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sulbutiamine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2494 | 3286-46-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
a glutamatergic, dopaminergic, and neurotropic agent which in animals improved learning ability & resistance to fatigue
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2B,AXL,BRAF,BTK,CAMK2D,CDK5,CDK9,DYRK1B,EIF2AK3,ERBB2,GRK2,ITK,MAPK7,NTRK2,PDK1,PDK2,PIK3CB,PRKDC,STK33,TEK,TTK | 21 | |||
| kinase-selectivity-class | GRK2 | 1 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A11DA02 | ALIMENTARY TRACT AND METABOLISM VITAMINS VITAMIN B1, PLAIN AND IN COMBINATION WITH VITAMIN B6 AND B12 Vitamin B1, plain |
Related Drugs by ATC class:
A11DA Vitamin B1, plain 2 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 7.67 | Basic |
| pKa2 | 7.07 | Basic |
| pKa3 | 1.26 | Basic |
| pKa4 | 0.66 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4032901 | VUID |
| N0000189534 | NUI |
| D01319 | KEGG_DRUG |
| 4032901 | VANDF |
| C0075501 | UMLSCUI |
| CHEBI:31290 | CHEBI |
| CHEMBL1874002 | ChEMBL_ID |
| DB13416 | DRUGBANK_ID |
| C031331 | MESH_SUPPLEMENTAL_RECORD_UI |
| 4827 | INN_ID |
| 42NCM1BW43 | UNII |
| 3002120 | PUBCHEM_CID |
| 37317 | RXNORM |
| 005898 | NDDF |
| 699182008 | SNOMEDCT_US |
| 714625004 | SNOMEDCT_US |
Pharmaceutical products:
None