nimorazole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antiprotozoals and radiosensitizers, metronidazole derivatives 1938 6506-37-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • nimorazole
  • naxofem
  • naxogin
  • nimorazol
  • nitrimidazine
  • nulogyl
An antitrichomonal agent which is effective either topically or orally and whose urinary metabolites are also trichomonicidal.
  • Molecular weight: 226.24
  • Formula: C9H14N4O3
  • CLOGP: -0.13
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 0
  • TPSA: 76.11
  • ALOGS: -1.37
  • ROTB: 4

Drug dosage:

DoseUnitRoute
2 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC P01AB06 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES
Nitroimidazole derivatives
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000977 Antiparasitic Agents
MeSH PA D000981 Antiprotozoal Agents
MeSH PA D000994 Antitrichomonal Agents

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 5.06 Basic
pKa2 1.38 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000167080 NUI
D07352 KEGG_DRUG
C0028095 UMLSCUI
CHEBI:134929 CHEBI
CHEMBL435966 ChEMBL_ID
DB12172 DRUGBANK_ID
D009554 MESH_DESCRIPTOR_UI
23009 PUBCHEM_CID
2736 INN_ID
469ULX0H4G UNII
7427 RXNORM
004011 NDDF
324945001 SNOMEDCT_US
418509004 SNOMEDCT_US

Pharmaceutical products:

None