nipradilol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
vasodilators 1940 81486-22-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • nipradilol
  • nipradolol
  • hypadil
  • Molecular weight: 326.35
  • Formula: C15H22N2O6
  • CLOGP: 2.02
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 2
  • TPSA: 105.77
  • ALOGS: -2.89
  • ROTB: 8

Drug dosage:

None

ADMET properties:

PropertyValueReference
BA (Bioavailability) 0.35 % Kawashima H, Watanabe R, Esaki T, Kuroda M, Nagao C, Natsume-Kitatani Y, Ohashi R, Komura H, Mizuguchi K

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D018663 Adrenergic Agents
MeSH PA D000317 Adrenergic alpha-Antagonists
MeSH PA D018674 Adrenergic Antagonists
MeSH PA D000319 Adrenergic beta-Antagonists
MeSH PA D000959 Antihypertensive Agents
MeSH PA D002317 Cardiovascular Agents
MeSH PA D018377 Neurotransmitter Agents
MeSH PA D014665 Vasodilator Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.19 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
FVM336I71Y UNII
D01691 KEGG_DRUG
C0132531 UMLSCUI
CHEBI:31682 CHEBI
CHEMBL155622 ChEMBL_ID
72006 PUBCHEM_CID
5348 INN_ID
C036089 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None