ozagrel Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
platelet aggregation inhibitors 2043 82571-53-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ozagrel sodium
  • ozagrel
  • sodium ozagrel
  • xanbon
  • ozagrel hydrochloride
  • ozagrel hydrochloride hydrate
  • domenan
  • pulmoza
  • OKY-046
  • ozagrel HCl
  • Molecular weight: 228.25
  • Formula: C13H12N2O2
  • CLOGP: 1.60
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 55.12
  • ALOGS: -2.73
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D002317 Cardiovascular Agents
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D005343 Fibrinolytic Agents
MeSH PA D006401 Hematologic Agents
MeSH PA D018494 Histamine Agents
MeSH PA D006633 Histamine Antagonists
MeSH PA D018377 Neurotransmitter Agents

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Spasm of cerebral arteries indication 73173006
Asthma indication 195967001 DOID:2841

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.37 acidic
pKa2 6.36 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Thromboxane-A synthase Enzyme IC50 7.96 CHEMBL
Thromboxane-A synthase Enzyme IC50 6.70 CHEMBL

External reference:

IDSource
D01683 KEGG_DRUG
4X5577N3ET UNII
189224-26-8 SECONDARY_CAS_RN
5282440 PUBCHEM_CID
CHEBI:134938 CHEBI
CHEMBL11662 ChEMBL_ID
5918 INN_ID
DB12017 DRUGBANK_ID
C034364 MESH_SUPPLEMENTAL_RECORD_UI
9866 IUPHAR_LIGAND_ID

Pharmaceutical products:

None