oxagrelate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
platelet aggregation inhibitors 2156 56611-65-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oxagrelate
  • phthalazinol
  • EG 626
  • Molecular weight: 276.29
  • Formula: C14H16N2O4
  • CLOGP: 0.61
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 2
  • TPSA: 87.99
  • ALOGS: -3.24
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D010726 Phosphodiesterase Inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.9 acidic
pKa2 13.44 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Phosphodiesterase 3 Enzyme Ki 5.85 CHEMBL
Phosphodiesterase 1 Enzyme Ki 5 CHEMBL

External reference:

IDSource
V17MYO89WO UNII
D05278 KEGG_DRUG
C2825274 UMLSCUI
CHEBI:135142 CHEBI
CHEMBL153427 ChEMBL_ID
41946 PUBCHEM_CID
5187 INN_ID
C011329 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None