octodrine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
sympathomimetics 1978 543-82-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • octodrine
  • amidrine
  • isoctaminum
  • octodrin
  • vaporpac
1,3-dimethylamylamine (1,3-DMAA) analog
  • Molecular weight: 129.25
  • Formula: C8H19N
  • CLOGP: 2.69
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 1
  • TPSA: 26.02
  • ALOGS: -2.14
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Migraine off-label use 37796009 DOID:6364
Vascular headache off-label use 128187005
Tension-type headache off-label use 398057008
Alcoholism contraindication 7200002
Glaucoma contraindication 23986001 DOID:1686
Acute cerebrovascular insufficiency contraindication 29322000
Hypertensive disorder contraindication 38341003 DOID:10763
Acute nephropathy contraindication 58574008
Hepatic failure contraindication 59927004
Poisoning by acetaminophen contraindication 70273001
Disease of liver contraindication 235856003 DOID:409
Peripheral vascular disease contraindication 400047006
Organic Cardiac Disease contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.49 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D05228 KEGG_DRUG
C0772192 UMLSCUI
CHEBI:134758 CHEBI
CHEMBL2105833 ChEMBL_ID
10982 PUBCHEM_CID
2474 INN_ID
C000632592 MESH_SUPPLEMENTAL_RECORD_UI
3GQ9E911BI UNII
215217 RXNORM
4500 MMSL
007042 NDDF

Pharmaceutical products:

None