ripazepam 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
diazepam derivatives 2386 26308-28-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • CI-683
  • CI 683
  • ripazepam
  • pyrazapon
  • Molecular weight: 268.32
  • Formula: C15H16N4O
  • CLOGP: 1.34
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 59.28
  • ALOGS: -3.02
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.91 acidic
pKa2 4.68 Basic
pKa3 1.22 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
GABA-A receptor; anion channel Ion channel IC50 6.17 CHEMBL

External reference:

IDSource
D05733 KEGG_DRUG
C0073389 UMLSCUI
CHEBI:82529 CHEBI
CHEMBL159298 ChEMBL_ID
C009116 MESH_SUPPLEMENTAL_RECORD_UI
33474 PUBCHEM_CID
3751 INN_ID
92000WH9C9 UNII

Pharmaceutical products:

None