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2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
pipotiazine palmitate 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
2193
37517-26-3
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
piportil
pipotiazine palmitate
piportil depot
Molecular weight: 714.08
Formula: C40H63N3O4S2
CLOGP: 11.70
LIPINSKI: 2
HAC: 7
HDO: 0
TPSA: 70.16
ALOGS: -7.43
ROTB: 23
Drug dosage:
Dose
Unit
Route
10
mg
O
5
mg
P
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
N05AC04
NERVOUS SYSTEM
PSYCHOLEPTICS
ANTIPSYCHOTICS
Phenothiazines with piperidine structure
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Schizophrenia
indication
58214004
DOID:5419
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
9.12
Basic
pKa2
3.06
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
D(2) dopamine receptor
GPCR
P14416
DRD2_HUMAN
ANTAGONIST
Ki
9.70
PDSP
IUPHAR
D(3) dopamine receptor
GPCR
P35462
DRD3_HUMAN
Ki
9.55
PDSP
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External reference:
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entries
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ID
Source
003492
NDDF
003493
NDDF
235745
RXNORM
3046
INN_ID
349879008
SNOMEDCT_US
37767
PUBCHEM_CID
395832003
SNOMEDCT_US
395995004
SNOMEDCT_US
39860-99-6
SECONDARY_CAS_RN
4Q3H01QRMI
UNII
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Pharmaceutical products:
None
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pipotiazine palmitate