moroxydine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
antivirals 1844 3731-59-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • moroxydine
  • virumin
  • vironil
  • moroxidine
  • moroxidine hydrochloride
  • moroxidine HCl
  • Molecular weight: 171.20
  • Formula: C6H13N5O
  • CLOGP: -3.49
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 4
  • TPSA: 98.22
  • ALOGS: -2.08
  • ROTB: 0

Drug dosage:

DoseUnitRoute
0.30 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AKT2,AKT3,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK1,JAK2,MAP2K6,MAP3K21,MAP3K7,MAPK7,MAPK9,MTOR,NTRK2,PAK4,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1 48
kinase-selectivity-class ACVR2B,AXL,BRAF,CAMK2D,CDK4,DDR1,EPHB4,GRK2,MAP3K21,MAPK7,PRKDC,SIK2,STK33,TEK,TTK 15
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J05AX01 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIVIRALS FOR SYSTEMIC USE
DIRECT ACTING ANTIVIRALS
Other antivirals
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000998 Antiviral Agents
CHEBI has role CHEBI:22587 antiviral agent

Related Drugs by ATC class:

J05AX Other antivirals 15 drugs
amenamevirbaloxavir marboxilbulevirtideenfuvirtidefavipiravirfostemsaviribalizumabinosine pranobexlenacapavirletermovirmaravirocmaribavir show all 15 →

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Influenza indication 6142004 DOID:8469




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.59 Basic
pKa2 2.62 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07250 KEGG_DRUG
C0066805 UMLSCUI
CHEBI:749837 CHEBI
CHEMBL1490434 ChEMBL_ID
DB13597 DRUGBANK_ID
71655 PUBCHEM_CID
1220 INN_ID
C005267 MESH_SUPPLEMENTAL_RECORD_UI
O611591WAH UNII
30227 RXNORM
006158 NDDF
703380003 SNOMEDCT_US
703382006 SNOMEDCT_US

Pharmaceutical products:

None