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nimorazole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| antiprotozoals and radiosensitizers, metronidazole derivatives | 1938 | 6506-37-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An antitrichomonal agent which is effective either topically or orally and whose urinary metabolites are also trichomonicidal.
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 2 | g | O |
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,AKT2,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,CHEK1,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK1,JAK2,MAP3K21,MAP3K7,MAPK7,MAPK9,MARK4,MET,MTOR,NTRK2,PAK4,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CD,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1 | 48 | |||
| kinase-selectivity-class | AXL,BRAF,CDK9,DDR1,DYRK1B,GRK2,GSK3B,MAP2K6,MAP3K21,MAPK7,PRKDC,SIK2,STK33,TEK,TTK | 15 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | P01AB06 | ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ANTIPROTOZOALS AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES Nitroimidazole derivatives |
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000977 | Antiparasitic Agents |
| MeSH PA | D000981 | Antiprotozoal Agents |
| MeSH PA | D000994 | Antitrichomonal Agents |
| CHEBI has role | CHEBI:35610 | antineoplastic agent |
| CHEBI has role | CHEBI:171664 | antiamoebic agent |
Related Drugs by ATC class:
P01AB Nitroimidazole derivatives 7 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 5.06 | Basic |
| pKa2 | 1.38 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| N0000167080 | NUI |
| D07352 | KEGG_DRUG |
| C0028095 | UMLSCUI |
| CHEBI:134929 | CHEBI |
| CHEMBL435966 | ChEMBL_ID |
| DB12172 | DRUGBANK_ID |
| D009554 | MESH_DESCRIPTOR_UI |
| 23009 | PUBCHEM_CID |
| 2736 | INN_ID |
| 469ULX0H4G | UNII |
| 7427 | RXNORM |
| 004011 | NDDF |
| 324945001 | SNOMEDCT_US |
| 418509004 | SNOMEDCT_US |
Pharmaceutical products:
None