propacetamol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2290 | 66532-85-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
prodrug for acetaminophen
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 6 | g | P |
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Febrile neutropenia | 43.56 | 41.77 | 14 | 118 | 118435 | 63370455 |
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Neutropenia | 49.90 | 41.99 | 25 | 352 | 287685 | 79456326 |
| Febrile neutropenia | 45.75 | 41.99 | 22 | 355 | 230977 | 79513034 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | N02BE05 | NERVOUS SYSTEM ANALGESICS OTHER ANALGESICS AND ANTIPYRETICS Anilides |
| MeSH PA | D000700 | Analgesics |
| MeSH PA | D018712 | Analgesics, Non-Narcotic |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D000894 | Anti-Inflammatory Agents, Non-Steroidal |
| MeSH PA | D018501 | Antirheumatic Agents |
| MeSH PA | D002491 | Central Nervous System Agents |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D018689 | Sensory System Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 7.85 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D07294 | KEGG_DRUG |
| C0084186 | UMLSCUI |
| CHEBI:135089 | CHEBI |
| CHEMBL1851805 | ChEMBL_ID |
| DB09288 | DRUGBANK_ID |
| C063776 | MESH_SUPPLEMENTAL_RECORD_UI |
| 68865 | PUBCHEM_CID |
| 5400 | INN_ID |
| 5CHW4JMR82 | UNII |
| 005336 | NDDF |
| 1285524005 | SNOMEDCT_US |
Pharmaceutical products:
None