aprobarbital 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
hypnotics, barbituric acid derivatives 232 77-02-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • aprobarbital
  • allonal
  • allylisopropylbarbituric acid
  • allylisopropylmalonylurea
  • allylpropymal
  • allypropymal
  • aprobarbitone
  • isopropylallylbarbituric acid
  • Molecular weight: 210.23
  • Formula: C10H14N2O3
  • CLOGP: 1.10
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 75.27
  • ALOGS: -1.61
  • ROTB: 3

Drug dosage:

DoseUnitRoute
0.10 g O
0.10 g P

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N05CA05 NERVOUS SYSTEM
PSYCHOLEPTICS
HYPNOTICS AND SEDATIVES
Barbiturates, plain

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
General anesthesia indication 50697003
Severe anxiety (panic) indication 80583007
Insomnia indication 193462001




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.05 acidic
pKa2 9.75 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4017804 VUID
N0000179035 NUI
17381 RXNORM
C0051241 UMLSCUI
CHEBI:2791 CHEBI
CHEMBL7863 ChEMBL_ID
DB01352 DRUGBANK_ID
6464 PUBCHEM_CID
C006470 MESH_SUPPLEMENTAL_RECORD_UI
1161 INN_ID
Q0YKG9L6RF UNII
398724001 SNOMEDCT_US
80532007 SNOMEDCT_US
4017804 VANDF
001418 NDDF

Pharmaceutical products:

None