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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
pipamazine 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
2180
84-04-8
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
pipamazine
mornidine
nausidol
nometine
Molecular weight: 401.95
Formula: C21H24ClN3OS
CLOGP: 4.12
LIPINSKI: 0
HAC: 4
HDO: 1
TPSA: 49.57
ALOGS: -5.23
ROTB: 5
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
13.41
acidic
pKa2
8.95
Basic
pKa3
2.21
Basic
Showing 1 to 3 of 3 entries
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
D(1A) dopamine receptor
GPCR
P21728
DRD1_HUMAN
Ki
7.80
DRUG MATRIX
D(2) dopamine receptor
GPCR
P14416
DRD2_HUMAN
Ki
8.87
DRUG MATRIX
Alpha-2A adrenergic receptor
GPCR
P08913
ADA2A_HUMAN
Ki
7.60
DRUG MATRIX
Sigma non-opioid intracellular receptor 1
Membrane receptor
Q99720
SGMR1_HUMAN
Ki
7.32
DRUG MATRIX
Sodium-dependent serotonin transporter
Transporter
P31645
SC6A4_HUMAN
Ki
6.46
DRUG MATRIX
Sodium-dependent noradrenaline transporter
Transporter
P23975
SC6A2_HUMAN
Ki
6.35
DRUG MATRIX
5-hydroxytryptamine receptor 1A
GPCR
P08908
5HT1A_HUMAN
Ki
5.99
DRUG MATRIX
5-hydroxytryptamine receptor 2A
GPCR
P28223
5HT2A_HUMAN
Ki
9.26
DRUG MATRIX
5-hydroxytryptamine receptor 2B
GPCR
P41595
5HT2B_HUMAN
Ki
7.51
DRUG MATRIX
5-hydroxytryptamine receptor 2C
GPCR
P28335
5HT2C_HUMAN
Ki
7.96
DRUG MATRIX
Showing 1 to 10 of 23 entries
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External reference:
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ID
Source
653552FH1N
UNII
6761
PUBCHEM_CID
884
INN_ID
89775008
SNOMEDCT_US
C0301468
UMLSCUI
CHEBI:135641
CHEBI
CHEMBL1909072
ChEMBL_ID
D02606
KEGG_DRUG
Showing 1 to 8 of 8 entries
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Pharmaceutical products:
None
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pipamazine