piketoprofen 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
anti-inflammatory agents, ibuprofen derivatives	2165	60576-13-8

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

calmatel
piketoprofen

Molecular weight: 344.41
Formula: C22H20N2O2
CLOGP: 3.88
LIPINSKI: 0
HAC: 4
HDO: 1
TPSA: 59.06
ALOGS: -5.16
ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	M02AA28	MUSCULO-SKELETAL SYSTEM TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN Antiinflammatory preparations, non-steroids for topical use

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Pain	indication	22253000

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	11.9	acidic
pKa2	4.17	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Prostaglandin G/H synthase 1	Enzyme	P23219	PGH1_HUMAN	INHIBITOR				KEGG DRUG	KEGG DRUG
Prostaglandin G/H synthase 2	Enzyme	P35354	PGH2_HUMAN	INHIBITOR				KEGG DRUG	KEGG DRUG

External reference:

ID	Source
D08374	KEGG_DRUG
C0285260	UMLSCUI
CHEBI:135455	CHEBI
CHEMBL2106966	ChEMBL_ID
C048832	MESH_SUPPLEMENTAL_RECORD_UI
68801	PUBCHEM_CID
4556	INN_ID
362QBC4NL0	UNII
82910	RXNORM
009027	NDDF
136501000146105	SNOMEDCT_US

Pharmaceutical products:

None