propacetamol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2290 66532-85-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • propacetamol
  • proparacetamol
prodrug for acetaminophen
  • Molecular weight: 264.33
  • Formula: C14H20N2O3
  • CLOGP: 1.82
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 58.64
  • ALOGS: -2.71
  • ROTB: 7

Drug dosage:

DoseUnitRoute
6 g P

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Neutropenia 50.07 46.42 25 339 239599 64258769

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N02BE05 NERVOUS SYSTEM
ANALGESICS
OTHER ANALGESICS AND ANTIPYRETICS
Anilides
MeSH PA D000700 Analgesics
MeSH PA D018712 Analgesics, Non-Narcotic
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D018501 Antirheumatic Agents
MeSH PA D002491 Central Nervous System Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.85 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07294 KEGG_DRUG
C0084186 UMLSCUI
CHEBI:135089 CHEBI
CHEMBL1851805 ChEMBL_ID
DB09288 DRUGBANK_ID
C063776 MESH_SUPPLEMENTAL_RECORD_UI
68865 PUBCHEM_CID
5400 INN_ID
5CHW4JMR82 UNII
005336 NDDF

Pharmaceutical products:

None