pipotiazine palmitate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	2193	37517-26-3

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

piportil
pipotiazine palmitate
piportil depot

Molecular weight: 714.08
Formula: C40H63N3O4S2
CLOGP: 11.70
LIPINSKI: 2
HAC: 7
HDO: 0
TPSA: 70.16
ALOGS: -7.43
ROTB: 23

Drug dosage:

Dose	Unit	Route
10	mg	O
5	mg	P

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	N05AC04	NERVOUS SYSTEM PSYCHOLEPTICS ANTIPSYCHOTICS Phenothiazines with piperidine structure

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Schizophrenia	indication	58214004	DOID:5419

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	9.12	Basic
pKa2	3.06	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
D(2) dopamine receptor	GPCR	P14416	DRD2_HUMAN	ANTAGONIST	Ki	9.70		PDSP	IUPHAR
D(3) dopamine receptor	GPCR	P35462	DRD3_HUMAN		Ki	9.55		PDSP

External reference:

ID	Source
D02680	KEGG_DRUG
CHEBI:135769	CHEBI
CHEMBL2106439	ChEMBL_ID
DB01621	DRUGBANK_ID
235745	RXNORM
003492	NDDF
003493	NDDF
349879008	SNOMEDCT_US
395832003	SNOMEDCT_US
395995004	SNOMEDCT_US
C0770895	UMLSCUI
C0031968	UMLSCUI
37767	PUBCHEM_CID
3046	INN_ID
39860-99-6	SECONDARY_CAS_RN
62867	PUBCHEM_CID
7557	IUPHAR_LIGAND_ID
4Q3H01QRMI	UNII
L903J9JPYV	UNII

Pharmaceutical products:

None