutical products:
None