aranidipine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
calcium channel blockers, nifedipine derivatives 234 86780-90-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • aranidipine
  • sapresta
  • Molecular weight: 388.38
  • Formula: C19H20N2O7
  • CLOGP: 2.56
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 1
  • TPSA: 124.84
  • ALOGS: -4.54
  • ROTB: 8

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypertensive disorder indication 38341003 DOID:10763




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.5 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Voltage-gated L-type calcium channel Ion channel BLOCKER DRUG LABEL KEGG DRUG

External reference:

IDSource
D01562 KEGG_DRUG
C0165312 UMLSCUI
CHEBI:31232 CHEBI
CHEMBL2104030 ChEMBL_ID
DB09229 DRUGBANK_ID
C059427 MESH_SUPPLEMENTAL_RECORD_UI
2225 PUBCHEM_CID
11744 IUPHAR_LIGAND_ID
7071 INN_ID
4Y7UR6X2PO UNII

Pharmaceutical products:

None