motretinide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
retinol derivatives 1849 56281-36-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • motretinide
  • tasmadem
  • tasmaderm
  • molrelinid
exerts a therapeutic influence on chemically induced papillomas & carcinomas of the skin in mice; RN given refers to cpd without isomeric designation; structure
  • Molecular weight: 353.51
  • Formula: C23H31NO2
  • CLOGP: 6.16
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 1
  • TPSA: 38.33
  • ALOGS: -5.66
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D10AD05 DERMATOLOGICALS
ANTI-ACNE PREPARATIONS
ANTI-ACNE PREPARATIONS FOR TOPICAL USE
Retinoids for topical use in acne

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Acne vulgaris indication 88616000




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.23 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D05082 KEGG_DRUG
C0129022 UMLSCUI
CHEBI:135490 CHEBI
CHEMBL519260 ChEMBL_ID
DB13368 DRUGBANK_ID
C010832 MESH_SUPPLEMENTAL_RECORD_UI
6314185 PUBCHEM_CID
4233 INN_ID
W786807KL1 UNII

Pharmaceutical products:

None