Stem definition | Drug id | CAS RN |
---|---|---|
leukotriene receptor antagonists | 1836 | 158966-92-8 |
Dose | Unit | Route |
---|---|---|
10 | mg | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0.20 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 0.28 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 62 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 0.15 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 0.68 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.00 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 5 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Feb. 20, 1998 | FDA | MERCK |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Asthma | 5205.44 | 10.20 | 3913 | 208958 | 123648 | 63152503 |
Wheezing | 2171.69 | 10.20 | 2098 | 210773 | 93497 | 63182654 |
Eosinophilic granulomatosis with polyangiitis | 1307.18 | 10.20 | 425 | 212446 | 1767 | 63274384 |
Obstructive airways disorder | 988.16 | 10.20 | 700 | 212171 | 19999 | 63256152 |
Cough | 935.30 | 10.20 | 2615 | 210256 | 290128 | 62986023 |
Dyspnoea | 926.28 | 10.20 | 4516 | 208355 | 656797 | 62619354 |
Sleep disorder due to a general medical condition | 726.60 | 10.20 | 473 | 212398 | 11715 | 63264436 |
Sputum discoloured | 703.05 | 10.20 | 519 | 212352 | 15828 | 63260323 |
Full blood count abnormal | 664.77 | 10.20 | 667 | 212204 | 31050 | 63245101 |
Productive cough | 618.93 | 10.20 | 903 | 211968 | 62305 | 63213846 |
Pemphigus | 587.82 | 10.20 | 5 | 212866 | 183721 | 63092430 |
Chest discomfort | 586.41 | 10.20 | 1200 | 211671 | 108769 | 63167382 |
Forced expiratory volume decreased | 541.13 | 10.20 | 285 | 212586 | 4683 | 63271468 |
Synovitis | 500.35 | 10.20 | 32 | 212839 | 186886 | 63089265 |
Hand deformity | 497.95 | 10.20 | 7 | 212864 | 159450 | 63116701 |
Systemic lupus erythematosus | 447.80 | 10.20 | 80 | 212791 | 208838 | 63067313 |
Glossodynia | 441.53 | 10.20 | 44 | 212827 | 178832 | 63097319 |
Rhinitis allergic | 432.99 | 10.20 | 340 | 212531 | 11387 | 63264764 |
Urticaria | 415.93 | 10.20 | 1362 | 211509 | 164440 | 63111711 |
Arthropathy | 384.55 | 10.20 | 153 | 212718 | 234639 | 63041512 |
Toxicity to various agents | 378.16 | 10.20 | 178 | 212693 | 247072 | 63029079 |
Bronchitis | 363.74 | 10.20 | 1081 | 211790 | 123854 | 63152297 |
Nasal congestion | 362.24 | 10.20 | 727 | 212144 | 64933 | 63211218 |
Pericarditis | 353.62 | 10.20 | 22 | 212849 | 131557 | 63144594 |
Contraindicated product administered | 352.86 | 10.20 | 144 | 212727 | 217504 | 63058647 |
Nasal polyps | 351.69 | 10.20 | 231 | 212640 | 5808 | 63270343 |
Sinusitis | 340.94 | 10.20 | 1584 | 211287 | 225069 | 63051082 |
Impaired quality of life | 339.82 | 10.20 | 317 | 212554 | 13466 | 63262685 |
Upper respiratory tract infection | 336.19 | 10.20 | 806 | 212065 | 81241 | 63194910 |
Drug intolerance | 314.25 | 10.20 | 343 | 212528 | 308318 | 62967833 |
Chronic obstructive pulmonary disease | 310.48 | 10.20 | 664 | 212207 | 62022 | 63214129 |
Treatment failure | 303.18 | 10.20 | 144 | 212727 | 198899 | 63077252 |
Joint swelling | 297.67 | 10.20 | 398 | 212473 | 327268 | 62948883 |
Food allergy | 294.22 | 10.20 | 269 | 212602 | 11132 | 63265019 |
Wound | 286.51 | 10.20 | 95 | 212776 | 163168 | 63112983 |
Alopecia | 280.98 | 10.20 | 436 | 212435 | 337100 | 62939051 |
Gastrooesophageal reflux disease | 279.68 | 10.20 | 829 | 212042 | 94810 | 63181341 |
Blood immunoglobulin E increased | 270.98 | 10.20 | 166 | 212705 | 3683 | 63272468 |
Rheumatoid factor positive | 262.15 | 10.20 | 4 | 212867 | 84402 | 63191749 |
Therapeutic product effect decreased | 257.64 | 10.20 | 165 | 212706 | 193022 | 63083129 |
Helicobacter infection | 257.03 | 10.20 | 13 | 212858 | 92772 | 63183379 |
Off label use | 254.63 | 10.20 | 1281 | 211590 | 673181 | 62602970 |
Sleep apnoea syndrome | 253.38 | 10.20 | 394 | 212477 | 28739 | 63247412 |
Pneumonia | 251.96 | 10.20 | 2486 | 210385 | 454281 | 62821870 |
Middle insomnia | 248.65 | 10.20 | 257 | 212614 | 12386 | 63263765 |
Asthmatic crisis | 244.03 | 10.20 | 120 | 212751 | 1693 | 63274458 |
Seasonal allergy | 240.19 | 10.20 | 323 | 212548 | 20627 | 63255524 |
Maternal exposure during pregnancy | 230.01 | 10.20 | 239 | 212632 | 219823 | 63056328 |
Breath sounds abnormal | 228.43 | 10.20 | 230 | 212641 | 10743 | 63265408 |
Polycystic ovaries | 226.80 | 10.20 | 157 | 212714 | 4314 | 63271837 |
Upper-airway cough syndrome | 218.98 | 10.20 | 229 | 212642 | 11189 | 63264962 |
Nightmare | 218.64 | 10.20 | 295 | 212576 | 18899 | 63257252 |
Dermatitis atopic | 217.58 | 10.20 | 212 | 212659 | 9512 | 63266639 |
Temperature regulation disorder | 216.10 | 10.20 | 173 | 212698 | 5959 | 63270192 |
Therapeutic product effect incomplete | 214.21 | 10.20 | 909 | 211962 | 124147 | 63152004 |
Respiratory tract infection | 214.16 | 10.20 | 447 | 212424 | 41036 | 63235115 |
Infusion related reaction | 214.02 | 10.20 | 307 | 212564 | 245214 | 63030937 |
Eosinophil count increased | 212.86 | 10.20 | 221 | 212650 | 10707 | 63265444 |
Anaphylactic reaction | 211.60 | 10.20 | 592 | 212279 | 65508 | 63210643 |
Dyspnoea exertional | 210.95 | 10.20 | 558 | 212313 | 59744 | 63216407 |
Abdominal discomfort | 205.29 | 10.20 | 485 | 212386 | 320400 | 62955751 |
Muscle injury | 203.33 | 10.20 | 3 | 212868 | 65342 | 63210809 |
Neutropenia | 201.66 | 10.20 | 174 | 212697 | 174831 | 63101320 |
Folliculitis | 200.82 | 10.20 | 8 | 212863 | 70309 | 63205842 |
Influenza | 193.78 | 10.20 | 800 | 212071 | 107922 | 63168229 |
Product dose omission issue | 189.59 | 10.20 | 1390 | 211481 | 232923 | 63043228 |
Acute kidney injury | 186.72 | 10.20 | 376 | 212495 | 263039 | 63013112 |
Sensitisation | 186.24 | 10.20 | 125 | 212746 | 3261 | 63272890 |
Completed suicide | 177.56 | 10.20 | 137 | 212734 | 145536 | 63130615 |
Impaired healing | 175.79 | 10.20 | 62 | 212809 | 102480 | 63173671 |
Rhinorrhoea | 173.49 | 10.20 | 549 | 212322 | 65028 | 63211123 |
Loss of personal independence in daily activities | 171.10 | 10.20 | 713 | 212158 | 96577 | 63179574 |
Stomatitis | 170.95 | 10.20 | 129 | 212742 | 138596 | 63137555 |
Secretion discharge | 169.19 | 10.20 | 207 | 212664 | 12024 | 63264127 |
Blood test abnormal | 168.63 | 10.20 | 234 | 212637 | 15395 | 63260756 |
General physical health deterioration | 162.79 | 10.20 | 265 | 212606 | 201137 | 63075014 |
Malignant neoplasm progression | 154.50 | 10.20 | 42 | 212829 | 82079 | 63194072 |
Coeliac disease | 150.82 | 10.20 | 200 | 212671 | 12597 | 63263554 |
Pancytopenia | 149.23 | 10.20 | 69 | 212802 | 96864 | 63179287 |
Product quality issue | 147.52 | 10.20 | 353 | 212518 | 35512 | 63240639 |
Infective pulmonary exacerbation of cystic fibrosis | 146.60 | 10.20 | 164 | 212707 | 8653 | 63267498 |
Eczema | 145.05 | 10.20 | 329 | 212542 | 31962 | 63244189 |
Anaemia | 144.61 | 10.20 | 502 | 212369 | 292928 | 62983223 |
Ejection fraction | 142.45 | 10.20 | 93 | 212778 | 2313 | 63273838 |
Eosinophilia | 140.08 | 10.20 | 264 | 212607 | 22492 | 63253659 |
Blister | 135.52 | 10.20 | 141 | 212730 | 129673 | 63146478 |
Suicidal ideation | 133.76 | 10.20 | 487 | 212384 | 61934 | 63214217 |
Swelling | 133.74 | 10.20 | 474 | 212397 | 274904 | 63001247 |
Bronchospasm | 132.87 | 10.20 | 221 | 212650 | 17059 | 63259092 |
Drug interaction | 131.25 | 10.20 | 366 | 212505 | 228765 | 63047386 |
Vital capacity decreased | 130.60 | 10.20 | 78 | 212793 | 1650 | 63274501 |
Death | 130.21 | 10.20 | 730 | 212141 | 373651 | 62902500 |
Rheumatic fever | 129.97 | 10.20 | 3 | 212868 | 43108 | 63233043 |
Pulmonary function test abnormal | 129.02 | 10.20 | 79 | 212792 | 1751 | 63274400 |
Reversible airways obstruction | 128.54 | 10.20 | 79 | 212792 | 1763 | 63274388 |
Drug abuse | 125.74 | 10.20 | 43 | 212828 | 72475 | 63203676 |
Rhinitis | 125.36 | 10.20 | 172 | 212699 | 11194 | 63264957 |
Intentional product use issue | 124.62 | 10.20 | 147 | 212724 | 127745 | 63148406 |
Illness | 123.65 | 10.20 | 404 | 212467 | 48655 | 63227496 |
Musculoskeletal stiffness | 123.62 | 10.20 | 272 | 212599 | 184346 | 63091805 |
Disease progression | 122.97 | 10.20 | 138 | 212733 | 122620 | 63153531 |
Total lung capacity increased | 121.62 | 10.20 | 83 | 212788 | 2227 | 63273924 |
Febrile neutropenia | 121.02 | 10.20 | 131 | 212740 | 118318 | 63157833 |
Sneezing | 120.50 | 10.20 | 218 | 212653 | 18000 | 63258151 |
C-reactive protein abnormal | 120.01 | 10.20 | 9 | 212862 | 46087 | 63230064 |
Liver injury | 119.53 | 10.20 | 28 | 212843 | 60492 | 63215659 |
Rheumatoid arthritis | 118.54 | 10.20 | 444 | 212427 | 253375 | 63022776 |
Oropharyngeal pain | 117.38 | 10.20 | 626 | 212245 | 93861 | 63182290 |
Discomfort | 116.72 | 10.20 | 241 | 212630 | 167133 | 63109018 |
Headache | 114.68 | 10.20 | 2854 | 210017 | 630387 | 62645764 |
Dysphonia | 113.68 | 10.20 | 385 | 212486 | 47229 | 63228922 |
Aggression | 112.95 | 10.20 | 246 | 212625 | 23252 | 63252899 |
Thrombocytopenia | 112.00 | 10.20 | 210 | 212661 | 150947 | 63125204 |
Throat clearing | 111.23 | 10.20 | 80 | 212791 | 2339 | 63273812 |
C-reactive protein increased | 110.46 | 10.20 | 93 | 212778 | 94614 | 63181537 |
Respiratory tract congestion | 109.91 | 10.20 | 207 | 212664 | 17625 | 63258526 |
Neuropsychiatric symptoms | 109.55 | 10.20 | 53 | 212818 | 720 | 63275431 |
Drug ineffective | 109.08 | 10.20 | 2672 | 210199 | 1042093 | 62234058 |
Nasal oedema | 108.06 | 10.20 | 66 | 212805 | 1456 | 63274695 |
Bronchial secretion retention | 108.01 | 10.20 | 83 | 212788 | 2690 | 63273461 |
Sputum increased | 107.79 | 10.20 | 79 | 212792 | 2380 | 63273771 |
Anxiety | 107.56 | 10.20 | 1159 | 211712 | 216382 | 63059769 |
Pruritus | 107.43 | 10.20 | 1755 | 211116 | 359698 | 62916453 |
Sinus disorder | 105.68 | 10.20 | 246 | 212625 | 24307 | 63251844 |
Confusional state | 105.54 | 10.20 | 421 | 212450 | 235959 | 63040192 |
Eye pruritus | 104.41 | 10.20 | 208 | 212663 | 18463 | 63257688 |
Hyponatraemia | 103.36 | 10.20 | 134 | 212737 | 111766 | 63164385 |
Multiple allergies | 102.76 | 10.20 | 174 | 212697 | 13628 | 63262523 |
Perfume sensitivity | 101.59 | 10.20 | 51 | 212820 | 754 | 63275397 |
Peak expiratory flow rate decreased | 101.00 | 10.20 | 47 | 212824 | 582 | 63275569 |
Rales | 99.79 | 10.20 | 164 | 212707 | 12533 | 63263618 |
Lung hyperinflation | 99.29 | 10.20 | 59 | 212812 | 1236 | 63274915 |
Immunodeficiency | 98.44 | 10.20 | 213 | 212658 | 20041 | 63256110 |
Sleep disorder due to general medical condition, insomnia type | 97.66 | 10.20 | 27 | 212844 | 52190 | 63223961 |
Irritable bowel syndrome | 97.25 | 10.20 | 80 | 212791 | 82332 | 63193819 |
Gastrointestinal disorder | 95.75 | 10.20 | 184 | 212687 | 131055 | 63145096 |
Hepatic enzyme increased | 94.38 | 10.20 | 354 | 212517 | 201974 | 63074177 |
Heart rate increased | 93.34 | 10.20 | 588 | 212283 | 93650 | 63182501 |
Angioedema | 92.63 | 10.20 | 362 | 212509 | 47603 | 63228548 |
Status asthmaticus | 90.40 | 10.20 | 49 | 212822 | 855 | 63275296 |
Sensitivity to weather change | 89.77 | 10.20 | 116 | 212755 | 7121 | 63269030 |
Hypotension | 89.10 | 10.20 | 542 | 212329 | 272062 | 63004089 |
Multiple organ dysfunction syndrome | 87.95 | 10.20 | 40 | 212831 | 56712 | 63219439 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 87.61 | 10.20 | 65 | 212806 | 1996 | 63274155 |
Forced vital capacity decreased | 87.57 | 10.20 | 51 | 212820 | 1028 | 63275123 |
Dust allergy | 87.08 | 10.20 | 44 | 212827 | 660 | 63275491 |
Mucosal inflammation | 86.40 | 10.20 | 25 | 212846 | 46903 | 63229248 |
Ear pruritus | 86.01 | 10.20 | 85 | 212786 | 3880 | 63272271 |
Sleep terror | 84.76 | 10.20 | 71 | 212800 | 2609 | 63273542 |
Diarrhoea | 82.37 | 10.20 | 1801 | 211070 | 713565 | 62562586 |
Leukopenia | 81.72 | 10.20 | 83 | 212788 | 77207 | 63198944 |
Intentional overdose | 81.44 | 10.20 | 77 | 212794 | 74075 | 63202076 |
Rash erythematous | 81.41 | 10.20 | 320 | 212551 | 42190 | 63233961 |
Chronic spontaneous urticaria | 79.16 | 10.20 | 49 | 212822 | 1108 | 63275043 |
Abnormal behaviour | 78.72 | 10.20 | 202 | 212669 | 21224 | 63254927 |
Respiratory rate increased | 78.67 | 10.20 | 154 | 212717 | 13494 | 63262657 |
Respiration abnormal | 78.26 | 10.20 | 102 | 212769 | 6315 | 63269836 |
Pulmonary mass | 76.86 | 10.20 | 207 | 212664 | 22389 | 63253762 |
Rhonchi | 76.86 | 10.20 | 66 | 212805 | 2510 | 63273641 |
Renal impairment | 76.36 | 10.20 | 111 | 212760 | 88244 | 63187907 |
Carpal tunnel syndrome | 75.18 | 10.20 | 195 | 212676 | 20622 | 63255529 |
Emphysema | 75.04 | 10.20 | 133 | 212738 | 10805 | 63265346 |
Allergy to animal | 73.37 | 10.20 | 48 | 212823 | 1198 | 63274953 |
Respiratory symptom | 73.06 | 10.20 | 72 | 212799 | 3275 | 63272876 |
Sinus congestion | 73.04 | 10.20 | 177 | 212694 | 17946 | 63258205 |
Toxic epidermal necrolysis | 71.93 | 10.20 | 3 | 212868 | 25331 | 63250820 |
Sputum culture positive | 71.84 | 10.20 | 59 | 212812 | 2108 | 63274043 |
COVID-19 | 71.72 | 10.20 | 635 | 212236 | 112468 | 63163683 |
Red blood cell sedimentation rate increased | 71.34 | 10.20 | 29 | 212842 | 43953 | 63232198 |
Mobility decreased | 71.20 | 10.20 | 191 | 212680 | 120968 | 63155183 |
Septic shock | 71.07 | 10.20 | 71 | 212800 | 66558 | 63209593 |
Restrictive pulmonary disease | 70.51 | 10.20 | 54 | 212817 | 1741 | 63274410 |
Throat tightness | 69.16 | 10.20 | 212 | 212659 | 24675 | 63251476 |
Bronchiectasis | 68.67 | 10.20 | 161 | 212710 | 15981 | 63260170 |
Pulmonary function test decreased | 68.35 | 10.20 | 75 | 212796 | 3872 | 63272279 |
Bradycardia | 68.32 | 10.20 | 87 | 212784 | 73140 | 63203011 |
Nasal obstruction | 67.83 | 10.20 | 52 | 212819 | 1679 | 63274472 |
Sinusitis fungal | 67.39 | 10.20 | 53 | 212818 | 1778 | 63274373 |
Hypokalaemia | 66.14 | 10.20 | 157 | 212714 | 103647 | 63172504 |
Chronic sinusitis | 65.80 | 10.20 | 138 | 212733 | 12705 | 63263446 |
Hip arthroplasty | 65.79 | 10.20 | 39 | 212832 | 47607 | 63228544 |
Poor quality device used | 65.77 | 10.20 | 55 | 212816 | 2016 | 63274135 |
Bronchial obstruction | 65.12 | 10.20 | 48 | 212823 | 1459 | 63274692 |
Bronchial disorder | 64.73 | 10.20 | 45 | 212826 | 1245 | 63274906 |
Nasal discharge discolouration | 63.36 | 10.20 | 56 | 212815 | 2215 | 63273936 |
Depressed level of consciousness | 63.00 | 10.20 | 69 | 212802 | 62009 | 63214142 |
Crying | 62.23 | 10.20 | 196 | 212675 | 23147 | 63253004 |
Coma | 61.59 | 10.20 | 75 | 212796 | 64289 | 63211862 |
Asthma exercise induced | 61.32 | 10.20 | 27 | 212844 | 291 | 63275860 |
Haemoglobin decreased | 61.22 | 10.20 | 265 | 212606 | 145220 | 63130931 |
Bone marrow failure | 61.00 | 10.20 | 12 | 212859 | 29278 | 63246873 |
Vocal cord dysfunction | 60.79 | 10.20 | 32 | 212839 | 525 | 63275626 |
Throat irritation | 59.30 | 10.20 | 267 | 212604 | 37380 | 63238771 |
Factor V Leiden mutation | 59.18 | 10.20 | 24 | 212847 | 207 | 63275944 |
Live birth | 58.96 | 10.20 | 8 | 212863 | 25622 | 63250529 |
Blood pressure systolic increased | 58.81 | 10.20 | 314 | 212557 | 47083 | 63229068 |
Insomnia | 58.65 | 10.20 | 1031 | 211840 | 214221 | 63061930 |
Abnormal dreams | 58.61 | 10.20 | 117 | 212754 | 10399 | 63265752 |
Bronchial neoplasm | 58.21 | 10.20 | 30 | 212841 | 470 | 63275681 |
Urticaria chronic | 58.16 | 10.20 | 33 | 212838 | 632 | 63275519 |
Ejection fraction abnormal | 57.92 | 10.20 | 48 | 212823 | 1737 | 63274414 |
Cystic fibrosis | 57.72 | 10.20 | 63 | 212808 | 3233 | 63272918 |
Hyper IgE syndrome | 57.65 | 10.20 | 30 | 212841 | 480 | 63275671 |
Therapy non-responder | 57.48 | 10.20 | 104 | 212767 | 75797 | 63200354 |
Infusion site erythema | 56.96 | 10.20 | 123 | 212748 | 11556 | 63264595 |
Inflammation | 56.86 | 10.20 | 119 | 212752 | 82154 | 63193997 |
Blood pressure increased | 56.52 | 10.20 | 809 | 212062 | 161253 | 63114898 |
Nasal turbinate hypertrophy | 56.52 | 10.20 | 34 | 212837 | 729 | 63275422 |
Infusion site swelling | 54.81 | 10.20 | 109 | 212762 | 9661 | 63266490 |
Burning sensation | 54.80 | 10.20 | 341 | 212530 | 54066 | 63222085 |
Salpingo-oophorectomy unilateral | 54.48 | 10.20 | 35 | 212836 | 846 | 63275305 |
Product use issue | 54.36 | 10.20 | 475 | 212396 | 220045 | 63056106 |
Liver disorder | 54.12 | 10.20 | 60 | 212811 | 53627 | 63222524 |
Nephrectomy | 54.11 | 10.20 | 43 | 212828 | 1465 | 63274686 |
Haemoptysis | 54.00 | 10.20 | 215 | 212656 | 28511 | 63247640 |
Arthralgia | 53.76 | 10.20 | 1477 | 211394 | 568233 | 62707918 |
Bronchial haemorrhage | 53.46 | 10.20 | 30 | 212841 | 562 | 63275589 |
Alanine aminotransferase increased | 53.43 | 10.20 | 174 | 212697 | 103596 | 63172555 |
Blood cholesterol increased | 53.18 | 10.20 | 151 | 212720 | 93881 | 63182270 |
Mood altered | 53.13 | 10.20 | 138 | 212733 | 14605 | 63261546 |
Viral infection | 52.53 | 10.20 | 248 | 212623 | 35415 | 63240736 |
Malaise | 52.26 | 10.20 | 1792 | 211079 | 414162 | 62861989 |
Decreased appetite | 52.09 | 10.20 | 564 | 212307 | 250488 | 63025663 |
Bronchopulmonary aspergillosis allergic | 51.96 | 10.20 | 50 | 212821 | 2208 | 63273943 |
Poor quality sleep | 51.87 | 10.20 | 166 | 212705 | 19769 | 63256382 |
Humidity intolerance | 51.84 | 10.20 | 25 | 212846 | 337 | 63275814 |
Metabolic acidosis | 51.63 | 10.20 | 45 | 212826 | 45024 | 63231127 |
Infusion site pruritus | 51.60 | 10.20 | 81 | 212790 | 5954 | 63270197 |
Ascites | 51.26 | 10.20 | 37 | 212834 | 40691 | 63235460 |
Hyperkalaemia | 50.97 | 10.20 | 64 | 212807 | 54139 | 63222012 |
Depression | 50.64 | 10.20 | 933 | 211938 | 195559 | 63080592 |
Frustration tolerance decreased | 50.57 | 10.20 | 87 | 212784 | 6901 | 63269250 |
Migraine | 50.25 | 10.20 | 549 | 212322 | 102797 | 63173354 |
Platelet count decreased | 49.77 | 10.20 | 210 | 212661 | 115912 | 63160239 |
Sepsis | 49.68 | 10.20 | 305 | 212566 | 152818 | 63123333 |
Body tinea | 49.66 | 10.20 | 45 | 212826 | 1840 | 63274311 |
Total lung capacity decreased | 49.60 | 10.20 | 48 | 212823 | 2135 | 63274016 |
Anger | 49.49 | 10.20 | 121 | 212750 | 12335 | 63263816 |
Sarcoidosis | 49.37 | 10.20 | 87 | 212784 | 7035 | 63269116 |
Aspirin-exacerbated respiratory disease | 49.12 | 10.20 | 33 | 212838 | 862 | 63275289 |
Lacrimation increased | 48.51 | 10.20 | 166 | 212705 | 20465 | 63255686 |
Hereditary angioedema | 48.12 | 10.20 | 89 | 212782 | 7473 | 63268678 |
Respiratory disorder | 47.86 | 10.20 | 258 | 212613 | 38824 | 63237327 |
Idiopathic intracranial hypertension | 47.84 | 10.20 | 54 | 212817 | 2877 | 63273274 |
Prolonged expiration | 47.56 | 10.20 | 35 | 212836 | 1061 | 63275090 |
Nasopharyngitis | 47.26 | 10.20 | 1151 | 211720 | 253106 | 63023045 |
Knee arthroplasty | 46.93 | 10.20 | 68 | 212803 | 54138 | 63222013 |
Aphonia | 46.83 | 10.20 | 104 | 212767 | 9959 | 63266192 |
Psoriatic arthropathy | 46.74 | 10.20 | 154 | 212717 | 91366 | 63184785 |
Drug tolerance decreased | 46.68 | 10.20 | 3 | 212868 | 17470 | 63258681 |
Ear infection | 46.62 | 10.20 | 252 | 212619 | 37961 | 63238190 |
Scratch | 46.55 | 10.20 | 81 | 212790 | 6484 | 63269667 |
Inappropriate schedule of product administration | 46.35 | 10.20 | 543 | 212328 | 103422 | 63172729 |
Sopor | 46.32 | 10.20 | 9 | 212862 | 22155 | 63253996 |
Infusion site pain | 46.22 | 10.20 | 143 | 212728 | 16726 | 63259425 |
Neoplasm progression | 45.97 | 10.20 | 33 | 212838 | 36395 | 63239756 |
Smoke sensitivity | 45.88 | 10.20 | 25 | 212846 | 441 | 63275710 |
Cardio-respiratory arrest | 45.53 | 10.20 | 82 | 212789 | 59877 | 63216274 |
Feeling abnormal | 45.24 | 10.20 | 724 | 212147 | 147668 | 63128483 |
Metastases to bone | 45.08 | 10.20 | 8 | 212863 | 21011 | 63255140 |
Bone erosion | 44.62 | 10.20 | 4 | 212867 | 17713 | 63258438 |
Mast cell activation syndrome | 44.28 | 10.20 | 30 | 212841 | 795 | 63275356 |
Fluid retention | 44.16 | 10.20 | 347 | 212524 | 59339 | 63216812 |
Cardiac failure | 44.16 | 10.20 | 152 | 212719 | 88990 | 63187161 |
Inhibitory drug interaction | 43.98 | 10.20 | 51 | 212820 | 2798 | 63273353 |
Hypoventilation | 43.72 | 10.20 | 66 | 212805 | 4688 | 63271463 |
FEV1/FVC ratio decreased | 42.82 | 10.20 | 16 | 212855 | 108 | 63276043 |
Metastases to liver | 42.77 | 10.20 | 13 | 212858 | 23626 | 63252525 |
Cardiac disorder | 42.44 | 10.20 | 304 | 212567 | 50512 | 63225639 |
Skin plaque | 42.16 | 10.20 | 89 | 212782 | 8231 | 63267920 |
White blood cell count decreased | 41.59 | 10.20 | 284 | 212587 | 138820 | 63137331 |
Glucose tolerance impaired | 41.34 | 10.20 | 77 | 212794 | 6500 | 63269651 |
Bursitis | 41.03 | 10.20 | 238 | 212633 | 36803 | 63239348 |
Palmar-plantar erythrodysaesthesia syndrome | 41.02 | 10.20 | 13 | 212858 | 23002 | 63253149 |
Aspartate aminotransferase increased | 40.73 | 10.20 | 160 | 212711 | 90117 | 63186034 |
Increased bronchial secretion | 40.44 | 10.20 | 39 | 212832 | 1727 | 63274424 |
Oral allergy syndrome | 40.37 | 10.20 | 13 | 212858 | 52 | 63276099 |
Creatinine renal clearance decreased | 40.22 | 10.20 | 4 | 212867 | 16304 | 63259847 |
Agranulocytosis | 40.07 | 10.20 | 17 | 212854 | 25117 | 63251034 |
Neurotoxicity | 39.81 | 10.20 | 5 | 212866 | 16985 | 63259166 |
Lung opacity | 39.64 | 10.20 | 51 | 212820 | 3117 | 63273034 |
Atopy | 39.54 | 10.20 | 19 | 212852 | 254 | 63275897 |
Tic | 39.48 | 10.20 | 36 | 212835 | 1484 | 63274667 |
Lactic acidosis | 39.46 | 10.20 | 42 | 212829 | 38245 | 63237906 |
Delirium | 39.39 | 10.20 | 68 | 212803 | 50473 | 63225678 |
Cytomegalovirus infection | 38.86 | 10.20 | 11 | 212860 | 20941 | 63255210 |
Cardiac murmur | 38.61 | 10.20 | 122 | 212749 | 14430 | 63261721 |
Erythema | 38.05 | 10.20 | 813 | 212058 | 174938 | 63101213 |
Mastocytosis | 38.03 | 10.20 | 24 | 212847 | 562 | 63275589 |
Bronchial wall thickening | 37.95 | 10.20 | 35 | 212836 | 1464 | 63274687 |
Endometrial ablation | 37.86 | 10.20 | 29 | 212842 | 935 | 63275216 |
Mite allergy | 37.83 | 10.20 | 25 | 212846 | 635 | 63275516 |
Product use in unapproved indication | 37.68 | 10.20 | 825 | 212046 | 178255 | 63097896 |
Respiratory tract inflammation | 37.36 | 10.20 | 24 | 212847 | 580 | 63275571 |
Cholecystitis chronic | 37.35 | 10.20 | 97 | 212774 | 10264 | 63265887 |
Mood swings | 37.09 | 10.20 | 140 | 212731 | 18108 | 63258043 |
Swelling face | 36.98 | 10.20 | 350 | 212521 | 63125 | 63213026 |
Hepatocellular injury | 36.98 | 10.20 | 23 | 212848 | 27358 | 63248793 |
Infusion site extravasation | 36.96 | 10.20 | 97 | 212774 | 10329 | 63265822 |
Infection susceptibility increased | 36.91 | 10.20 | 52 | 212819 | 3469 | 63272682 |
Cholestasis | 36.71 | 10.20 | 27 | 212844 | 29407 | 63246744 |
Gastrointestinal haemorrhage | 36.54 | 10.20 | 144 | 212727 | 81032 | 63195119 |
Eosinophilic pneumonia | 36.54 | 10.20 | 41 | 212830 | 2170 | 63273981 |
Joint range of motion decreased | 36.39 | 10.20 | 33 | 212838 | 32395 | 63243756 |
Cardiac arrest | 36.27 | 10.20 | 173 | 212698 | 92372 | 63183779 |
Prescribed underdose | 36.04 | 10.20 | 28 | 212843 | 29661 | 63246490 |
Encephalopathy | 35.90 | 10.20 | 46 | 212825 | 38574 | 63237577 |
Lipohypertrophy | 35.26 | 10.20 | 24 | 212847 | 641 | 63275510 |
Pain | 35.24 | 10.20 | 2079 | 210792 | 738549 | 62537602 |
Embolism venous | 35.19 | 10.20 | 48 | 212823 | 3106 | 63273045 |
Infusion site haemorrhage | 35.09 | 10.20 | 62 | 212809 | 5024 | 63271127 |
Heart sounds | 34.88 | 10.20 | 28 | 212843 | 968 | 63275183 |
Peripheral swelling | 34.76 | 10.20 | 655 | 212216 | 265287 | 63010864 |
Neutrophil count decreased | 34.59 | 10.20 | 87 | 212784 | 56319 | 63219832 |
Dehydration | 34.13 | 10.20 | 394 | 212477 | 172960 | 63103191 |
Bronchitis chronic | 33.90 | 10.20 | 56 | 212815 | 4297 | 63271854 |
Hypomagnesaemia | 33.76 | 10.20 | 28 | 212843 | 28709 | 63247442 |
Sleep disorder | 33.72 | 10.20 | 420 | 212451 | 81146 | 63195005 |
Acute myeloid leukaemia | 33.72 | 10.20 | 8 | 212863 | 17139 | 63259012 |
Eosinophil count abnormal | 33.04 | 10.20 | 22 | 212849 | 566 | 63275585 |
Pulmonary pain | 32.88 | 10.20 | 49 | 212822 | 3441 | 63272710 |
Affective disorder | 32.61 | 10.20 | 67 | 212804 | 6079 | 63270072 |
Spirometry abnormal | 32.58 | 10.20 | 16 | 212855 | 225 | 63275926 |
Skin ulcer | 32.57 | 10.20 | 59 | 212812 | 42986 | 63233165 |
Hypocalcaemia | 32.45 | 10.20 | 35 | 212836 | 31678 | 63244473 |
Infection | 32.29 | 10.20 | 557 | 212314 | 228616 | 63047535 |
Stress | 32.27 | 10.20 | 356 | 212515 | 66811 | 63209340 |
Occupational asthma | 32.20 | 10.20 | 14 | 212857 | 146 | 63276005 |
Chest X-ray abnormal | 32.09 | 10.20 | 56 | 212815 | 4493 | 63271658 |
Colitis | 32.03 | 10.20 | 72 | 212799 | 48456 | 63227695 |
Neutropenic sepsis | 31.68 | 10.20 | 8 | 212863 | 16430 | 63259721 |
Biliary dyskinesia | 31.16 | 10.20 | 42 | 212829 | 2687 | 63273464 |
Interstitial lung disease | 31.04 | 10.20 | 105 | 212766 | 61803 | 63214348 |
Condition aggravated | 30.94 | 10.20 | 1071 | 211800 | 401146 | 62875005 |
Rhabdomyolysis | 30.84 | 10.20 | 63 | 212808 | 43888 | 63232263 |
Drug level increased | 30.84 | 10.20 | 19 | 212852 | 22717 | 63253434 |
Orthostatic hypotension | 30.67 | 10.20 | 46 | 212825 | 36114 | 63240037 |
Pneumothorax spontaneous | 30.39 | 10.20 | 24 | 212847 | 810 | 63275341 |
Irritability | 30.27 | 10.20 | 196 | 212675 | 31498 | 63244653 |
Psoriasis | 30.25 | 10.20 | 434 | 212437 | 86523 | 63189628 |
Circulatory collapse | 30.23 | 10.20 | 18 | 212853 | 21920 | 63254231 |
Respiratory gas exchange disorder | 30.17 | 10.20 | 18 | 212853 | 380 | 63275771 |
Blood creatinine increased | 30.05 | 10.20 | 172 | 212699 | 87672 | 63188479 |
Oxygen saturation decreased | 29.98 | 10.20 | 440 | 212431 | 88145 | 63188006 |
Renal disorder | 29.73 | 10.20 | 201 | 212670 | 32773 | 63243378 |
Rash | 29.64 | 10.20 | 1558 | 211313 | 559313 | 62716838 |
Renal failure | 29.59 | 10.20 | 252 | 212619 | 117400 | 63158751 |
Blood creatine phosphokinase increased | 29.59 | 10.20 | 35 | 212836 | 30395 | 63245756 |
Osteonecrosis of jaw | 29.49 | 10.20 | 45 | 212826 | 35078 | 63241073 |
Premature delivery | 29.26 | 10.20 | 35 | 212836 | 30246 | 63245905 |
Lymphocyte count decreased | 29.21 | 10.20 | 35 | 212836 | 30222 | 63245929 |
Dysphemia | 28.78 | 10.20 | 40 | 212831 | 2635 | 63273516 |
Anuria | 28.67 | 10.20 | 4 | 212867 | 12547 | 63263604 |
Disseminated intravascular coagulation | 28.63 | 10.20 | 14 | 212857 | 19037 | 63257114 |
Rash maculo-papular | 28.61 | 10.20 | 39 | 212832 | 31857 | 63244294 |
Pharyngeal oedema | 28.49 | 10.20 | 106 | 212765 | 13615 | 63262536 |
Blood lactic acid increased | 28.33 | 10.20 | 69 | 212802 | 7017 | 63269134 |
Gamma-glutamyltransferase increased | 28.19 | 10.20 | 44 | 212827 | 33987 | 63242164 |
Infusion site bruising | 28.12 | 10.20 | 48 | 212823 | 3784 | 63272367 |
Hypothyroidism | 27.85 | 10.20 | 241 | 212630 | 42391 | 63233760 |
Lip swelling | 27.79 | 10.20 | 189 | 212682 | 30874 | 63245277 |
Ankle fracture | 27.64 | 10.20 | 126 | 212745 | 17729 | 63258422 |
Facet joint syndrome | 27.42 | 10.20 | 4 | 212867 | 12134 | 63264017 |
Hysterectomy | 27.40 | 10.20 | 82 | 212789 | 9417 | 63266734 |
Neurosensory hypoacusis | 27.36 | 10.20 | 14 | 212857 | 216 | 63275935 |
Quality of life decreased | 27.32 | 10.20 | 78 | 212793 | 8725 | 63267426 |
Increased viscosity of bronchial secretion | 27.28 | 10.20 | 16 | 212855 | 327 | 63275824 |
Vomiting | 27.25 | 10.20 | 1567 | 211304 | 558050 | 62718101 |
Product dose omission in error | 27.17 | 10.20 | 71 | 212800 | 7541 | 63268610 |
Laryngeal stenosis | 26.96 | 10.20 | 25 | 212846 | 1053 | 63275098 |
Mononeuropathy multiplex | 26.92 | 10.20 | 15 | 212856 | 277 | 63275874 |
Hepatic failure | 26.86 | 10.20 | 49 | 212822 | 35607 | 63240544 |
Pharyngeal swelling | 26.29 | 10.20 | 63 | 212808 | 6341 | 63269810 |
Hypercapnia | 26.26 | 10.20 | 57 | 212814 | 5374 | 63270777 |
Pharyngitis streptococcal | 26.09 | 10.20 | 87 | 212784 | 10585 | 63265566 |
Progressive multifocal leukoencephalopathy | 25.61 | 10.20 | 6 | 212865 | 12965 | 63263186 |
Ear discomfort | 25.46 | 10.20 | 71 | 212800 | 7835 | 63268316 |
Injection site pain | 25.42 | 10.20 | 592 | 212279 | 129208 | 63146943 |
Joint stiffness | 25.35 | 10.20 | 65 | 212806 | 41804 | 63234347 |
Lung diffusion test decreased | 25.25 | 10.20 | 20 | 212851 | 678 | 63275473 |
Acute respiratory distress syndrome | 25.18 | 10.20 | 25 | 212846 | 23509 | 63252642 |
Upper airway obstruction | 25.12 | 10.20 | 20 | 212851 | 683 | 63275468 |
Night sweats | 25.01 | 10.20 | 82 | 212789 | 48732 | 63227419 |
Ill-defined disorder | 24.88 | 10.20 | 166 | 212705 | 81589 | 63194562 |
Hepatic function abnormal | 24.60 | 10.20 | 55 | 212816 | 37087 | 63239064 |
Bronchospasm paradoxical | 24.48 | 10.20 | 10 | 212861 | 88 | 63276063 |
Swollen tongue | 24.47 | 10.20 | 200 | 212671 | 34600 | 63241551 |
Mycotic allergy | 24.45 | 10.20 | 23 | 212848 | 987 | 63275164 |
Spinal operation | 24.43 | 10.20 | 72 | 212799 | 8199 | 63267952 |
Blood pressure fluctuation | 24.29 | 10.20 | 77 | 212794 | 46240 | 63229911 |
Influenza like illness | 24.24 | 10.20 | 336 | 212535 | 66488 | 63209663 |
Hiatus hernia | 24.07 | 10.20 | 139 | 212732 | 21455 | 63254696 |
Nocturnal fear | 24.07 | 10.20 | 6 | 212865 | 6 | 63276145 |
Oropharyngeal discomfort | 24.07 | 10.20 | 54 | 212817 | 5206 | 63270945 |
Frequent bowel movements | 24.01 | 10.20 | 25 | 212846 | 22997 | 63253154 |
Cognitive disorder | 23.87 | 10.20 | 101 | 212770 | 55714 | 63220437 |
Conjunctivitis allergic | 23.86 | 10.20 | 22 | 212849 | 920 | 63275231 |
Lung disorder | 23.79 | 10.20 | 316 | 212555 | 61945 | 63214206 |
Incorrect dose administered | 23.60 | 10.20 | 306 | 212565 | 59662 | 63216489 |
Chest pain | 23.30 | 10.20 | 915 | 211956 | 215044 | 63061107 |
Increased upper airway secretion | 23.09 | 10.20 | 43 | 212828 | 3629 | 63272522 |
Foot deformity | 23.08 | 10.20 | 36 | 212835 | 27817 | 63248334 |
Neuroleptic malignant syndrome | 22.98 | 10.20 | 6 | 212865 | 12050 | 63264101 |
Appetite disorder | 22.85 | 10.20 | 65 | 212806 | 7256 | 63268895 |
Thinking abnormal | 22.75 | 10.20 | 83 | 212788 | 10560 | 63265591 |
Drug resistance | 22.71 | 10.20 | 26 | 212845 | 22907 | 63253244 |
Airway remodelling | 22.57 | 10.20 | 9 | 212862 | 74 | 63276077 |
Tenosynovitis | 22.52 | 10.20 | 9 | 212862 | 13786 | 63262365 |
Anosmia | 22.48 | 10.20 | 62 | 212809 | 6798 | 63269353 |
Pregnancy | 22.44 | 10.20 | 57 | 212814 | 36779 | 63239372 |
Overweight | 22.44 | 10.20 | 43 | 212828 | 3708 | 63272443 |
Muscle spasticity | 22.36 | 10.20 | 24 | 212847 | 21770 | 63254381 |
Separation anxiety disorder | 22.35 | 10.20 | 7 | 212864 | 25 | 63276126 |
Metastases to central nervous system | 22.32 | 10.20 | 8 | 212863 | 13097 | 63263054 |
Inappropriate antidiuretic hormone secretion | 22.29 | 10.20 | 12 | 212859 | 15450 | 63260701 |
Ligament pain | 22.26 | 10.20 | 12 | 212859 | 207 | 63275944 |
Sedation | 22.17 | 10.20 | 62 | 212809 | 38747 | 63237404 |
Blood alkaline phosphatase increased | 22.14 | 10.20 | 72 | 212799 | 42895 | 63233256 |
CFTR gene mutation | 22.07 | 10.20 | 10 | 212861 | 116 | 63276035 |
Infusion site urticaria | 22.05 | 10.20 | 27 | 212844 | 1569 | 63274582 |
Drug eruption | 22 | 10.20 | 39 | 212832 | 28655 | 63247496 |
Myalgia | 21.92 | 10.20 | 645 | 212226 | 145884 | 63130267 |
Cerebral infarction | 21.65 | 10.20 | 29 | 212842 | 23864 | 63252287 |
Nasal inflammation | 21.54 | 10.20 | 16 | 212855 | 492 | 63275659 |
Bacteraemia | 21.52 | 10.20 | 16 | 212855 | 17332 | 63258819 |
Skin necrosis | 21.35 | 10.20 | 10 | 212861 | 13940 | 63262211 |
Torsade de pointes | 21.33 | 10.20 | 9 | 212862 | 13342 | 63262809 |
Hypercalcaemia | 21.26 | 10.20 | 39 | 212832 | 28283 | 63247868 |
Depressed mood | 21.16 | 10.20 | 217 | 212654 | 39974 | 63236177 |
Somnambulism | 21.13 | 10.20 | 53 | 212818 | 5490 | 63270661 |
Panniculitis | 21.07 | 10.20 | 6 | 212865 | 11379 | 63264772 |
Lower respiratory tract congestion | 20.98 | 10.20 | 36 | 212835 | 2850 | 63273301 |
Drug reaction with eosinophilia and systemic symptoms | 20.89 | 10.20 | 52 | 212819 | 33784 | 63242367 |
Pre-existing condition improved | 20.86 | 10.20 | 68 | 212803 | 8176 | 63267975 |
Skin lesion | 20.77 | 10.20 | 175 | 212696 | 30546 | 63245605 |
Anaphylactic shock | 20.67 | 10.20 | 143 | 212728 | 23490 | 63252661 |
Expiratory reserve volume decreased | 20.65 | 10.20 | 7 | 212864 | 34 | 63276117 |
Foetal exposure during pregnancy | 20.62 | 10.20 | 48 | 212823 | 31914 | 63244237 |
Hepatotoxicity | 20.55 | 10.20 | 60 | 212811 | 36981 | 63239170 |
Colitis ulcerative | 20.42 | 10.20 | 35 | 212836 | 26056 | 63250095 |
Choking sensation | 20.36 | 10.20 | 40 | 212831 | 3514 | 63272637 |
Rhinitis perennial | 20.32 | 10.20 | 7 | 212864 | 36 | 63276115 |
Serotonin syndrome | 20.22 | 10.20 | 41 | 212830 | 28641 | 63247510 |
Major depression | 20.17 | 10.20 | 66 | 212805 | 7952 | 63268199 |
Acute hepatic failure | 20.15 | 10.20 | 19 | 212852 | 18308 | 63257843 |
Oesophageal dilatation | 20.15 | 10.20 | 14 | 212857 | 387 | 63275764 |
Obstruction | 20.14 | 10.20 | 37 | 212834 | 3090 | 63273061 |
Exposure to allergen | 20.14 | 10.20 | 13 | 212858 | 317 | 63275834 |
Paranasal sinus discomfort | 20.11 | 10.20 | 45 | 212826 | 4331 | 63271820 |
Musculoskeletal pain | 20.04 | 10.20 | 205 | 212666 | 92072 | 63184079 |
Educational problem | 19.99 | 10.20 | 14 | 212857 | 392 | 63275759 |
Hyperhidrosis | 19.94 | 10.20 | 488 | 212383 | 107348 | 63168803 |
Dyspnoea at rest | 19.94 | 10.20 | 43 | 212828 | 4036 | 63272115 |
Pneumonia aspiration | 19.86 | 10.20 | 55 | 212816 | 34485 | 63241666 |
Hospitalisation | 19.84 | 10.20 | 398 | 212473 | 84683 | 63191468 |
Muscle tension dysphonia | 19.75 | 10.20 | 11 | 212860 | 203 | 63275948 |
Epilepsy | 19.67 | 10.20 | 38 | 212833 | 27027 | 63249124 |
Atrial fibrillation | 19.62 | 10.20 | 274 | 212597 | 116362 | 63159789 |
Ligament sprain | 19.57 | 10.20 | 90 | 212781 | 12710 | 63263441 |
Product container issue | 19.57 | 10.20 | 27 | 212844 | 1766 | 63274385 |
Ulcer | 19.55 | 10.20 | 36 | 212835 | 26071 | 63250080 |
Nephropathy toxic | 19.49 | 10.20 | 4 | 212867 | 9475 | 63266676 |
Pleural effusion | 19.46 | 10.20 | 209 | 212662 | 93001 | 63183150 |
Exposure during pregnancy | 19.42 | 10.20 | 386 | 212485 | 155161 | 63120990 |
Eosinophilic oesophagitis | 19.40 | 10.20 | 13 | 212858 | 338 | 63275813 |
Eosinophilic pneumonia acute | 19.38 | 10.20 | 14 | 212857 | 412 | 63275739 |
Cytokine release syndrome | 19.36 | 10.20 | 12 | 212859 | 14302 | 63261849 |
Ischaemic stroke | 19.30 | 10.20 | 19 | 212852 | 17938 | 63258213 |
Injection site movement impairment | 19.25 | 10.20 | 6 | 212865 | 21 | 63276130 |
Product substitution issue | 19.18 | 10.20 | 105 | 212766 | 15891 | 63260260 |
Self-injurious ideation | 19.11 | 10.20 | 33 | 212838 | 2626 | 63273525 |
Electrocardiogram QT prolonged | 19.07 | 10.20 | 119 | 212752 | 59411 | 63216740 |
Body temperature decreased | 19.00 | 10.20 | 125 | 212746 | 20194 | 63255957 |
Blood immunoglobulin E decreased | 18.96 | 10.20 | 8 | 212863 | 77 | 63276074 |
Airway peak pressure increased | 18.94 | 10.20 | 12 | 212859 | 283 | 63275868 |
Liver function test abnormal | 18.91 | 10.20 | 90 | 212781 | 48091 | 63228060 |
Candida infection | 18.90 | 10.20 | 161 | 212710 | 28190 | 63247961 |
Tuberculosis | 18.83 | 10.20 | 7 | 212864 | 11204 | 63264947 |
Allergy test positive | 18.73 | 10.20 | 16 | 212855 | 604 | 63275547 |
Adrenal suppression | 18.56 | 10.20 | 19 | 212852 | 905 | 63275246 |
Upper limb fracture | 18.54 | 10.20 | 118 | 212753 | 18850 | 63257301 |
Ear swelling | 18.52 | 10.20 | 24 | 212847 | 1477 | 63274674 |
Sinus polyp degeneration | 18.52 | 10.20 | 7 | 212864 | 49 | 63276102 |
Accidental overdose | 18.49 | 10.20 | 31 | 212840 | 23278 | 63252873 |
Sinus operation | 18.46 | 10.20 | 32 | 212839 | 2554 | 63273597 |
Cold urticaria | 18.30 | 10.20 | 9 | 212862 | 127 | 63276024 |
Cytopenia | 18.25 | 10.20 | 8 | 212863 | 11593 | 63264558 |
Eye swelling | 18.21 | 10.20 | 140 | 212731 | 23778 | 63252373 |
Fungal infection | 17.96 | 10.20 | 196 | 212675 | 36678 | 63239473 |
Functional residual capacity increased | 17.95 | 10.20 | 8 | 212863 | 89 | 63276062 |
Hypoglycaemia | 17.76 | 10.20 | 123 | 212748 | 59942 | 63216209 |
Emotional distress | 17.74 | 10.20 | 177 | 212694 | 32372 | 63243779 |
Lactose intolerance | 17.65 | 10.20 | 34 | 212837 | 2944 | 63273207 |
Vasculitis | 17.63 | 10.20 | 113 | 212758 | 18096 | 63258055 |
Speech disorder | 17.56 | 10.20 | 211 | 212660 | 40418 | 63235733 |
Bronchial hyperreactivity | 17.49 | 10.20 | 25 | 212846 | 1690 | 63274461 |
Peritonitis | 17.47 | 10.20 | 19 | 212852 | 17135 | 63259016 |
Weight decreased | 17.39 | 10.20 | 1113 | 211758 | 275685 | 63000466 |
Diverticulum | 17.37 | 10.20 | 83 | 212788 | 11908 | 63264243 |
Hypoalbuminaemia | 17.25 | 10.20 | 9 | 212862 | 11796 | 63264355 |
Sputum culture | 17.23 | 10.20 | 11 | 212860 | 263 | 63275888 |
Paranoia | 17.04 | 10.20 | 81 | 212790 | 11598 | 63264553 |
Altered state of consciousness | 17.00 | 10.20 | 37 | 212834 | 25193 | 63250958 |
Premature baby | 16.99 | 10.20 | 27 | 212844 | 20708 | 63255443 |
Injection site scab | 16.92 | 10.20 | 13 | 212858 | 421 | 63275730 |
Eye paraesthesia | 16.92 | 10.20 | 9 | 212862 | 151 | 63276000 |
Insurance issue | 16.87 | 10.20 | 52 | 212819 | 6069 | 63270082 |
Lymphopenia | 16.86 | 10.20 | 22 | 212849 | 18305 | 63257846 |
Blood calcium decreased | 16.84 | 10.20 | 40 | 212831 | 26411 | 63249740 |
Metastases to lung | 16.82 | 10.20 | 11 | 212860 | 12739 | 63263412 |
Acute sinusitis | 16.78 | 10.20 | 39 | 212832 | 3848 | 63272303 |
Vocal cord disorder | 16.77 | 10.20 | 22 | 212849 | 1371 | 63274780 |
Gluten sensitivity | 16.72 | 10.20 | 15 | 212856 | 605 | 63275546 |
Subarachnoid haemorrhage | 16.67 | 10.20 | 14 | 212857 | 14269 | 63261882 |
Haematochezia | 16.65 | 10.20 | 108 | 212763 | 53436 | 63222715 |
Blood parathyroid hormone decreased | 16.63 | 10.20 | 6 | 212865 | 9785 | 63266366 |
Forced expiratory volume | 16.63 | 10.20 | 5 | 212866 | 15 | 63276136 |
Diabetic ketoacidosis | 16.52 | 10.20 | 27 | 212844 | 20478 | 63255673 |
Immunisation reaction | 16.52 | 10.20 | 15 | 212856 | 615 | 63275536 |
Respiratory tract irritation | 16.48 | 10.20 | 13 | 212858 | 438 | 63275713 |
Stevens-Johnson syndrome | 16.48 | 10.20 | 37 | 212834 | 24913 | 63251238 |
Grip strength decreased | 16.46 | 10.20 | 31 | 212840 | 22256 | 63253895 |
Pneumococcal infection | 16.38 | 10.20 | 13 | 212858 | 442 | 63275709 |
Breast cancer metastatic | 16.36 | 10.20 | 10 | 212861 | 12008 | 63264143 |
Onychophagia | 16.36 | 10.20 | 7 | 212864 | 70 | 63276081 |
Melaena | 16.26 | 10.20 | 50 | 212821 | 30315 | 63245836 |
Pulmonary thrombosis | 16.25 | 10.20 | 65 | 212806 | 8637 | 63267514 |
Bronchial irritation | 16.16 | 10.20 | 5 | 212866 | 17 | 63276134 |
Palpitations | 15.95 | 10.20 | 493 | 212378 | 112277 | 63163874 |
Nodular vasculitis | 15.94 | 10.20 | 5 | 212866 | 18 | 63276133 |
Oxygen consumption decreased | 15.93 | 10.20 | 10 | 212861 | 232 | 63275919 |
Snoring | 15.83 | 10.20 | 40 | 212831 | 4162 | 63271989 |
Posterior reversible encephalopathy syndrome | 15.77 | 10.20 | 21 | 212850 | 17324 | 63258827 |
Sinus headache | 15.75 | 10.20 | 48 | 212823 | 5568 | 63270583 |
Pulmonary toxicity | 15.72 | 10.20 | 6 | 212865 | 9449 | 63266702 |
Attention deficit hyperactivity disorder | 15.70 | 10.20 | 33 | 212838 | 3043 | 63273108 |
Mouth swelling | 15.69 | 10.20 | 43 | 212828 | 4697 | 63271454 |
Haemophagocytic lymphohistiocytosis | 15.68 | 10.20 | 8 | 212863 | 10619 | 63265532 |
Forced expiratory volume abnormal | 15.62 | 10.20 | 7 | 212864 | 79 | 63276072 |
Allergic sinusitis | 15.53 | 10.20 | 19 | 212852 | 1103 | 63275048 |
Cortisol decreased | 15.52 | 10.20 | 20 | 212851 | 1224 | 63274927 |
Sinus polyp | 15.51 | 10.20 | 12 | 212859 | 393 | 63275758 |
Acute generalised exanthematous pustulosis | 15.44 | 10.20 | 9 | 212862 | 11090 | 63265061 |
Depressive symptom | 15.40 | 10.20 | 39 | 212832 | 4063 | 63272088 |
Product availability issue | 15.29 | 10.20 | 39 | 212832 | 4082 | 63272069 |
Drug-induced liver injury | 15.28 | 10.20 | 76 | 212795 | 40146 | 63236005 |
Neurogenic shock | 15.25 | 10.20 | 11 | 212860 | 323 | 63275828 |
Nervousness | 15.24 | 10.20 | 165 | 212706 | 30814 | 63245337 |
Unresponsive to stimuli | 15.20 | 10.20 | 60 | 212811 | 33756 | 63242395 |
Diastolic dysfunction | 15.15 | 10.20 | 52 | 212819 | 6419 | 63269732 |
Acute myocardial infarction | 15.09 | 10.20 | 56 | 212815 | 32068 | 63244083 |
Device expulsion | 15.05 | 10.20 | 63 | 212808 | 34859 | 63241292 |
Hypothermia | 15.03 | 10.20 | 14 | 212857 | 13567 | 63262584 |
SARS-CoV-2 test positive | 14.90 | 10.20 | 60 | 212811 | 7996 | 63268155 |
Forced expiratory flow decreased | 14.88 | 10.20 | 7 | 212864 | 89 | 63276062 |
Miller Fisher syndrome | 14.88 | 10.20 | 7 | 212864 | 89 | 63276062 |
Intentional dose omission | 14.82 | 10.20 | 60 | 212811 | 8015 | 63268136 |
Lip dry | 14.82 | 10.20 | 18 | 212853 | 15452 | 63260699 |
Coagulopathy | 14.80 | 10.20 | 29 | 212842 | 20515 | 63255636 |
Laryngitis fungal | 14.79 | 10.20 | 8 | 212863 | 139 | 63276012 |
Otorrhoea | 14.71 | 10.20 | 21 | 212850 | 1418 | 63274733 |
Proteinuria | 14.70 | 10.20 | 26 | 212845 | 19119 | 63257032 |
Blood lactate dehydrogenase increased | 14.69 | 10.20 | 35 | 212836 | 23081 | 63253070 |
Low birth weight baby | 14.68 | 10.20 | 3 | 212868 | 7126 | 63269025 |
Oral pruritus | 14.62 | 10.20 | 27 | 212844 | 2264 | 63273887 |
Osteomyelitis | 14.54 | 10.20 | 42 | 212829 | 25978 | 63250173 |
Hepatic encephalopathy | 14.53 | 10.20 | 10 | 212861 | 11272 | 63264879 |
Medication error | 14.52 | 10.20 | 109 | 212762 | 52175 | 63223976 |
Nausea | 14.44 | 10.20 | 2584 | 210287 | 851887 | 62424264 |
Temperature intolerance | 14.43 | 10.20 | 64 | 212807 | 8900 | 63267251 |
Sedation complication | 14.43 | 10.20 | 15 | 212856 | 13807 | 63262344 |
Jaundice | 14.40 | 10.20 | 50 | 212821 | 29201 | 63246950 |
Basal cell carcinoma | 14.35 | 10.20 | 47 | 212824 | 27944 | 63248207 |
Hallucination | 14.34 | 10.20 | 261 | 212610 | 54556 | 63221595 |
Body temperature abnormal | 14.23 | 10.20 | 25 | 212846 | 2016 | 63274135 |
Pulmonary function challenge test abnormal | 14.10 | 10.20 | 3 | 212868 | 0 | 63276151 |
Sleep study abnormal | 14.10 | 10.20 | 3 | 212868 | 0 | 63276151 |
Glomus tumour | 14.10 | 10.20 | 3 | 212868 | 0 | 63276151 |
Cardiogenic shock | 14.09 | 10.20 | 24 | 212847 | 17908 | 63258243 |
Administration site erythema | 14.06 | 10.20 | 15 | 212856 | 750 | 63275401 |
PCO2 increased | 14.04 | 10.20 | 19 | 212852 | 1220 | 63274931 |
Product taste abnormal | 14.01 | 10.20 | 25 | 212846 | 2042 | 63274109 |
Clostridium difficile colitis | 14.00 | 10.20 | 30 | 212841 | 20539 | 63255612 |
Infusion site mass | 14.00 | 10.20 | 25 | 212846 | 2043 | 63274108 |
Product contamination physical | 13.91 | 10.20 | 7 | 212864 | 104 | 63276047 |
Pneumocystis jirovecii pneumonia | 13.88 | 10.20 | 22 | 212849 | 16892 | 63259259 |
Macular degeneration | 13.88 | 10.20 | 39 | 212832 | 24337 | 63251814 |
Sinus bradycardia | 13.87 | 10.20 | 17 | 212854 | 14534 | 63261617 |
Respiratory tract infection viral | 13.82 | 10.20 | 26 | 212845 | 2211 | 63273940 |
Uveitis | 13.82 | 10.20 | 13 | 212858 | 12540 | 63263611 |
International normalised ratio increased | 13.76 | 10.20 | 95 | 212776 | 46330 | 63229821 |
Blood calcium increased | 13.75 | 10.20 | 65 | 212806 | 9285 | 63266866 |
Alice in wonderland syndrome | 13.74 | 10.20 | 5 | 212866 | 31 | 63276120 |
Bipolar disorder | 13.71 | 10.20 | 58 | 212813 | 7902 | 63268249 |
Left ventricular dysfunction | 13.69 | 10.20 | 12 | 212859 | 11976 | 63264175 |
Squamous cell carcinoma of the oral cavity | 13.62 | 10.20 | 10 | 212861 | 302 | 63275849 |
Myelodysplastic syndrome | 13.55 | 10.20 | 22 | 212849 | 16732 | 63259419 |
Sciatica | 13.54 | 10.20 | 64 | 212807 | 34260 | 63241891 |
Lip discolouration | 13.42 | 10.20 | 13 | 212858 | 579 | 63275572 |
Product packaging confusion | 13.40 | 10.20 | 8 | 212863 | 169 | 63275982 |
Respiratory arrest | 13.39 | 10.20 | 60 | 212811 | 32585 | 63243566 |
Miosis | 13.38 | 10.20 | 4 | 212867 | 7349 | 63268802 |
Infusion site rash | 13.36 | 10.20 | 24 | 212847 | 1970 | 63274181 |
Injection site hypoaesthesia | 13.36 | 10.20 | 12 | 212859 | 485 | 63275666 |
Pneumonia respiratory syncytial viral | 13.29 | 10.20 | 17 | 212854 | 1033 | 63275118 |
Lung diffusion disorder | 13.29 | 10.20 | 6 | 212865 | 69 | 63276082 |
Vaccination complication | 13.26 | 10.20 | 18 | 212853 | 1159 | 63274992 |
Upper gastrointestinal haemorrhage | 13.25 | 10.20 | 27 | 212844 | 18825 | 63257326 |
Sputum retention | 13.23 | 10.20 | 13 | 212858 | 589 | 63275562 |
Mandibular mass | 13.20 | 10.20 | 8 | 212863 | 174 | 63275977 |
Atrioventricular block first degree | 13.16 | 10.20 | 4 | 212867 | 7269 | 63268882 |
Mucosal discolouration | 13.13 | 10.20 | 12 | 212859 | 496 | 63275655 |
Distal intestinal obstruction syndrome | 13.07 | 10.20 | 11 | 212860 | 407 | 63275744 |
Hepatic cirrhosis | 13.05 | 10.20 | 41 | 212830 | 24693 | 63251458 |
Blood urea increased | 13.04 | 10.20 | 45 | 212826 | 26334 | 63249817 |
Female sterilisation | 13.00 | 10.20 | 13 | 212858 | 602 | 63275549 |
Aplastic anaemia | 12.97 | 10.20 | 8 | 212863 | 9561 | 63266590 |
Stress urinary incontinence | 12.88 | 10.20 | 26 | 212845 | 2329 | 63273822 |
Female reproductive neoplasm | 12.88 | 10.20 | 5 | 212866 | 38 | 63276113 |
Cold agglutinins positive | 12.88 | 10.20 | 5 | 212866 | 38 | 63276113 |
Weight increased | 12.82 | 10.20 | 1028 | 211843 | 259764 | 63016387 |
Injection site urticaria | 12.81 | 10.20 | 86 | 212785 | 13987 | 63262164 |
Incorrect route of product administration | 12.80 | 10.20 | 48 | 212823 | 27404 | 63248747 |
Neoplasm malignant | 12.79 | 10.20 | 54 | 212817 | 29807 | 63246344 |
Body mass index increased | 12.76 | 10.20 | 18 | 212853 | 1202 | 63274949 |
Therapeutic response unexpected | 12.75 | 10.20 | 107 | 212764 | 18652 | 63257499 |
Disease recurrence | 12.75 | 10.20 | 147 | 212724 | 27883 | 63248268 |
Nocturnal dyspnoea | 12.72 | 10.20 | 18 | 212853 | 1206 | 63274945 |
Decubitus ulcer | 12.67 | 10.20 | 10 | 212861 | 10510 | 63265641 |
Product appearance confusion | 12.65 | 10.20 | 5 | 212866 | 40 | 63276111 |
Vaccination site swelling | 12.65 | 10.20 | 5 | 212866 | 40 | 63276111 |
Eczema impetiginous | 12.62 | 10.20 | 4 | 212867 | 15 | 63276136 |
Functional residual capacity decreased | 12.57 | 10.20 | 6 | 212865 | 79 | 63276072 |
Neuropsychiatric syndrome | 12.55 | 10.20 | 5 | 212866 | 41 | 63276110 |
Cholelithiasis | 12.51 | 10.20 | 212 | 212659 | 43713 | 63232438 |
Hyperventilation | 12.49 | 10.20 | 47 | 212824 | 6069 | 63270082 |
Back pain | 12.47 | 10.20 | 1038 | 211833 | 263107 | 63013044 |
Malnutrition | 12.46 | 10.20 | 20 | 212851 | 15278 | 63260873 |
Hyperlipidaemia | 12.45 | 10.20 | 110 | 212761 | 19461 | 63256690 |
Inhalation therapy | 12.44 | 10.20 | 5 | 212866 | 42 | 63276109 |
Hypertensive crisis | 12.43 | 10.20 | 20 | 212851 | 15266 | 63260885 |
Pulmonary eosinophilia | 12.43 | 10.20 | 10 | 212861 | 347 | 63275804 |
Rectal haemorrhage | 12.33 | 10.20 | 105 | 212766 | 48925 | 63227226 |
Glossitis | 12.31 | 10.20 | 30 | 212841 | 3052 | 63273099 |
Nasal septum deviation | 12.29 | 10.20 | 20 | 212851 | 1516 | 63274635 |
Renal tubular necrosis | 12.27 | 10.20 | 13 | 212858 | 11865 | 63264286 |
Device delivery system issue | 12.27 | 10.20 | 14 | 212857 | 755 | 63275396 |
Abnormal weight gain | 12.23 | 10.20 | 22 | 212849 | 1808 | 63274343 |
Injection site pruritus | 12.22 | 10.20 | 216 | 212655 | 44900 | 63231251 |
Skin sensitisation | 12.22 | 10.20 | 15 | 212856 | 874 | 63275277 |
Neuropathy peripheral | 12.18 | 10.20 | 289 | 212582 | 113378 | 63162773 |
Painful respiration | 12.16 | 10.20 | 28 | 212843 | 2746 | 63273405 |
Femur fracture | 12.10 | 10.20 | 86 | 212785 | 41670 | 63234481 |
Breast cancer stage I | 12.09 | 10.20 | 4 | 212867 | 6885 | 63269266 |
Dyslipidaemia | 12.07 | 10.20 | 53 | 212818 | 7340 | 63268811 |
Oropharyngitis fungal | 12.05 | 10.20 | 5 | 212866 | 46 | 63276105 |
Muscular weakness | 12.05 | 10.20 | 315 | 212556 | 122038 | 63154113 |
Defiant behaviour | 12.04 | 10.20 | 3 | 212868 | 3 | 63276148 |
Platelet adhesiveness decreased | 12.04 | 10.20 | 3 | 212868 | 3 | 63276148 |
Accident | 12.03 | 10.20 | 46 | 212825 | 5986 | 63270165 |
Asthenia | 12.00 | 10.20 | 1115 | 211756 | 382489 | 62893662 |
Tubulointerstitial nephritis | 11.97 | 10.20 | 31 | 212840 | 19872 | 63256279 |
Cephalo-pelvic disproportion | 11.94 | 10.20 | 8 | 212863 | 208 | 63275943 |
Flushing | 11.91 | 10.20 | 333 | 212538 | 74754 | 63201397 |
Poisoning deliberate | 11.91 | 10.20 | 12 | 212859 | 11206 | 63264945 |
Diverticulum oesophageal | 11.89 | 10.20 | 7 | 212864 | 144 | 63276007 |
Sensation of foreign body | 11.88 | 10.20 | 39 | 212832 | 4706 | 63271445 |
Middle ear effusion | 11.88 | 10.20 | 26 | 212845 | 2465 | 63273686 |
Quarantine | 11.86 | 10.20 | 5 | 212866 | 48 | 63276103 |
Klebsiella infection | 11.84 | 10.20 | 7 | 212864 | 8559 | 63267592 |
Hypereosinophilic syndrome | 11.84 | 10.20 | 9 | 212862 | 287 | 63275864 |
Mechanical urticaria | 11.83 | 10.20 | 11 | 212860 | 465 | 63275686 |
Pulmonary embolism | 11.78 | 10.20 | 491 | 212380 | 116193 | 63159958 |
Proctalgia | 11.72 | 10.20 | 3 | 212868 | 6107 | 63270044 |
Dermatitis bullous | 11.69 | 10.20 | 7 | 212864 | 8501 | 63267650 |
Obsessive-compulsive disorder | 11.67 | 10.20 | 35 | 212836 | 4025 | 63272126 |
Vasomotor rhinitis | 11.64 | 10.20 | 7 | 212864 | 150 | 63276001 |
Prothrombin time prolonged | 11.63 | 10.20 | 9 | 212862 | 9555 | 63266596 |
Drug level decreased | 11.63 | 10.20 | 6 | 212865 | 7913 | 63268238 |
Obsessive thoughts | 11.59 | 10.20 | 12 | 212859 | 579 | 63275572 |
Injection site erythema | 11.59 | 10.20 | 363 | 212508 | 82811 | 63193340 |
School refusal | 11.58 | 10.20 | 3 | 212868 | 4 | 63276147 |
Gastroenteritis viral | 11.55 | 10.20 | 126 | 212745 | 23574 | 63252577 |
Gallbladder disorder | 11.53 | 10.20 | 105 | 212766 | 18737 | 63257414 |
Agoraphobia | 11.52 | 10.20 | 10 | 212861 | 386 | 63275765 |
Status epilepticus | 11.41 | 10.20 | 21 | 212850 | 15212 | 63260939 |
Exposure to fungus | 11.40 | 10.20 | 7 | 212864 | 156 | 63275995 |
Infusion site nodule | 11.36 | 10.20 | 19 | 212852 | 1473 | 63274678 |
Gait inability | 11.35 | 10.20 | 118 | 212753 | 52841 | 63223310 |
Phlebectomy | 11.35 | 10.20 | 5 | 212866 | 54 | 63276097 |
Hypertransaminasaemia | 11.31 | 10.20 | 4 | 212867 | 6605 | 63269546 |
Abdominal pain lower | 11.27 | 10.20 | 46 | 212825 | 25632 | 63250519 |
Angiodysplasia | 11.24 | 10.20 | 10 | 212861 | 399 | 63275752 |
PO2 decreased | 11.23 | 10.20 | 19 | 212852 | 1487 | 63274664 |
Mycobacterium avium complex infection | 11.22 | 10.20 | 29 | 212842 | 3059 | 63273092 |
Screaming | 11.21 | 10.20 | 30 | 212841 | 3232 | 63272919 |
Enterobiasis | 11.19 | 10.20 | 5 | 212866 | 56 | 63276095 |
Finger deformity | 11.18 | 10.20 | 6 | 212865 | 7739 | 63268412 |
Cerebral haemorrhage | 11.14 | 10.20 | 59 | 212812 | 30670 | 63245481 |
Oesophagogastroduodenoscopy | 11.09 | 10.20 | 7 | 212864 | 164 | 63275987 |
Skin swelling | 11.08 | 10.20 | 31 | 212840 | 3428 | 63272723 |
Poisoning | 11.07 | 10.20 | 18 | 212853 | 13682 | 63262469 |
Infusion site warmth | 11.07 | 10.20 | 21 | 212850 | 1797 | 63274354 |
Hyperbilirubinaemia | 11.01 | 10.20 | 13 | 212858 | 11301 | 63264850 |
Vaccination site pain | 11.01 | 10.20 | 7 | 212864 | 166 | 63275985 |
Administration site pruritus | 11.00 | 10.20 | 9 | 212862 | 320 | 63275831 |
Blood immunoglobulin G decreased | 10.99 | 10.20 | 25 | 212846 | 2433 | 63273718 |
Mental disorder | 10.94 | 10.20 | 134 | 212737 | 25785 | 63250366 |
Myoclonus | 10.92 | 10.20 | 23 | 212848 | 15845 | 63260306 |
Laryngeal oedema | 10.91 | 10.20 | 43 | 212828 | 5675 | 63270476 |
Hearing aid user | 10.88 | 10.20 | 5 | 212866 | 60 | 63276091 |
Pulmonary arterial hypertension | 10.84 | 10.20 | 39 | 212832 | 22538 | 63253613 |
Peak expiratory flow rate increased | 10.83 | 10.20 | 3 | 212868 | 6 | 63276145 |
Deformity | 10.77 | 10.20 | 14 | 212857 | 11670 | 63264481 |
Fear | 10.76 | 10.20 | 90 | 212781 | 15676 | 63260475 |
Endocarditis | 10.70 | 10.20 | 3 | 212868 | 5747 | 63270404 |
Hypovolaemia | 10.68 | 10.20 | 12 | 212859 | 10661 | 63265490 |
Lupus-like syndrome | 10.67 | 10.20 | 22 | 212849 | 15273 | 63260878 |
Therapy partial responder | 10.64 | 10.20 | 12 | 212859 | 10646 | 63265505 |
Intentional product misuse | 10.64 | 10.20 | 142 | 212729 | 60775 | 63215376 |
Chronic kidney disease | 10.63 | 10.20 | 99 | 212772 | 45299 | 63230852 |
Paraesthesia oral | 10.63 | 10.20 | 105 | 212766 | 19151 | 63257000 |
Anaphylactoid reaction | 10.61 | 10.20 | 32 | 212839 | 3691 | 63272460 |
Breast neoplasm | 10.59 | 10.20 | 18 | 212853 | 1414 | 63274737 |
Gastroenteritis eosinophilic | 10.57 | 10.20 | 6 | 212865 | 115 | 63276036 |
Alcohol intolerance | 10.57 | 10.20 | 6 | 212865 | 115 | 63276036 |
Glomerular filtration rate decreased | 10.55 | 10.20 | 18 | 212853 | 13423 | 63262728 |
Serum sickness | 10.54 | 10.20 | 27 | 212844 | 2833 | 63273318 |
Urinary retention | 10.54 | 10.20 | 59 | 212812 | 30242 | 63245909 |
Mouth ulceration | 10.53 | 10.20 | 66 | 212805 | 32918 | 63243233 |
Oliguria | 10.53 | 10.20 | 9 | 212862 | 9092 | 63267059 |
Postpartum anxiety | 10.52 | 10.20 | 3 | 212868 | 7 | 63276144 |
Haemorrhage intracranial | 10.50 | 10.20 | 18 | 212853 | 13401 | 63262750 |
Congenital naevus | 10.48 | 10.20 | 7 | 212864 | 181 | 63275970 |
Granulocytopenia | 10.48 | 10.20 | 3 | 212868 | 5669 | 63270482 |
Surgery | 10.48 | 10.20 | 174 | 212697 | 35738 | 63240413 |
Eyelid infection | 10.46 | 10.20 | 9 | 212862 | 343 | 63275808 |
Administration site swelling | 10.43 | 10.20 | 17 | 212854 | 1290 | 63274861 |
Anticholinergic syndrome | 10.39 | 10.20 | 24 | 212847 | 2358 | 63273793 |
Femoral neck fracture | 10.39 | 10.20 | 8 | 212863 | 8515 | 63267636 |
Microscopic polyangiitis | 10.38 | 10.20 | 7 | 212864 | 184 | 63275967 |
Muscle rigidity | 10.38 | 10.20 | 14 | 212857 | 11486 | 63264665 |
Intestinal perforation | 10.36 | 10.20 | 15 | 212856 | 11948 | 63264203 |
Pulmonary renal syndrome | 10.35 | 10.20 | 10 | 212861 | 444 | 63275707 |
Breast conserving surgery | 10.27 | 10.20 | 15 | 212856 | 1034 | 63275117 |
Restless legs syndrome | 10.21 | 10.20 | 101 | 212770 | 18430 | 63257721 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Asthma | 3319.83 | 11.09 | 1743 | 81984 | 40913 | 34832291 |
Wheezing | 1452.29 | 11.09 | 1016 | 82711 | 40386 | 34832818 |
Eosinophilic granulomatosis with polyangiitis | 898.87 | 11.09 | 288 | 83439 | 1699 | 34871505 |
Obstructive airways disorder | 825.74 | 11.09 | 495 | 83232 | 14999 | 34858205 |
Cough | 556.12 | 11.09 | 1155 | 82572 | 148985 | 34724219 |
Full blood count abnormal | 530.75 | 11.09 | 404 | 83323 | 18264 | 34854940 |
Forced expiratory volume decreased | 450.28 | 11.09 | 197 | 83530 | 3006 | 34870198 |
Productive cough | 416.99 | 11.09 | 483 | 83244 | 37330 | 34835874 |
Dyspnoea | 399.09 | 11.09 | 1868 | 81859 | 374914 | 34498290 |
Abnormal behaviour | 355.58 | 11.09 | 365 | 83362 | 24604 | 34848600 |
Suicidal ideation | 346.99 | 11.09 | 455 | 83272 | 39933 | 34833271 |
Sleep disorder due to a general medical condition | 334.23 | 11.09 | 188 | 83539 | 5033 | 34868171 |
Therapeutic product effect incomplete | 322.60 | 11.09 | 494 | 83233 | 50047 | 34823157 |
Toxicity to various agents | 309.02 | 11.09 | 54 | 83673 | 200308 | 34672896 |
Chest discomfort | 290.59 | 11.09 | 491 | 83236 | 54039 | 34819165 |
Aggression | 289.27 | 11.09 | 409 | 83318 | 38555 | 34834649 |
Nightmare | 288.07 | 11.09 | 254 | 83473 | 14137 | 34859067 |
Sleep terror | 282.43 | 11.09 | 129 | 83598 | 2189 | 34871015 |
Nasal congestion | 271.81 | 11.09 | 305 | 83422 | 22752 | 34850452 |
Sinusitis | 260.38 | 11.09 | 402 | 83325 | 41000 | 34832204 |
Blood immunoglobulin E increased | 258.73 | 11.09 | 125 | 83602 | 2421 | 34870783 |
Sputum discoloured | 253.18 | 11.09 | 183 | 83544 | 7629 | 34865575 |
Middle insomnia | 249.81 | 11.09 | 172 | 83555 | 6630 | 34866574 |
Anger | 234.35 | 11.09 | 208 | 83519 | 11676 | 34861528 |
Nasal polyps | 213.20 | 11.09 | 109 | 83618 | 2394 | 34870810 |
Acute kidney injury | 212.74 | 11.09 | 251 | 83476 | 304737 | 34568467 |
Loss of personal independence in daily activities | 211.17 | 11.09 | 324 | 83403 | 32855 | 34840349 |
Anaemia | 194.74 | 11.09 | 164 | 83563 | 233171 | 34640033 |
Impaired quality of life | 183.32 | 11.09 | 134 | 83593 | 5684 | 34867520 |
Anxiety | 178.72 | 11.09 | 584 | 83143 | 98844 | 34774360 |
Depression | 157.45 | 11.09 | 551 | 83176 | 96547 | 34776657 |
Bronchial wall thickening | 150.69 | 11.09 | 71 | 83656 | 1297 | 34871907 |
Pulmonary function test abnormal | 143.13 | 11.09 | 85 | 83642 | 2525 | 34870679 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 142.40 | 11.09 | 67 | 83660 | 1220 | 34871984 |
Mood altered | 140.47 | 11.09 | 138 | 83589 | 8814 | 34864390 |
Pulmonary function test decreased | 139.83 | 11.09 | 107 | 83620 | 4868 | 34868336 |
Bronchiectasis | 135.35 | 11.09 | 141 | 83586 | 9660 | 34863544 |
Gastrooesophageal reflux disease | 134.24 | 11.09 | 287 | 83440 | 37637 | 34835567 |
Drug interaction | 133.04 | 11.09 | 210 | 83517 | 225736 | 34647468 |
Dermatitis atopic | 133.01 | 11.09 | 107 | 83620 | 5240 | 34867964 |
Death | 132.57 | 11.09 | 499 | 83228 | 397550 | 34475654 |
Sleep disorder | 127.70 | 11.09 | 253 | 83474 | 31435 | 34841769 |
Thrombocytopenia | 127.53 | 11.09 | 112 | 83615 | 156135 | 34717069 |
Bronchial secretion retention | 125.37 | 11.09 | 65 | 83662 | 1471 | 34871733 |
Urticaria | 124.46 | 11.09 | 380 | 83347 | 61997 | 34811207 |
Chronic obstructive pulmonary disease | 124.00 | 11.09 | 325 | 83402 | 48593 | 34824611 |
Febrile neutropenia | 121.79 | 11.09 | 90 | 83637 | 136759 | 34736445 |
Rhinorrhoea | 120.84 | 11.09 | 219 | 83508 | 25449 | 34847755 |
Crying | 120.35 | 11.09 | 105 | 83622 | 5757 | 34867447 |
Eosinophilia | 120 | 11.09 | 221 | 83506 | 26001 | 34847203 |
Off label use | 118.62 | 11.09 | 560 | 83167 | 418964 | 34454240 |
Infective pulmonary exacerbation of cystic fibrosis | 118.35 | 11.09 | 111 | 83616 | 6690 | 34866514 |
Seasonal allergy | 116.27 | 11.09 | 109 | 83618 | 6566 | 34866638 |
Bronchial hyperreactivity | 116.09 | 11.09 | 64 | 83663 | 1645 | 34871559 |
Nasopharyngitis | 112.43 | 11.09 | 396 | 83331 | 69572 | 34803632 |
Neuropsychiatric symptoms | 109.26 | 11.09 | 50 | 83677 | 852 | 34872352 |
Right atrial hypertrophy | 108.25 | 11.09 | 48 | 83679 | 757 | 34872447 |
Eosinophil count increased | 105.46 | 11.09 | 116 | 83611 | 8456 | 34864748 |
Bronchitis | 103.50 | 11.09 | 276 | 83451 | 41687 | 34831517 |
Hypotension | 100.06 | 11.09 | 241 | 83486 | 221408 | 34651796 |
Tic | 99.93 | 11.09 | 62 | 83665 | 1996 | 34871208 |
Obstruction | 98.05 | 11.09 | 68 | 83659 | 2651 | 34870553 |
Rhinitis | 96.28 | 11.09 | 96 | 83631 | 6242 | 34866962 |
Pancytopenia | 93.49 | 11.09 | 56 | 83671 | 95101 | 34778103 |
Bronchospasm | 92.21 | 11.09 | 121 | 83606 | 10610 | 34862594 |
Irritability | 92.17 | 11.09 | 191 | 83536 | 24499 | 34848705 |
Asthmatic crisis | 90.85 | 11.09 | 37 | 83690 | 467 | 34872737 |
Upper-airway cough syndrome | 90.20 | 11.09 | 72 | 83655 | 3486 | 34869718 |
Influenza | 89.35 | 11.09 | 292 | 83435 | 49374 | 34823830 |
Multiple organ dysfunction syndrome | 88.91 | 11.09 | 36 | 83691 | 76530 | 34796674 |
Malignant neoplasm progression | 87.64 | 11.09 | 51 | 83676 | 87995 | 34785209 |
Dyspnoea exertional | 85.68 | 11.09 | 263 | 83464 | 43016 | 34830188 |
Bronchial obstruction | 84.38 | 11.09 | 51 | 83676 | 1565 | 34871639 |
Drug abuse | 83.28 | 11.09 | 69 | 83658 | 99027 | 34774177 |
Neutropenia | 81.88 | 11.09 | 157 | 83570 | 156621 | 34716583 |
Sneezing | 80.73 | 11.09 | 80 | 83647 | 5162 | 34868042 |
Hypersensitivity | 79.44 | 11.09 | 323 | 83404 | 60712 | 34812492 |
Right ventricular hypertrophy | 79.04 | 11.09 | 48 | 83679 | 1486 | 34871718 |
Sensitivity to weather change | 78.99 | 11.09 | 49 | 83678 | 1577 | 34871627 |
Blood creatinine increased | 78.74 | 11.09 | 67 | 83660 | 94909 | 34778295 |
Hyponatraemia | 77.99 | 11.09 | 51 | 83676 | 82640 | 34790564 |
Sepsis | 76.77 | 11.09 | 179 | 83548 | 166382 | 34706822 |
Lower respiratory tract infection | 74.90 | 11.09 | 205 | 83522 | 31432 | 34841772 |
Vital capacity decreased | 74.87 | 11.09 | 30 | 83697 | 362 | 34872842 |
Upper respiratory tract infection | 73.14 | 11.09 | 209 | 83518 | 32850 | 34840354 |
Mood swings | 72.44 | 11.09 | 92 | 83635 | 7809 | 34865395 |
Ear infection | 72.33 | 11.09 | 105 | 83622 | 10126 | 34863078 |
Eosinophilic pneumonia chronic | 72.08 | 11.09 | 27 | 83700 | 268 | 34872936 |
Dysplastic naevus | 71.31 | 11.09 | 31 | 83696 | 465 | 34872739 |
Photodermatosis | 70.69 | 11.09 | 32 | 83695 | 531 | 34872673 |
Allergy to animal | 70.23 | 11.09 | 29 | 83698 | 380 | 34872824 |
Diarrhoea | 69.56 | 11.09 | 599 | 83128 | 389313 | 34483891 |
Breath sounds abnormal | 69.31 | 11.09 | 84 | 83643 | 6797 | 34866407 |
Bronchopulmonary aspergillosis allergic | 69.24 | 11.09 | 37 | 83690 | 892 | 34872312 |
Leukopenia | 69.08 | 11.09 | 32 | 83695 | 62824 | 34810380 |
Solar lentigo | 68.29 | 11.09 | 31 | 83696 | 518 | 34872686 |
Illness | 68.25 | 11.09 | 119 | 83608 | 13410 | 34859794 |
Screaming | 67.76 | 11.09 | 43 | 83684 | 1441 | 34871763 |
Sleep apnoea syndrome | 67.56 | 11.09 | 150 | 83577 | 20171 | 34853033 |
Confusional state | 67.16 | 11.09 | 154 | 83573 | 144006 | 34729198 |
Haemoglobin decreased | 66.54 | 11.09 | 117 | 83610 | 120655 | 34752549 |
Multiple allergies | 66.14 | 11.09 | 56 | 83671 | 2947 | 34870257 |
Osteoporosis | 65.96 | 11.09 | 113 | 83614 | 12555 | 34860649 |
Disease progression | 64.86 | 11.09 | 99 | 83628 | 107978 | 34765226 |
Completed suicide | 64.80 | 11.09 | 84 | 83643 | 98084 | 34775120 |
Vocal cord dysfunction | 64.71 | 11.09 | 22 | 83705 | 160 | 34873044 |
Blood cholesterol | 63.88 | 11.09 | 23 | 83704 | 202 | 34873002 |
Depressed mood | 63.56 | 11.09 | 142 | 83585 | 19175 | 34854029 |
Discomfort | 63.20 | 11.09 | 140 | 83587 | 18798 | 34854406 |
Renal failure | 62.83 | 11.09 | 137 | 83590 | 130420 | 34742784 |
Psychomotor hyperactivity | 62.63 | 11.09 | 95 | 83632 | 9527 | 34863677 |
Respiratory tract congestion | 61.93 | 11.09 | 75 | 83652 | 6064 | 34867140 |
Product dose omission issue | 61.72 | 11.09 | 494 | 83233 | 119217 | 34753987 |
Rhinitis allergic | 61.34 | 11.09 | 54 | 83673 | 2996 | 34870208 |
Social avoidant behaviour | 60.37 | 11.09 | 54 | 83673 | 3060 | 34870144 |
Sputum increased | 60.16 | 11.09 | 48 | 83679 | 2322 | 34870882 |
Insomnia | 59.82 | 11.09 | 440 | 83287 | 103467 | 34769737 |
Headache | 59.56 | 11.09 | 738 | 82989 | 199897 | 34673307 |
Dehydration | 58.01 | 11.09 | 142 | 83585 | 129827 | 34743377 |
Rhabdomyolysis | 57.82 | 11.09 | 47 | 83680 | 68116 | 34805088 |
Obesity | 56.97 | 11.09 | 107 | 83620 | 12771 | 34860433 |
Septic shock | 56.73 | 11.09 | 53 | 83674 | 71781 | 34801423 |
Aortic valve stenosis | 56.66 | 11.09 | 49 | 83678 | 2654 | 34870550 |
Victim of child abuse | 55.61 | 11.09 | 32 | 83695 | 895 | 34872309 |
Rhinitis perennial | 55.52 | 11.09 | 23 | 83704 | 304 | 34872900 |
Nasal disorder | 55.35 | 11.09 | 42 | 83685 | 1886 | 34871318 |
Eye disorder | 54.97 | 11.09 | 89 | 83638 | 9439 | 34863765 |
Renal impairment | 54.40 | 11.09 | 89 | 83638 | 94424 | 34778780 |
Chronic sinusitis | 53.30 | 11.09 | 44 | 83683 | 2235 | 34870969 |
Panic attack | 52.92 | 11.09 | 87 | 83640 | 9345 | 34863859 |
Platelet count decreased | 52.48 | 11.09 | 132 | 83595 | 119585 | 34753619 |
Eye pruritus | 51.69 | 11.09 | 76 | 83651 | 7413 | 34865791 |
Chest X-ray abnormal | 51.49 | 11.09 | 58 | 83669 | 4340 | 34868864 |
Suffocation feeling | 50.89 | 11.09 | 26 | 83701 | 570 | 34872634 |
Pruritus | 49.55 | 11.09 | 539 | 83188 | 141442 | 34731762 |
Educational problem | 49.39 | 11.09 | 25 | 83702 | 537 | 34872667 |
Ascites | 49.20 | 11.09 | 25 | 83702 | 46546 | 34826658 |
Dyspnoea at rest | 49.17 | 11.09 | 53 | 83674 | 3775 | 34869429 |
Eosinophil count | 48.28 | 11.09 | 17 | 83710 | 139 | 34873065 |
Eczema | 48.23 | 11.09 | 124 | 83603 | 18312 | 34854892 |
Anaphylactic reaction | 47.74 | 11.09 | 178 | 83549 | 32123 | 34841081 |
Oropharyngeal pain | 46.31 | 11.09 | 188 | 83539 | 35297 | 34837907 |
Gastrointestinal haemorrhage | 45.79 | 11.09 | 89 | 83638 | 88388 | 34784816 |
General physical health deterioration | 45.64 | 11.09 | 156 | 83571 | 128113 | 34745091 |
Aspirin-exacerbated respiratory disease | 45.46 | 11.09 | 21 | 83706 | 366 | 34872838 |
Product quality issue | 45.00 | 11.09 | 115 | 83612 | 16920 | 34856284 |
Respiratory disorder | 44.76 | 11.09 | 124 | 83603 | 19140 | 34854064 |
Throat clearing | 44.39 | 11.09 | 20 | 83707 | 328 | 34872876 |
Heart rate increased | 44.35 | 11.09 | 224 | 83503 | 46119 | 34827085 |
Hyperkalaemia | 44.12 | 11.09 | 61 | 83666 | 69328 | 34803876 |
Food allergy | 44.02 | 11.09 | 33 | 83694 | 1455 | 34871749 |
Reversible airways obstruction | 43.70 | 11.09 | 22 | 83705 | 467 | 34872737 |
Sputum purulent | 43.40 | 11.09 | 22 | 83705 | 474 | 34872730 |
Cardiac arrest | 42.93 | 11.09 | 105 | 83622 | 96054 | 34777150 |
Personality change | 42.69 | 11.09 | 57 | 83670 | 5082 | 34868122 |
Blood pressure increased | 42.38 | 11.09 | 358 | 83369 | 87744 | 34785460 |
Epidural lipomatosis | 41.90 | 11.09 | 28 | 83699 | 1026 | 34872178 |
Forced vital capacity decreased | 41.84 | 11.09 | 25 | 83702 | 751 | 34872453 |
Product use in unapproved indication | 41.41 | 11.09 | 447 | 83280 | 117052 | 34756152 |
Perfume sensitivity | 41.40 | 11.09 | 14 | 83713 | 100 | 34873104 |
Dust allergy | 40.74 | 11.09 | 26 | 83701 | 880 | 34872324 |
Coma | 40.63 | 11.09 | 30 | 83697 | 45648 | 34827556 |
Bone marrow failure | 40.62 | 11.09 | 10 | 83717 | 29243 | 34843961 |
Myocardial infarction | 40.58 | 11.09 | 151 | 83576 | 120934 | 34752270 |
Negative thoughts | 40.46 | 11.09 | 23 | 83704 | 628 | 34872576 |
Foetal exposure during pregnancy | 39.44 | 11.09 | 21 | 83706 | 38080 | 34835124 |
Nasal inflammation | 38.92 | 11.09 | 17 | 83710 | 258 | 34872946 |
Sinus congestion | 38.86 | 11.09 | 57 | 83670 | 5548 | 34867656 |
Peak expiratory flow rate decreased | 38.68 | 11.09 | 14 | 83713 | 125 | 34873079 |
Hypoventilation | 38.23 | 11.09 | 44 | 83683 | 3370 | 34869834 |
Smoke sensitivity | 38.10 | 11.09 | 14 | 83713 | 131 | 34873073 |
Eye swelling | 38.09 | 11.09 | 78 | 83649 | 9917 | 34863287 |
Cardio-respiratory arrest | 37.81 | 11.09 | 46 | 83681 | 55227 | 34817977 |
Drug resistance | 37.72 | 11.09 | 8 | 83719 | 25919 | 34847285 |
Attention deficit hyperactivity disorder | 37.47 | 11.09 | 38 | 83689 | 2521 | 34870683 |
Intentional overdose | 37.17 | 11.09 | 30 | 83697 | 43644 | 34829560 |
Blood pressure systolic increased | 36.90 | 11.09 | 130 | 83597 | 22822 | 34850382 |
Serotonin syndrome | 36.45 | 11.09 | 3 | 83724 | 19930 | 34853274 |
Respiratory tract infection | 36.42 | 11.09 | 117 | 83610 | 19595 | 34853609 |
Restrictive pulmonary disease | 36.28 | 11.09 | 27 | 83700 | 1177 | 34872027 |
Pleural effusion | 35.65 | 11.09 | 90 | 83637 | 81456 | 34791748 |
Ocular discomfort | 35.54 | 11.09 | 34 | 83693 | 2100 | 34871104 |
Hypokalaemia | 35.21 | 11.09 | 53 | 83674 | 58161 | 34815043 |
Emotional disorder | 35.19 | 11.09 | 55 | 83672 | 5661 | 34867543 |
Nausea | 35.11 | 11.09 | 588 | 83139 | 339320 | 34533884 |
Body temperature decreased | 34.44 | 11.09 | 88 | 83639 | 12946 | 34860258 |
Intervertebral disc degeneration | 34.41 | 11.09 | 58 | 83669 | 6359 | 34866845 |
Diastolic dysfunction | 34.35 | 11.09 | 57 | 83670 | 6170 | 34867034 |
Nasal oedema | 34.11 | 11.09 | 17 | 83710 | 353 | 34872851 |
Anosmia | 33.99 | 11.09 | 45 | 83682 | 3979 | 34869225 |
C-reactive protein increased | 33.95 | 11.09 | 48 | 83679 | 54050 | 34819154 |
Cardiac failure | 33.80 | 11.09 | 109 | 83618 | 91139 | 34782065 |
Lung hyperinflation | 33.61 | 11.09 | 23 | 83704 | 877 | 34872327 |
Agranulocytosis | 33.35 | 11.09 | 8 | 83719 | 23813 | 34849391 |
Suicidal behaviour | 33.14 | 11.09 | 28 | 83699 | 1469 | 34871735 |
Respiratory rate increased | 32.84 | 11.09 | 73 | 83654 | 9821 | 34863383 |
Status asthmaticus | 32.69 | 11.09 | 16 | 83711 | 319 | 34872885 |
Acute myocardial infarction | 31.44 | 11.09 | 50 | 83677 | 53669 | 34819535 |
Morbid thoughts | 31.39 | 11.09 | 14 | 83713 | 224 | 34872980 |
Oesophageal polyp | 31.34 | 11.09 | 10 | 83717 | 58 | 34873146 |
Nasal discharge discolouration | 31.06 | 11.09 | 15 | 83712 | 290 | 34872914 |
Blood test abnormal | 30.93 | 11.09 | 58 | 83669 | 6913 | 34866291 |
Neoplasm progression | 30.40 | 11.09 | 9 | 83718 | 23291 | 34849913 |
Sinus polyp | 30.39 | 11.09 | 13 | 83714 | 187 | 34873017 |
Self-injurious ideation | 30.29 | 11.09 | 28 | 83699 | 1656 | 34871548 |
Metabolic acidosis | 30.24 | 11.09 | 36 | 83691 | 43644 | 34829560 |
Bradycardia | 30.13 | 11.09 | 87 | 83640 | 75331 | 34797873 |
Adjustment disorder | 29.79 | 11.09 | 24 | 83703 | 1177 | 34872027 |
Total lung capacity abnormal | 29.79 | 11.09 | 12 | 83715 | 147 | 34873057 |
International normalised ratio increased | 29.69 | 11.09 | 42 | 83685 | 47285 | 34825919 |
Delirium | 29.67 | 11.09 | 37 | 83690 | 43954 | 34829250 |
Throat irritation | 29.57 | 11.09 | 73 | 83654 | 10512 | 34862692 |
Cytomegalovirus infection | 29.18 | 11.09 | 13 | 83714 | 26122 | 34847082 |
Electrocardiogram QT prolonged | 29.16 | 11.09 | 33 | 83694 | 40919 | 34832285 |
Homicidal ideation | 29.08 | 11.09 | 34 | 83693 | 2648 | 34870556 |
Pneumonia | 28.98 | 11.09 | 1101 | 82626 | 361526 | 34511678 |
Eosinophilic bronchitis | 28.98 | 11.09 | 13 | 83714 | 211 | 34872993 |
Respiratory symptom | 28.74 | 11.09 | 28 | 83699 | 1769 | 34871435 |
Cystic fibrosis | 28.73 | 11.09 | 27 | 83700 | 1631 | 34871573 |
Cardiogenic shock | 28.55 | 11.09 | 14 | 83713 | 26604 | 34846600 |
Cerebral haemorrhage | 28.50 | 11.09 | 25 | 83702 | 34912 | 34838292 |
Prolonged expiration | 28.33 | 11.09 | 13 | 83714 | 223 | 34872981 |
Sinus disorder | 27.84 | 11.09 | 56 | 83671 | 7029 | 34866175 |
Pleural thickening | 27.76 | 11.09 | 15 | 83712 | 370 | 34872834 |
Constipation | 27.73 | 11.09 | 203 | 83524 | 136779 | 34736425 |
Asthenia | 27.71 | 11.09 | 417 | 83310 | 244834 | 34628370 |
Polyp | 27.59 | 11.09 | 40 | 83687 | 3852 | 34869352 |
Syncope | 27.49 | 11.09 | 119 | 83608 | 91332 | 34781872 |
Juvenile idiopathic arthritis | 27.46 | 11.09 | 28 | 83699 | 1869 | 34871335 |
Panic reaction | 27.46 | 11.09 | 25 | 83702 | 1450 | 34871754 |
Forced expiratory volume abnormal | 27.30 | 11.09 | 8 | 83719 | 33 | 34873171 |
Neuroleptic malignant syndrome | 27.21 | 11.09 | 5 | 83722 | 17929 | 34855275 |
Blebitis | 27.17 | 11.09 | 6 | 83721 | 4 | 34873200 |
Eosinophilic oesophagitis | 27.07 | 11.09 | 14 | 83713 | 315 | 34872889 |
Rheumatoid arthritis | 27.03 | 11.09 | 31 | 83696 | 38207 | 34834997 |
Melaena | 26.88 | 11.09 | 27 | 83700 | 35353 | 34837851 |
Encephalopathy | 26.78 | 11.09 | 27 | 83700 | 35292 | 34837912 |
Contraindicated product administered | 26.77 | 11.09 | 9 | 83718 | 21472 | 34851732 |
Endocarditis fibroplastica | 26.60 | 11.09 | 6 | 83721 | 5 | 34873199 |
Mucosal inflammation | 26.56 | 11.09 | 32 | 83695 | 38590 | 34834614 |
Hypoglycaemia | 26.53 | 11.09 | 57 | 83670 | 54583 | 34818621 |
Attention-seeking behaviour | 26.22 | 11.09 | 8 | 83719 | 39 | 34873165 |
Snoring | 26.10 | 11.09 | 36 | 83691 | 3310 | 34869894 |
Decreased appetite | 25.92 | 11.09 | 264 | 83463 | 166128 | 34707076 |
Lactic acidosis | 25.89 | 11.09 | 27 | 83700 | 34745 | 34838459 |
Hepatic failure | 25.50 | 11.09 | 27 | 83700 | 34504 | 34838700 |
Product substitution issue | 25.48 | 11.09 | 67 | 83660 | 10028 | 34863176 |
Nasal discomfort | 25.35 | 11.09 | 25 | 83702 | 1603 | 34871601 |
Excessive eye blinking | 25.03 | 11.09 | 16 | 83711 | 543 | 34872661 |
Blood bilirubin increased | 25.01 | 11.09 | 33 | 83694 | 38263 | 34834941 |
Hypereosinophilic syndrome | 24.99 | 11.09 | 12 | 83715 | 229 | 34872975 |
Throat tightness | 24.80 | 11.09 | 59 | 83668 | 8299 | 34864905 |
Pigment dispersion syndrome | 24.74 | 11.09 | 6 | 83721 | 9 | 34873195 |
Intentional product use issue | 24.63 | 11.09 | 68 | 83659 | 59748 | 34813456 |
Tubulointerstitial nephritis | 24.20 | 11.09 | 10 | 83717 | 21014 | 34852190 |
White blood cell count decreased | 24.17 | 11.09 | 132 | 83595 | 95313 | 34777891 |
Malaise | 23.83 | 11.09 | 598 | 83129 | 185227 | 34687977 |
Alanine aminotransferase increased | 23.78 | 11.09 | 106 | 83621 | 80709 | 34792495 |
Stiff person syndrome | 23.70 | 11.09 | 9 | 83718 | 93 | 34873111 |
Blood lactic acid | 23.62 | 11.09 | 13 | 83714 | 333 | 34872871 |
Stomatitis | 23.55 | 11.09 | 41 | 83686 | 42473 | 34830731 |
Hyperkaliuria | 23.53 | 11.09 | 9 | 83718 | 95 | 34873109 |
Rhonchi | 23.42 | 11.09 | 26 | 83701 | 1914 | 34871290 |
Vomiting | 23.39 | 11.09 | 435 | 83292 | 247186 | 34626018 |
Benign prostatic hyperplasia | 23.21 | 11.09 | 82 | 83645 | 14413 | 34858791 |
Asthma exercise induced | 23.20 | 11.09 | 9 | 83718 | 99 | 34873105 |
Abnormal dreams | 23.03 | 11.09 | 54 | 83673 | 7524 | 34865680 |
Sleep talking | 23.01 | 11.09 | 15 | 83712 | 527 | 34872677 |
Palmar-plantar erythrodysaesthesia syndrome | 22.82 | 11.09 | 6 | 83721 | 16789 | 34856415 |
Respiratory tract irritation | 22.67 | 11.09 | 11 | 83716 | 215 | 34872989 |
Diaphragmatic disorder | 22.55 | 11.09 | 21 | 83706 | 1254 | 34871950 |
Enuresis | 22.53 | 11.09 | 28 | 83699 | 2325 | 34870879 |
Depressed level of consciousness | 22.23 | 11.09 | 43 | 83684 | 42798 | 34830406 |
Meningitis eosinophilic | 22.20 | 11.09 | 6 | 83721 | 17 | 34873187 |
Haematuria | 22.07 | 11.09 | 55 | 83672 | 50011 | 34823193 |
Fear | 21.97 | 11.09 | 65 | 83662 | 10411 | 34862793 |
Behaviour disorder | 21.97 | 11.09 | 41 | 83686 | 4869 | 34868335 |
Gastroenteritis viral | 21.91 | 11.09 | 51 | 83676 | 7073 | 34866131 |
Allergic respiratory disease | 21.88 | 11.09 | 7 | 83720 | 41 | 34873163 |
NPM1 gene mutation | 21.86 | 11.09 | 9 | 83718 | 117 | 34873087 |
Blood immunoglobulin G decreased | 21.80 | 11.09 | 22 | 83705 | 1451 | 34871753 |
Sputum abnormal | 21.67 | 11.09 | 14 | 83713 | 484 | 34872720 |
Haematochezia | 21.40 | 11.09 | 50 | 83677 | 46484 | 34826720 |
Secretion discharge | 21.23 | 11.09 | 45 | 83682 | 5860 | 34867344 |
Haematemesis | 21.22 | 11.09 | 21 | 83706 | 27690 | 34845514 |
Temperature intolerance | 21.16 | 11.09 | 33 | 83694 | 3389 | 34869815 |
Sedation | 21.12 | 11.09 | 12 | 83715 | 20994 | 34852210 |
Child abuse | 21.08 | 11.09 | 13 | 83714 | 414 | 34872790 |
Dysphonia | 20.96 | 11.09 | 111 | 83616 | 23272 | 34849932 |
Obsessive-compulsive disorder | 20.70 | 11.09 | 43 | 83684 | 5521 | 34867683 |
Nasal turbinate abnormality | 20.62 | 11.09 | 6 | 83721 | 24 | 34873180 |
Bronchiolitis obliterans syndrome | 20.58 | 11.09 | 10 | 83717 | 196 | 34873008 |
Fall | 20.54 | 11.09 | 352 | 83375 | 202533 | 34670671 |
Cerebrovascular accident | 20.54 | 11.09 | 119 | 83608 | 84692 | 34788512 |
Acute myeloid leukaemia | 20.53 | 11.09 | 9 | 83718 | 18261 | 34854943 |
Physical assault | 20.52 | 11.09 | 19 | 83708 | 1126 | 34872078 |
Urinary tract infection | 20.35 | 11.09 | 118 | 83609 | 83963 | 34789241 |
Status epilepticus | 20.29 | 11.09 | 3 | 83724 | 12611 | 34860593 |
Injection site pain | 20.08 | 11.09 | 161 | 83566 | 38844 | 34834360 |
Injection site swelling | 20.02 | 11.09 | 67 | 83660 | 11460 | 34861744 |
Blood urea increased | 20.00 | 11.09 | 26 | 83701 | 30338 | 34842866 |
Hypohidrosis | 19.96 | 11.09 | 10 | 83717 | 210 | 34872994 |
Eye irritation | 19.92 | 11.09 | 51 | 83676 | 7510 | 34865694 |
Pyrexia | 19.64 | 11.09 | 628 | 83099 | 332385 | 34540819 |
Pulmonary oedema | 19.59 | 11.09 | 54 | 83673 | 47475 | 34825729 |
Somnambulism | 19.52 | 11.09 | 30 | 83697 | 3042 | 34870162 |
Acute respiratory distress syndrome | 19.52 | 11.09 | 20 | 83707 | 25949 | 34847255 |
Mite allergy | 19.51 | 11.09 | 15 | 83712 | 687 | 34872517 |
Angina pectoris | 19.50 | 11.09 | 28 | 83699 | 31335 | 34841869 |
Lower respiratory tract congestion | 19.40 | 11.09 | 19 | 83708 | 1208 | 34871996 |
Hyperglycaemia | 19.32 | 11.09 | 41 | 83686 | 39439 | 34833765 |
Sopor | 19.26 | 11.09 | 3 | 83724 | 12133 | 34861071 |
Steroid diabetes | 19.24 | 11.09 | 25 | 83702 | 2170 | 34871034 |
Nasal septum deviation | 19.24 | 11.09 | 18 | 83709 | 1081 | 34872123 |
Airway remodelling | 19.18 | 11.09 | 10 | 83717 | 229 | 34872975 |
Cytokine release syndrome | 19.11 | 11.09 | 16 | 83711 | 22861 | 34850343 |
Upper respiratory tract congestion | 19.11 | 11.09 | 16 | 83711 | 829 | 34872375 |
Lung hernia | 19.10 | 11.09 | 7 | 83720 | 65 | 34873139 |
Gout | 19.07 | 11.09 | 94 | 83633 | 19159 | 34854045 |
Hostility | 19.06 | 11.09 | 16 | 83711 | 832 | 34872372 |
Stress | 18.87 | 11.09 | 131 | 83596 | 30216 | 34842988 |
Scleroderma | 18.86 | 11.09 | 21 | 83706 | 1551 | 34871653 |
Forced expiratory flow decreased | 18.83 | 11.09 | 9 | 83718 | 170 | 34873034 |
Unresponsive to stimuli | 18.79 | 11.09 | 23 | 83704 | 27546 | 34845658 |
Pneumocystis jirovecii pneumonia | 18.78 | 11.09 | 12 | 83715 | 19698 | 34853506 |
Hypomagnesaemia | 18.60 | 11.09 | 15 | 83712 | 21836 | 34851368 |
Prostatomegaly | 18.40 | 11.09 | 40 | 83687 | 5301 | 34867903 |
Hypercalcaemia | 18.39 | 11.09 | 7 | 83720 | 15461 | 34857743 |
Self esteem decreased | 18.32 | 11.09 | 13 | 83714 | 526 | 34872678 |
Lung disorder | 18.29 | 11.09 | 144 | 83583 | 34552 | 34838652 |
Oedema peripheral | 18.27 | 11.09 | 191 | 83536 | 119621 | 34753583 |
Bronchitis viral | 18.17 | 11.09 | 10 | 83717 | 256 | 34872948 |
Nasal mucosal disorder | 18.16 | 11.09 | 8 | 83719 | 124 | 34873080 |
Hospitalisation | 17.99 | 11.09 | 212 | 83515 | 56690 | 34816514 |
Altered state of consciousness | 17.93 | 11.09 | 17 | 83710 | 22876 | 34850328 |
Hyperbilirubinaemia | 17.85 | 11.09 | 9 | 83718 | 16834 | 34856370 |
Mental disorder | 17.83 | 11.09 | 78 | 83649 | 15131 | 34858073 |
Drug level increased | 17.79 | 11.09 | 16 | 83711 | 22080 | 34851124 |
Neuritis | 17.72 | 11.09 | 16 | 83711 | 918 | 34872286 |
Nocturnal dyspnoea | 17.68 | 11.09 | 13 | 83714 | 556 | 34872648 |
Ocular hyperaemia | 17.66 | 11.09 | 64 | 83663 | 11388 | 34861816 |
Aspartate aminotransferase increased | 17.56 | 11.09 | 93 | 83634 | 67690 | 34805514 |
Subdural haematoma | 17.41 | 11.09 | 14 | 83713 | 20407 | 34852797 |
Mononeuropathy multiplex | 17.34 | 11.09 | 9 | 83718 | 204 | 34873000 |
Clostridium difficile colitis | 17.28 | 11.09 | 8 | 83719 | 15722 | 34857482 |
Bronchial disorder | 17.28 | 11.09 | 19 | 83708 | 1384 | 34871820 |
Circulatory collapse | 17.22 | 11.09 | 15 | 83712 | 21023 | 34852181 |
COVID-19 | 17.16 | 11.09 | 271 | 83456 | 77279 | 34795925 |
Weight increased | 16.92 | 11.09 | 315 | 83412 | 92718 | 34780486 |
Tearfulness | 16.89 | 11.09 | 26 | 83701 | 2641 | 34870563 |
Hepatic encephalopathy | 16.88 | 11.09 | 7 | 83720 | 14678 | 34858526 |
Bronchopulmonary aspergillosis | 16.83 | 11.09 | 7 | 83720 | 14652 | 34858552 |
Extrapyramidal disorder | 16.76 | 11.09 | 5 | 83722 | 12875 | 34860329 |
Interstitial lung disease | 16.68 | 11.09 | 90 | 83637 | 65192 | 34808012 |
Conjunctivitis | 16.49 | 11.09 | 56 | 83671 | 9649 | 34863555 |
Hypoacusis | 16.44 | 11.09 | 80 | 83647 | 16221 | 34856983 |
Alopecia areata | 16.40 | 11.09 | 9 | 83718 | 229 | 34872975 |
Neutrophil count decreased | 16.28 | 11.09 | 65 | 83662 | 51039 | 34822165 |
Subarachnoid haemorrhage | 16.26 | 11.09 | 5 | 83722 | 12630 | 34860574 |
Chimerism | 16.23 | 11.09 | 9 | 83718 | 234 | 34872970 |
Bronchiolitis | 16.10 | 11.09 | 28 | 83699 | 3148 | 34870056 |
Mast cell activation syndrome | 15.99 | 11.09 | 9 | 83718 | 241 | 34872963 |
Hemiparesis | 15.88 | 11.09 | 9 | 83718 | 15769 | 34857435 |
Diabetic ketoacidosis | 15.83 | 11.09 | 12 | 83715 | 18020 | 34855184 |
Ventricular fibrillation | 15.80 | 11.09 | 19 | 83708 | 22935 | 34850269 |
Renal tubular necrosis | 15.70 | 11.09 | 9 | 83718 | 15671 | 34857533 |
Hepatotoxicity | 15.64 | 11.09 | 17 | 83710 | 21468 | 34851736 |
Generalised anxiety disorder | 15.58 | 11.09 | 14 | 83713 | 798 | 34872406 |
Glaucoma | 15.57 | 11.09 | 44 | 83683 | 6868 | 34866336 |
Poor quality device used | 15.57 | 11.09 | 15 | 83712 | 935 | 34872269 |
Peritonitis | 15.54 | 11.09 | 10 | 83717 | 16355 | 34856849 |
Lymphopenia | 15.49 | 11.09 | 10 | 83717 | 16325 | 34856879 |
Bone density decreased | 15.42 | 11.09 | 21 | 83706 | 1908 | 34871296 |
Affective disorder | 15.42 | 11.09 | 33 | 83694 | 4327 | 34868877 |
Small airways disease | 15.39 | 11.09 | 5 | 83722 | 31 | 34873173 |
Eosinophilic pneumonia | 15.37 | 11.09 | 29 | 83698 | 3472 | 34869732 |
Sputum retention | 15.37 | 11.09 | 11 | 83716 | 451 | 34872753 |
Agitation | 15.22 | 11.09 | 207 | 83520 | 57192 | 34816012 |
Cortisol decreased | 15.17 | 11.09 | 16 | 83711 | 1111 | 34872093 |
Cephalo-pelvic disproportion | 15.11 | 11.09 | 3 | 83724 | 0 | 34873204 |
Exophthalmos congenital | 15.11 | 11.09 | 3 | 83724 | 0 | 34873204 |
Autophobia | 15.11 | 11.09 | 3 | 83724 | 0 | 34873204 |
Pigmentary glaucoma | 15.11 | 11.09 | 3 | 83724 | 0 | 34873204 |
Seizure anoxic | 15.11 | 11.09 | 3 | 83724 | 0 | 34873204 |
ACTH stimulation test abnormal | 15.11 | 11.09 | 3 | 83724 | 0 | 34873204 |
Disseminated intravascular coagulation | 15.08 | 11.09 | 18 | 83709 | 21798 | 34851406 |
Ischaemic stroke | 14.95 | 11.09 | 13 | 83714 | 18237 | 34854967 |
Metastases to liver | 14.93 | 11.09 | 7 | 83720 | 13656 | 34859548 |
Chronic spontaneous urticaria | 14.90 | 11.09 | 7 | 83720 | 127 | 34873077 |
Mycobacterial infection | 14.83 | 11.09 | 23 | 83704 | 2351 | 34870853 |
Electrolyte imbalance | 14.83 | 11.09 | 8 | 83719 | 14404 | 34858800 |
Injection site bruising | 14.73 | 11.09 | 50 | 83677 | 8613 | 34864591 |
Dysarthria | 14.72 | 11.09 | 39 | 83688 | 34743 | 34838461 |
Chronic kidney disease | 14.71 | 11.09 | 50 | 83677 | 41160 | 34832044 |
Oropharyngeal discomfort | 14.69 | 11.09 | 27 | 83700 | 3169 | 34870035 |
Central obesity | 14.65 | 11.09 | 12 | 83715 | 603 | 34872601 |
Frustration tolerance decreased | 14.64 | 11.09 | 24 | 83703 | 2572 | 34870632 |
Allergy to plants | 14.63 | 11.09 | 4 | 83723 | 12 | 34873192 |
Deep vein thrombosis | 14.52 | 11.09 | 94 | 83633 | 65154 | 34808050 |
Treatment failure | 14.50 | 11.09 | 60 | 83667 | 46637 | 34826567 |
Proteinuria | 14.42 | 11.09 | 14 | 83713 | 18628 | 34854576 |
Feeling abnormal | 14.37 | 11.09 | 222 | 83505 | 63013 | 34810191 |
Injection site pruritus | 14.33 | 11.09 | 43 | 83684 | 6940 | 34866264 |
Tachycardia | 14.23 | 11.09 | 132 | 83595 | 84640 | 34788564 |
Haemophilus infection | 14.12 | 11.09 | 16 | 83711 | 1205 | 34871999 |
Eosinophil count abnormal | 14.09 | 11.09 | 9 | 83718 | 305 | 34872899 |
Facial discomfort | 14.08 | 11.09 | 5 | 83722 | 42 | 34873162 |
Liver disorder | 13.96 | 11.09 | 37 | 83690 | 32960 | 34840244 |
Magnetic resonance imaging heart | 13.95 | 11.09 | 4 | 83723 | 15 | 34873189 |
Coronary artery disease | 13.82 | 11.09 | 64 | 83663 | 48241 | 34824963 |
Premature baby | 13.78 | 11.09 | 16 | 83711 | 19617 | 34853587 |
Abdominal pain | 13.74 | 11.09 | 293 | 83434 | 163325 | 34709879 |
Haemodynamic instability | 13.73 | 11.09 | 3 | 83724 | 9520 | 34863684 |
Haematocrit decreased | 13.73 | 11.09 | 36 | 83691 | 32180 | 34841024 |
Stridor | 13.71 | 11.09 | 23 | 83704 | 2511 | 34870693 |
Shock | 13.68 | 11.09 | 23 | 83704 | 24156 | 34849048 |
Total lung capacity decreased | 13.68 | 11.09 | 14 | 83713 | 939 | 34872265 |
Sinus bradycardia | 13.62 | 11.09 | 7 | 83720 | 12956 | 34860248 |
Dacryostenosis congenital | 13.59 | 11.09 | 5 | 83722 | 47 | 34873157 |
Anuria | 13.57 | 11.09 | 4 | 83723 | 10381 | 34862823 |
Duodenal ulcer | 13.46 | 11.09 | 4 | 83723 | 10328 | 34862876 |
Choking | 13.39 | 11.09 | 34 | 83693 | 4981 | 34868223 |
Sinus operation | 13.34 | 11.09 | 12 | 83715 | 685 | 34872519 |
Metastases to lung | 13.30 | 11.09 | 3 | 83724 | 9317 | 34863887 |
Atrioventricular block complete | 13.30 | 11.09 | 3 | 83724 | 9316 | 34863888 |
Vasculitis | 13.29 | 11.09 | 58 | 83669 | 11238 | 34861966 |
Idiopathic intracranial hypertension | 13.28 | 11.09 | 12 | 83715 | 689 | 34872515 |
Atopy | 13.28 | 11.09 | 8 | 83719 | 244 | 34872960 |
Device related infection | 13.27 | 11.09 | 13 | 83714 | 17224 | 34855980 |
Drug reaction with eosinophilia and systemic symptoms | 13.24 | 11.09 | 38 | 83689 | 32974 | 34840230 |
Growth retardation | 13.11 | 11.09 | 19 | 83708 | 1829 | 34871375 |
Disturbance in social behaviour | 13.09 | 11.09 | 19 | 83708 | 1832 | 34871372 |
Migraine | 13.04 | 11.09 | 79 | 83648 | 17399 | 34855805 |
Labelled drug-drug interaction medication error | 13.04 | 11.09 | 10 | 83717 | 14929 | 34858275 |
Cronobacter infection | 13.03 | 11.09 | 4 | 83723 | 20 | 34873184 |
Ear discomfort | 13.01 | 11.09 | 23 | 83704 | 2619 | 34870585 |
Spirometry abnormal | 12.95 | 11.09 | 12 | 83715 | 712 | 34872492 |
Tachypnoea | 12.83 | 11.09 | 15 | 83712 | 18337 | 34854867 |
Synovitis | 12.81 | 11.09 | 9 | 83718 | 14057 | 34859147 |
Intentional self-injury | 12.77 | 11.09 | 66 | 83661 | 13705 | 34859499 |
Overdose | 12.74 | 11.09 | 148 | 83579 | 90911 | 34782293 |
Posterior reversible encephalopathy syndrome | 12.70 | 11.09 | 4 | 83723 | 9950 | 34863254 |
Quality of life decreased | 12.70 | 11.09 | 29 | 83698 | 3972 | 34869232 |
Scratch | 12.60 | 11.09 | 26 | 83701 | 3322 | 34869882 |
Separation anxiety disorder | 12.58 | 11.09 | 3 | 83724 | 4 | 34873200 |
Infusion site swelling | 12.47 | 11.09 | 22 | 83705 | 2502 | 34870702 |
Respiration abnormal | 12.35 | 11.09 | 25 | 83702 | 3151 | 34870053 |
Haemorrhage intracranial | 12.30 | 11.09 | 12 | 83715 | 15934 | 34857270 |
Disease prodromal stage | 12.28 | 11.09 | 4 | 83723 | 25 | 34873179 |
Sudden death | 12.25 | 11.09 | 11 | 83716 | 15190 | 34858014 |
Actinic keratosis | 12.23 | 11.09 | 31 | 83696 | 4536 | 34868668 |
Social problem | 12.23 | 11.09 | 13 | 83714 | 911 | 34872293 |
Onychophagia | 12.21 | 11.09 | 5 | 83722 | 64 | 34873140 |
Fight in school | 12.18 | 11.09 | 3 | 83724 | 5 | 34873199 |
Viral myelitis | 12.14 | 11.09 | 5 | 83722 | 65 | 34873139 |
Lacrimation increased | 11.91 | 11.09 | 46 | 83681 | 8436 | 34864768 |
Kidney infection | 11.82 | 11.09 | 34 | 83693 | 5360 | 34867844 |
Hepatocellular injury | 11.78 | 11.09 | 22 | 83705 | 22189 | 34851015 |
Acne | 11.66 | 11.09 | 55 | 83672 | 11011 | 34862193 |
Prostate cancer | 11.66 | 11.09 | 52 | 83675 | 39597 | 34833607 |
Acute hepatic failure | 11.56 | 11.09 | 10 | 83717 | 14064 | 34859140 |
Dizziness exertional | 11.55 | 11.09 | 7 | 83720 | 216 | 34872988 |
Accidental overdose | 11.54 | 11.09 | 19 | 83708 | 20121 | 34853083 |
Occupational exposure to dust | 11.52 | 11.09 | 3 | 83724 | 7 | 34873197 |
Lymphocyte count decreased | 11.48 | 11.09 | 23 | 83704 | 22599 | 34850605 |
Product dose omission in error | 11.46 | 11.09 | 20 | 83707 | 2254 | 34870950 |
Myoclonus | 11.46 | 11.09 | 11 | 83716 | 14714 | 34858490 |
Hyposmia | 11.43 | 11.09 | 7 | 83720 | 220 | 34872984 |
Oesophagitis | 11.42 | 11.09 | 9 | 83718 | 13252 | 34859952 |
Hyperaesthesia teeth | 11.40 | 11.09 | 10 | 83717 | 552 | 34872652 |
Lymphoma | 11.40 | 11.09 | 8 | 83719 | 12499 | 34860705 |
Pulmonary embolism | 11.38 | 11.09 | 149 | 83578 | 89597 | 34783607 |
Acidosis | 11.37 | 11.09 | 6 | 83721 | 10939 | 34862265 |
Product taste abnormal | 11.29 | 11.09 | 14 | 83713 | 1160 | 34872044 |
Emphysema | 11.28 | 11.09 | 49 | 83678 | 9476 | 34863728 |
Upper gastrointestinal haemorrhage | 11.27 | 11.09 | 28 | 83699 | 25490 | 34847714 |
Dermatitis allergic | 11.25 | 11.09 | 39 | 83688 | 6791 | 34866413 |
Pulmonary artery dilatation | 11.21 | 11.09 | 7 | 83720 | 228 | 34872976 |
Swelling face | 11.15 | 11.09 | 94 | 83633 | 23011 | 34850193 |
Pneumonia aspiration | 11.13 | 11.09 | 57 | 83670 | 41846 | 34831358 |
Myelodysplastic syndrome | 11.12 | 11.09 | 18 | 83709 | 19190 | 34854014 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Asthma | 6745.55 | 9.88 | 4482 | 233825 | 130613 | 79375468 |
Wheezing | 3027.84 | 9.88 | 2622 | 235685 | 114042 | 79392039 |
Eosinophilic granulomatosis with polyangiitis | 1830.55 | 9.88 | 604 | 237703 | 3056 | 79503025 |
Obstructive airways disorder | 1586.97 | 9.88 | 1053 | 237254 | 30406 | 79475675 |
Cough | 1287.74 | 9.88 | 3157 | 235150 | 363632 | 79142449 |
Dyspnoea | 1067.30 | 9.88 | 5212 | 233095 | 851813 | 78654268 |
Full blood count abnormal | 1064.89 | 9.88 | 918 | 237389 | 39556 | 79466525 |
Productive cough | 955.18 | 9.88 | 1247 | 237060 | 87084 | 79418997 |
Forced expiratory volume decreased | 908.06 | 9.88 | 451 | 237856 | 7363 | 79498718 |
Sputum discoloured | 894.22 | 9.88 | 642 | 237665 | 21101 | 79484980 |
Sleep disorder due to a general medical condition | 751.63 | 9.88 | 491 | 237816 | 13786 | 79492295 |
Chest discomfort | 725.27 | 9.88 | 1400 | 236907 | 136644 | 79369437 |
Toxicity to various agents | 686.68 | 9.88 | 204 | 238103 | 421336 | 79084745 |
Nasal congestion | 569.31 | 9.88 | 905 | 237402 | 75647 | 79430434 |
Urticaria | 510.43 | 9.88 | 1459 | 236848 | 183742 | 79322339 |
Nightmare | 485.26 | 9.88 | 486 | 237821 | 25375 | 79480706 |
Nasal polyps | 481.29 | 9.88 | 290 | 238017 | 7037 | 79499044 |
Middle insomnia | 468.85 | 9.88 | 387 | 237920 | 15682 | 79490399 |
Rhinitis allergic | 463.02 | 9.88 | 344 | 237963 | 11925 | 79494156 |
Blood immunoglobulin E increased | 434.06 | 9.88 | 251 | 238056 | 5631 | 79500450 |
Gastrooesophageal reflux disease | 420.49 | 9.88 | 949 | 237358 | 103297 | 79402784 |
Acute kidney injury | 412.20 | 9.88 | 571 | 237736 | 518833 | 78987248 |
Sinusitis | 389.15 | 9.88 | 1377 | 236930 | 194124 | 79311957 |
Bronchitis | 379.14 | 9.88 | 1049 | 237258 | 129595 | 79376486 |
Off label use | 365.34 | 9.88 | 1437 | 236870 | 905778 | 78600303 |
Impaired quality of life | 363.49 | 9.88 | 319 | 237988 | 14067 | 79492014 |
Therapeutic product effect incomplete | 363.33 | 9.88 | 1088 | 237219 | 140557 | 79365524 |
Chronic obstructive pulmonary disease | 359.49 | 9.88 | 791 | 237516 | 84628 | 79421453 |
Synovitis | 336.86 | 9.88 | 31 | 238276 | 150703 | 79355378 |
Food allergy | 326.92 | 9.88 | 266 | 238041 | 10558 | 79495523 |
Seasonal allergy | 316.42 | 9.88 | 313 | 237994 | 16093 | 79489988 |
Abnormal behaviour | 312.12 | 9.88 | 460 | 237847 | 35961 | 79470120 |
Suicidal ideation | 311.16 | 9.88 | 698 | 237609 | 75642 | 79430439 |
Upper respiratory tract infection | 302.96 | 9.88 | 770 | 237537 | 90398 | 79415683 |
Anaemia | 292.02 | 9.88 | 554 | 237753 | 444461 | 79061620 |
Sleep terror | 291.64 | 9.88 | 176 | 238131 | 4282 | 79501799 |
Aggression | 289.83 | 9.88 | 535 | 237772 | 50423 | 79455658 |
Drug interaction | 287.46 | 9.88 | 500 | 237807 | 414683 | 79091398 |
Upper-airway cough syndrome | 282.90 | 9.88 | 253 | 238054 | 11440 | 79494641 |
Loss of personal independence in daily activities | 279.27 | 9.88 | 805 | 237502 | 101775 | 79404306 |
Neutropenia | 276.63 | 9.88 | 271 | 238036 | 287439 | 79218642 |
Breath sounds abnormal | 275.52 | 9.88 | 287 | 238020 | 15697 | 79490384 |
Dyspnoea exertional | 275.49 | 9.88 | 722 | 237585 | 86351 | 79419730 |
Hand deformity | 273.47 | 9.88 | 8 | 238299 | 103911 | 79402170 |
Influenza | 272.57 | 9.88 | 930 | 237377 | 128676 | 79377405 |
Asthmatic crisis | 269.85 | 9.88 | 128 | 238179 | 1878 | 79504203 |
Completed suicide | 269.72 | 9.88 | 204 | 238103 | 245563 | 79260518 |
Pemphigus | 268.34 | 9.88 | 6 | 238301 | 99576 | 79406505 |
Sleep apnoea syndrome | 265.22 | 9.88 | 427 | 237880 | 36051 | 79470030 |
Rhinorrhoea | 255.32 | 9.88 | 645 | 237662 | 75429 | 79430652 |
Pulmonary function test abnormal | 254.18 | 9.88 | 157 | 238150 | 3987 | 79502094 |
Dermatitis atopic | 248.09 | 9.88 | 220 | 238087 | 9836 | 79496245 |
Eosinophil count increased | 242.33 | 9.88 | 277 | 238030 | 16828 | 79489253 |
Eosinophilia | 240.39 | 9.88 | 462 | 237845 | 44883 | 79461198 |
Pancytopenia | 238.86 | 9.88 | 98 | 238209 | 165647 | 79340434 |
Febrile neutropenia | 236.91 | 9.88 | 205 | 238102 | 230794 | 79275287 |
Temperature regulation disorder | 236.42 | 9.88 | 171 | 238136 | 5682 | 79500399 |
Polycystic ovaries | 233.90 | 9.88 | 144 | 238163 | 3635 | 79502446 |
Drug abuse | 233.15 | 9.88 | 97 | 238210 | 162594 | 79343487 |
Blood test abnormal | 219.75 | 9.88 | 268 | 238039 | 17442 | 79488639 |
Anger | 218.31 | 9.88 | 263 | 238044 | 16899 | 79489182 |
Pericarditis | 216.21 | 9.88 | 28 | 238279 | 104208 | 79401873 |
Thrombocytopenia | 215.67 | 9.88 | 286 | 238021 | 264973 | 79241108 |
Hypotension | 213.35 | 9.88 | 643 | 237664 | 439674 | 79066407 |
Respiratory tract infection | 211.74 | 9.88 | 457 | 237850 | 48232 | 79457849 |
Malignant neoplasm progression | 206.58 | 9.88 | 74 | 238233 | 135916 | 79370165 |
Bronchial secretion retention | 205.92 | 9.88 | 137 | 238170 | 3967 | 79502114 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 205.14 | 9.88 | 125 | 238182 | 3096 | 79502985 |
Anxiety | 205.06 | 9.88 | 1358 | 236949 | 247154 | 79258927 |
Infective pulmonary exacerbation of cystic fibrosis | 200.73 | 9.88 | 219 | 238088 | 12632 | 79493449 |
Death | 199.34 | 9.88 | 943 | 237364 | 565571 | 78940510 |
Arthropathy | 189.19 | 9.88 | 151 | 238156 | 176960 | 79329121 |
Headache | 184.98 | 9.88 | 2859 | 235448 | 650913 | 78855168 |
Sensitisation | 184.41 | 9.88 | 118 | 238189 | 3193 | 79502888 |
Treatment failure | 181.29 | 9.88 | 146 | 238161 | 170340 | 79335741 |
Product dose omission issue | 180.80 | 9.88 | 1313 | 236994 | 246224 | 79259857 |
Sneezing | 179.40 | 9.88 | 256 | 238051 | 19427 | 79486654 |
Glossodynia | 179.22 | 9.88 | 44 | 238263 | 103293 | 79402788 |
Systemic lupus erythematosus | 177.19 | 9.88 | 70 | 238237 | 121079 | 79385002 |
Bronchospasm | 175.27 | 9.88 | 287 | 238020 | 24572 | 79481509 |
Anaphylactic reaction | 175.18 | 9.88 | 600 | 237707 | 83143 | 79422938 |
Multiple organ dysfunction syndrome | 175.01 | 9.88 | 70 | 238237 | 120176 | 79385905 |
Joint swelling | 174.87 | 9.88 | 376 | 237931 | 288270 | 79217811 |
Hyponatraemia | 173.76 | 9.88 | 165 | 238142 | 177683 | 79328398 |
Bronchiectasis | 173.70 | 9.88 | 270 | 238037 | 22116 | 79483965 |
Pneumonia | 172.73 | 9.88 | 2850 | 235457 | 657396 | 78848685 |
Secretion discharge | 168.30 | 9.88 | 216 | 238091 | 14806 | 79491275 |
Coeliac disease | 166.19 | 9.88 | 187 | 238120 | 11164 | 79494917 |
Respiratory tract congestion | 165.17 | 9.88 | 248 | 238059 | 19706 | 79486375 |
Rhinitis | 164.46 | 9.88 | 212 | 238095 | 14595 | 79491486 |
Pulmonary function test decreased | 162.88 | 9.88 | 154 | 238153 | 7483 | 79498598 |
Disease progression | 161.09 | 9.88 | 188 | 238119 | 184174 | 79321907 |
Eczema | 160.46 | 9.88 | 368 | 237939 | 40450 | 79465631 |
Rheumatoid factor positive | 159.69 | 9.88 | 4 | 238303 | 59835 | 79446246 |
Helicobacter infection | 159.32 | 9.88 | 13 | 238294 | 69691 | 79436390 |
Contraindicated product administered | 158.81 | 9.88 | 142 | 238165 | 157396 | 79348685 |
General physical health deterioration | 158.17 | 9.88 | 369 | 237938 | 274869 | 79231212 |
Confusional state | 157.78 | 9.88 | 459 | 237848 | 317538 | 79188543 |
Multiple allergies | 157.74 | 9.88 | 175 | 238132 | 10285 | 79495796 |
Oropharyngeal pain | 157.28 | 9.88 | 696 | 237611 | 108657 | 79397424 |
Mood altered | 156.63 | 9.88 | 228 | 238079 | 17619 | 79488462 |
Illness | 152.53 | 9.88 | 391 | 237916 | 46120 | 79459961 |
Sensitivity to weather change | 152.35 | 9.88 | 152 | 238155 | 7895 | 79498186 |
Nasopharyngitis | 151.36 | 9.88 | 1285 | 237022 | 252596 | 79253485 |
Pruritus | 151.17 | 9.88 | 1823 | 236484 | 392825 | 79113256 |
Drug intolerance | 150.24 | 9.88 | 356 | 237951 | 263763 | 79242318 |
Stomatitis | 149.48 | 9.88 | 131 | 238176 | 146626 | 79359455 |
Vital capacity decreased | 148.82 | 9.88 | 83 | 238224 | 1733 | 79504348 |
Crying | 145.16 | 9.88 | 253 | 238054 | 22790 | 79483291 |
Therapeutic product effect decreased | 144.33 | 9.88 | 166 | 238141 | 163697 | 79342384 |
Product quality issue | 143.49 | 9.88 | 315 | 237992 | 33625 | 79472456 |
Sputum increased | 140.64 | 9.88 | 114 | 238193 | 4499 | 79501582 |
Bronchial wall thickening | 139.40 | 9.88 | 91 | 238216 | 2550 | 79503531 |
Intentional product use issue | 138.46 | 9.88 | 150 | 238157 | 151962 | 79354119 |
Eye pruritus | 137.67 | 9.88 | 232 | 238075 | 20338 | 79485743 |
Reversible airways obstruction | 137.44 | 9.88 | 84 | 238223 | 2092 | 79503989 |
Ejection fraction | 136.72 | 9.88 | 85 | 238222 | 2184 | 79503897 |
Renal impairment | 136.64 | 9.88 | 162 | 238145 | 157621 | 79348460 |
Throat clearing | 136.56 | 9.88 | 90 | 238217 | 2564 | 79503517 |
Depression | 135.98 | 9.88 | 1110 | 237197 | 215680 | 79290401 |
Diarrhoea | 133.70 | 9.88 | 1842 | 236465 | 878647 | 78627434 |
C-reactive protein increased | 130.40 | 9.88 | 116 | 238191 | 128911 | 79377170 |
Heart rate increased | 130.36 | 9.88 | 708 | 237599 | 120016 | 79386065 |
Total lung capacity increased | 128.24 | 9.88 | 82 | 238225 | 2216 | 79503865 |
Bronchial obstruction | 126 | 9.88 | 87 | 238220 | 2681 | 79503400 |
Nasal oedema | 125.69 | 9.88 | 73 | 238234 | 1651 | 79504430 |
Septic shock | 123.38 | 9.88 | 111 | 238196 | 122690 | 79383391 |
Sepsis | 122.89 | 9.88 | 404 | 237903 | 269024 | 79237057 |
Perfume sensitivity | 121.04 | 9.88 | 57 | 238250 | 822 | 79505259 |
Intentional overdose | 119.98 | 9.88 | 85 | 238222 | 105875 | 79400206 |
Forced vital capacity decreased | 119.69 | 9.88 | 71 | 238236 | 1672 | 79504409 |
Haemoglobin decreased | 119.55 | 9.88 | 308 | 237999 | 221811 | 79284270 |
Allergy to animal | 118.55 | 9.88 | 66 | 238241 | 1373 | 79504708 |
Folliculitis | 116.97 | 9.88 | 14 | 238293 | 55366 | 79450715 |
Muscle injury | 116.94 | 9.88 | 7 | 238300 | 48554 | 79457527 |
Peak expiratory flow rate decreased | 115.18 | 9.88 | 51 | 238256 | 632 | 79505449 |
Rhabdomyolysis | 115.11 | 9.88 | 84 | 238223 | 103047 | 79403034 |
Impaired healing | 115.09 | 9.88 | 59 | 238248 | 87596 | 79418485 |
Platelet count decreased | 112.56 | 9.88 | 260 | 238047 | 194404 | 79311677 |
Wound | 112.03 | 9.88 | 109 | 238198 | 116070 | 79390011 |
Irritability | 112.01 | 9.88 | 323 | 237984 | 40821 | 79465260 |
Leukopenia | 111.56 | 9.88 | 110 | 238197 | 116403 | 79389678 |
Vocal cord dysfunction | 110.45 | 9.88 | 48 | 238259 | 567 | 79505514 |
Dust allergy | 109.24 | 9.88 | 64 | 238243 | 1472 | 79504609 |
Dysphonia | 108.19 | 9.88 | 395 | 237912 | 56477 | 79449604 |
C-reactive protein abnormal | 107.87 | 9.88 | 10 | 238297 | 48357 | 79457724 |
Infusion related reaction | 107.22 | 9.88 | 342 | 237965 | 229895 | 79276186 |
Insomnia | 106.06 | 9.88 | 1160 | 237147 | 244010 | 79262071 |
Sleep disorder | 106.03 | 9.88 | 522 | 237785 | 85155 | 79420926 |
Lung hyperinflation | 105.39 | 9.88 | 67 | 238240 | 1792 | 79504289 |
Bronchopulmonary aspergillosis allergic | 104.82 | 9.88 | 81 | 238226 | 2980 | 79503101 |
Respiratory rate increased | 103.51 | 9.88 | 211 | 238096 | 21389 | 79484692 |
Sinus congestion | 103.33 | 9.88 | 201 | 238106 | 19695 | 79486386 |
Bronchial hyperreactivity | 103.13 | 9.88 | 80 | 238227 | 2960 | 79503121 |
Mucosal inflammation | 102.05 | 9.88 | 49 | 238258 | 75531 | 79430550 |
Coma | 101.08 | 9.88 | 91 | 238216 | 100558 | 79405523 |
Restrictive pulmonary disease | 100.69 | 9.88 | 74 | 238233 | 2521 | 79503560 |
Blood pressure systolic increased | 100.59 | 9.88 | 432 | 237875 | 66554 | 79439527 |
Sinus disorder | 98.96 | 9.88 | 212 | 238095 | 22252 | 79483829 |
Bone marrow failure | 98.44 | 9.88 | 17 | 238290 | 51090 | 79454991 |
Hyperkalaemia | 97.39 | 9.88 | 119 | 238188 | 114279 | 79391802 |
Rales | 96.58 | 9.88 | 196 | 238111 | 19805 | 79486276 |
Ascites | 96.05 | 9.88 | 53 | 238254 | 75509 | 79430572 |
Blood creatinine increased | 95.47 | 9.88 | 200 | 238107 | 154857 | 79351224 |
Respiratory symptom | 95.35 | 9.88 | 93 | 238214 | 4698 | 79501383 |
Status asthmaticus | 95.08 | 9.88 | 51 | 238256 | 983 | 79505098 |
Right atrial hypertrophy | 94.03 | 9.88 | 46 | 238261 | 725 | 79505356 |
Ear pruritus | 93.58 | 9.88 | 86 | 238221 | 4029 | 79502052 |
Bradycardia | 92.92 | 9.88 | 164 | 238143 | 135393 | 79370688 |
Cardiac arrest | 92.30 | 9.88 | 239 | 238068 | 171857 | 79334224 |
Hypokalaemia | 91.91 | 9.88 | 182 | 238125 | 143858 | 79362223 |
Renal failure | 91.84 | 9.88 | 301 | 238006 | 200667 | 79305414 |
Alopecia | 91.54 | 9.88 | 368 | 237939 | 230987 | 79275094 |
Chronic sinusitis | 91.30 | 9.88 | 150 | 238157 | 12876 | 79493205 |
Rhonchi | 91.10 | 9.88 | 84 | 238223 | 3952 | 79502129 |
Cardio-respiratory arrest | 90.15 | 9.88 | 115 | 238192 | 108395 | 79397686 |
Immunodeficiency | 89.72 | 9.88 | 200 | 238107 | 21568 | 79484513 |
Aspirin-exacerbated respiratory disease | 87.71 | 9.88 | 51 | 238256 | 1156 | 79504925 |
Depressed level of consciousness | 84.98 | 9.88 | 98 | 238209 | 96554 | 79409527 |
Respiratory disorder | 84.85 | 9.88 | 311 | 237996 | 44545 | 79461536 |
Hypoventilation | 84.28 | 9.88 | 106 | 238201 | 7118 | 79498963 |
Cystic fibrosis | 84.20 | 9.88 | 79 | 238228 | 3801 | 79502280 |
Metabolic acidosis | 83.61 | 9.88 | 74 | 238233 | 82455 | 79423626 |
Obstruction | 83.46 | 9.88 | 85 | 238222 | 4525 | 79501556 |
Mood swings | 83.45 | 9.88 | 184 | 238123 | 19696 | 79486385 |
Nasal discharge discolouration | 82.62 | 9.88 | 65 | 238242 | 2456 | 79503625 |
Blood pressure increased | 82.35 | 9.88 | 980 | 237327 | 210380 | 79295701 |
Poor quality device used | 81.61 | 9.88 | 62 | 238245 | 2223 | 79503858 |
Chest X-ray abnormal | 81.55 | 9.88 | 109 | 238198 | 7774 | 79498307 |
Dehydration | 81.36 | 9.88 | 423 | 237884 | 247764 | 79258317 |
Rash erythematous | 80.25 | 9.88 | 364 | 237943 | 57405 | 79448676 |
Respiration abnormal | 79.52 | 9.88 | 107 | 238200 | 7681 | 79498400 |
Gastrointestinal haemorrhage | 79.32 | 9.88 | 205 | 238102 | 147514 | 79358567 |
Decreased appetite | 78.15 | 9.88 | 651 | 237656 | 341767 | 79164314 |
Malaise | 77.90 | 9.88 | 1965 | 236342 | 487904 | 79018177 |
Cardiac failure | 77.80 | 9.88 | 222 | 238085 | 154620 | 79351461 |
Lower respiratory tract infection | 77.40 | 9.88 | 655 | 237652 | 128565 | 79377516 |
Neurotoxicity | 77.36 | 9.88 | 5 | 238302 | 32513 | 79473568 |
Tic | 77.00 | 9.88 | 67 | 238240 | 2919 | 79503162 |
Chronic spontaneous urticaria | 76.67 | 9.88 | 47 | 238260 | 1177 | 79504904 |
Hypersensitivity | 76.56 | 9.88 | 1154 | 237153 | 261085 | 79244996 |
Liver injury | 75.98 | 9.88 | 37 | 238270 | 56577 | 79449504 |
Smoke sensitivity | 75.87 | 9.88 | 37 | 238270 | 579 | 79505502 |
Abnormal dreams | 75.42 | 9.88 | 128 | 238179 | 11284 | 79494797 |
Depressed mood | 75.37 | 9.88 | 316 | 237991 | 48164 | 79457917 |
Throat tightness | 74.91 | 9.88 | 218 | 238089 | 27689 | 79478392 |
Bronchial disorder | 74.80 | 9.88 | 61 | 238246 | 2428 | 79503653 |
Maternal exposure during pregnancy | 74.45 | 9.88 | 188 | 238119 | 136350 | 79369731 |
Throat irritation | 74.20 | 9.88 | 280 | 238027 | 40666 | 79465415 |
Alanine aminotransferase increased | 73.91 | 9.88 | 244 | 238063 | 162326 | 79343755 |
Nasal turbinate hypertrophy | 73.52 | 9.88 | 38 | 238269 | 677 | 79505404 |
Educational problem | 73.33 | 9.88 | 32 | 238275 | 382 | 79505699 |
White blood cell count decreased | 72.89 | 9.88 | 302 | 238005 | 187986 | 79318095 |
Rheumatic fever | 72.22 | 9.88 | 3 | 238304 | 28522 | 79477559 |
Musculoskeletal stiffness | 72.00 | 9.88 | 274 | 238033 | 174734 | 79331347 |
Nasal obstruction | 71.36 | 9.88 | 56 | 238251 | 2108 | 79503973 |
Lacrimation increased | 70.64 | 9.88 | 186 | 238121 | 22291 | 79483790 |
Lactic acidosis | 69.00 | 9.88 | 65 | 238242 | 70294 | 79435787 |
Blister | 68.69 | 9.88 | 160 | 238147 | 119316 | 79386765 |
Emphysema | 68.57 | 9.88 | 151 | 238156 | 16149 | 79489932 |
Ear infection | 67.90 | 9.88 | 242 | 238065 | 34190 | 79471891 |
Prolonged expiration | 67.59 | 9.88 | 44 | 238263 | 1227 | 79504854 |
Neoplasm progression | 67.52 | 9.88 | 35 | 238272 | 51647 | 79454434 |
Agranulocytosis | 67.51 | 9.88 | 25 | 238282 | 45005 | 79461076 |
Frustration tolerance decreased | 66.06 | 9.88 | 96 | 238211 | 7406 | 79498675 |
Delirium | 65.92 | 9.88 | 94 | 238213 | 84533 | 79421548 |
Carpal tunnel syndrome | 65.92 | 9.88 | 166 | 238141 | 19362 | 79486719 |
Encephalopathy | 65.23 | 9.88 | 63 | 238244 | 67334 | 79438747 |
Cytomegalovirus infection | 65.08 | 9.88 | 23 | 238284 | 42621 | 79463460 |
Migraine | 64.85 | 9.88 | 466 | 237841 | 87027 | 79419054 |
Therapy non-responder | 64.77 | 9.88 | 110 | 238197 | 92195 | 79413886 |
Total lung capacity decreased | 64.68 | 9.88 | 60 | 238247 | 2845 | 79503236 |
Sopor | 63.53 | 9.88 | 11 | 238296 | 32999 | 79473082 |
Eosinophilic pneumonia chronic | 63.46 | 9.88 | 31 | 238276 | 487 | 79505594 |
Sinusitis fungal | 62.70 | 9.88 | 54 | 238253 | 2320 | 79503761 |
Right ventricular hypertrophy | 61.98 | 9.88 | 46 | 238261 | 1591 | 79504490 |
Liver disorder | 61.98 | 9.88 | 75 | 238232 | 72342 | 79433739 |
Rhinitis perennial | 61.53 | 9.88 | 27 | 238280 | 327 | 79505754 |
Poor quality sleep | 61.47 | 9.88 | 178 | 238129 | 22544 | 79483537 |
Dyspnoea at rest | 60.78 | 9.88 | 91 | 238216 | 7211 | 79498870 |
Dysplastic naevus | 59.39 | 9.88 | 31 | 238276 | 564 | 79505517 |
Sleep disorder due to general medical condition, insomnia type | 59.16 | 9.88 | 28 | 238279 | 43528 | 79462553 |
Feeling abnormal | 58.87 | 9.88 | 731 | 237576 | 158468 | 79347613 |
Hepatic failure | 58.34 | 9.88 | 58 | 238249 | 61154 | 79444927 |
Bronchial neoplasm | 58.07 | 9.88 | 29 | 238278 | 479 | 79505602 |
Humidity intolerance | 57.92 | 9.88 | 27 | 238280 | 380 | 79505701 |
Hyper IgE syndrome | 57.71 | 9.88 | 30 | 238277 | 541 | 79505540 |
Acute myocardial infarction | 57.63 | 9.88 | 88 | 238219 | 76948 | 79429133 |
Idiopathic intracranial hypertension | 57.59 | 9.88 | 59 | 238248 | 3163 | 79502918 |
Red blood cell sedimentation rate increased | 57.27 | 9.88 | 33 | 238274 | 45909 | 79460172 |
Pulmonary mass | 57.20 | 9.88 | 204 | 238103 | 28830 | 79477251 |
Angioedema | 55.79 | 9.88 | 404 | 237903 | 75631 | 79430450 |
Scratch | 55.53 | 9.88 | 94 | 238213 | 8269 | 79497812 |
Aspartate aminotransferase increased | 55.13 | 9.88 | 220 | 238087 | 138421 | 79367660 |
Burning sensation | 54.82 | 9.88 | 331 | 237976 | 58301 | 79447780 |
Salpingo-oophorectomy unilateral | 54.74 | 9.88 | 33 | 238274 | 801 | 79505280 |
Palmar-plantar erythrodysaesthesia syndrome | 53.87 | 9.88 | 16 | 238291 | 33118 | 79472963 |
Abdominal discomfort | 53.47 | 9.88 | 485 | 237822 | 250242 | 79255839 |
Drug resistance | 53.08 | 9.88 | 30 | 238277 | 42183 | 79463898 |
Neutropenic sepsis | 52.13 | 9.88 | 9 | 238298 | 27055 | 79479026 |
Acute myeloid leukaemia | 51.91 | 9.88 | 14 | 238293 | 30871 | 79475210 |
Hypoglycaemia | 51.50 | 9.88 | 145 | 238162 | 101449 | 79404632 |
Hypomagnesaemia | 51.31 | 9.88 | 39 | 238268 | 46872 | 79459209 |
Neuroleptic malignant syndrome | 51.28 | 9.88 | 10 | 238297 | 27549 | 79478532 |
Screaming | 51.21 | 9.88 | 61 | 238246 | 3872 | 79502209 |
Viral infection | 51.02 | 9.88 | 259 | 238048 | 42757 | 79463324 |
Nasal inflammation | 50.93 | 9.88 | 30 | 238277 | 697 | 79505384 |
International normalised ratio increased | 50.70 | 9.88 | 111 | 238196 | 84610 | 79421471 |
Body tinea | 50.66 | 9.88 | 43 | 238264 | 1811 | 79504270 |
Psychomotor hyperactivity | 50.50 | 9.88 | 137 | 238170 | 16712 | 79489369 |
Rheumatoid arthritis | 50.43 | 9.88 | 390 | 237917 | 208080 | 79298001 |
Acute respiratory distress syndrome | 50.33 | 9.88 | 35 | 238272 | 44032 | 79462049 |
Melaena | 50.08 | 9.88 | 65 | 238242 | 60825 | 79445256 |
Blood creatine phosphokinase increased | 49.91 | 9.88 | 75 | 238232 | 66015 | 79440066 |
Cardiac murmur | 49.78 | 9.88 | 131 | 238176 | 15693 | 79490388 |
Ejection fraction abnormal | 49.75 | 9.88 | 48 | 238259 | 2392 | 79503689 |
Serotonin syndrome | 48.53 | 9.88 | 38 | 238269 | 44989 | 79461092 |
Victim of child abuse | 48.26 | 9.88 | 32 | 238275 | 921 | 79505160 |
Sputum culture positive | 48.18 | 9.88 | 58 | 238249 | 3723 | 79502358 |
Swelling face | 48.07 | 9.88 | 371 | 237936 | 70841 | 79435240 |
Photodermatosis | 47.93 | 9.88 | 32 | 238275 | 932 | 79505149 |
Hepatocellular injury | 47.81 | 9.88 | 43 | 238264 | 47550 | 79458531 |
Mastocytosis | 47.79 | 9.88 | 26 | 238281 | 516 | 79505565 |
Urticaria chronic | 47.77 | 9.88 | 27 | 238280 | 579 | 79505502 |
Irritable bowel syndrome | 47.62 | 9.88 | 70 | 238237 | 62171 | 79443910 |
Sedation | 47.39 | 9.88 | 51 | 238256 | 51844 | 79454237 |
Aphonia | 47.37 | 9.88 | 99 | 238208 | 10213 | 79495868 |
Body temperature decreased | 47.24 | 9.88 | 206 | 238101 | 31939 | 79474142 |
Cardiogenic shock | 46.94 | 9.88 | 34 | 238273 | 41880 | 79464201 |
Skin plaque | 46.86 | 9.88 | 101 | 238206 | 10644 | 79495437 |
Mononeuropathy multiplex | 46.51 | 9.88 | 24 | 238283 | 426 | 79505655 |
Toxic epidermal necrolysis | 46.33 | 9.88 | 39 | 238268 | 44542 | 79461539 |
Neutrophil count decreased | 46.24 | 9.88 | 136 | 238171 | 93823 | 79412258 |
Mast cell activation syndrome | 46 | 9.88 | 28 | 238279 | 692 | 79505389 |
Drug level increased | 45.94 | 9.88 | 31 | 238276 | 39620 | 79466461 |
Nephrectomy | 45.77 | 9.88 | 43 | 238264 | 2072 | 79504009 |
Myocardial infarction | 45.70 | 9.88 | 342 | 237965 | 183787 | 79322294 |
Solar lentigo | 45.53 | 9.88 | 33 | 238274 | 1100 | 79504981 |
Eye swelling | 45.50 | 9.88 | 178 | 238129 | 26290 | 79479791 |
Bursitis | 45.48 | 9.88 | 220 | 238087 | 35624 | 79470457 |
Metastases to liver | 45.44 | 9.88 | 14 | 238293 | 28300 | 79477781 |
Disseminated intravascular coagulation | 44.31 | 9.88 | 26 | 238281 | 35816 | 79470265 |
Interstitial lung disease | 43.31 | 9.88 | 181 | 238126 | 112419 | 79393662 |
Cytokine release syndrome | 43.27 | 9.88 | 27 | 238280 | 35971 | 79470110 |
Anosmia | 43.09 | 9.88 | 87 | 238220 | 8757 | 79497324 |
Diastolic dysfunction | 43.06 | 9.88 | 98 | 238209 | 10713 | 79495368 |
Sarcoidosis | 43.03 | 9.88 | 84 | 238223 | 8251 | 79497830 |
Rash maculo-papular | 42.97 | 9.88 | 63 | 238244 | 56015 | 79450066 |
Social avoidant behaviour | 42.97 | 9.88 | 62 | 238245 | 4752 | 79501329 |
Circulatory collapse | 42.91 | 9.88 | 30 | 238277 | 37638 | 79468443 |
Endometrial ablation | 42.86 | 9.88 | 29 | 238278 | 864 | 79505217 |
Stress | 42.72 | 9.88 | 394 | 237913 | 79218 | 79426863 |
Eosinophil count | 42.50 | 9.88 | 16 | 238291 | 126 | 79505955 |
Haematochezia | 42.31 | 9.88 | 128 | 238179 | 87517 | 79418564 |
Pleural effusion | 41.92 | 9.88 | 258 | 238049 | 145004 | 79361077 |
Inflammation | 41.04 | 9.88 | 143 | 238164 | 93610 | 79412471 |
Electrocardiogram QT prolonged | 40.83 | 9.88 | 136 | 238171 | 90250 | 79415831 |
Colitis | 40.68 | 9.88 | 100 | 238207 | 73207 | 79432874 |
Rheumatoid nodule | 40.55 | 9.88 | 3 | 238304 | 17435 | 79488646 |
Haemophagocytic lymphohistiocytosis | 40.47 | 9.88 | 8 | 238299 | 21829 | 79484252 |
Nasal disorder | 40.35 | 9.88 | 53 | 238254 | 3716 | 79502365 |
Anuria | 40.31 | 9.88 | 7 | 238300 | 20956 | 79485125 |
Ear discomfort | 40.13 | 9.88 | 83 | 238224 | 8500 | 79497581 |
COVID-19 | 39.63 | 9.88 | 677 | 237630 | 156997 | 79349084 |
Erythema | 39.41 | 9.88 | 909 | 237398 | 222381 | 79283700 |
Negative thoughts | 39.36 | 9.88 | 33 | 238274 | 1366 | 79504715 |
Metastases to bone | 39.34 | 9.88 | 12 | 238295 | 24415 | 79481666 |
Product use in unapproved indication | 39.31 | 9.88 | 1003 | 237304 | 249356 | 79256725 |
Cerebral haemorrhage | 39.30 | 9.88 | 70 | 238237 | 57603 | 79448478 |
Suffocation feeling | 39.22 | 9.88 | 36 | 238271 | 1684 | 79504397 |
Personality change | 39.20 | 9.88 | 91 | 238216 | 10079 | 79496002 |
Hepatic enzyme increased | 39.01 | 9.88 | 353 | 237954 | 182257 | 79323824 |
Bone erosion | 38.98 | 9.88 | 4 | 238303 | 17843 | 79488238 |
Hepatic function abnormal | 38.81 | 9.88 | 102 | 238205 | 73005 | 79433076 |
Blood urea increased | 38.18 | 9.88 | 54 | 238253 | 48736 | 79457345 |
FEV1/FVC ratio decreased | 38.09 | 9.88 | 17 | 238290 | 215 | 79505866 |
Haemoptysis | 37.93 | 9.88 | 292 | 238015 | 55707 | 79450374 |
Product substitution issue | 37.93 | 9.88 | 140 | 238167 | 20116 | 79485965 |
Infection susceptibility increased | 37.80 | 9.88 | 51 | 238256 | 3670 | 79502411 |
Eosinophilic oesophagitis | 37.69 | 9.88 | 23 | 238284 | 571 | 79505510 |
Injection site pain | 37.69 | 9.88 | 571 | 237736 | 129267 | 79376814 |
Haemodynamic instability | 37.69 | 9.88 | 4 | 238303 | 17378 | 79488703 |
Pneumonia aspiration | 37.43 | 9.88 | 91 | 238216 | 66876 | 79439205 |
Cardiac disorder | 37.10 | 9.88 | 329 | 237978 | 65428 | 79440653 |
Eosinophilic pneumonia | 37.01 | 9.88 | 61 | 238246 | 5249 | 79500832 |
Drug reaction with eosinophilia and systemic symptoms | 36.95 | 9.88 | 86 | 238221 | 64158 | 79441923 |
Blood pressure fluctuation | 36.94 | 9.88 | 92 | 238215 | 67053 | 79439028 |
Nausea | 36.72 | 9.88 | 2417 | 235890 | 954779 | 78551302 |
Mite allergy | 36.66 | 9.88 | 30 | 238277 | 1200 | 79504881 |
Skin ulcer | 36.65 | 9.88 | 66 | 238241 | 54084 | 79451997 |
Osteoporosis | 36.56 | 9.88 | 282 | 238025 | 53830 | 79452251 |
Respiratory tract inflammation | 36.52 | 9.88 | 26 | 238281 | 842 | 79505239 |
Lower respiratory tract congestion | 36.44 | 9.88 | 52 | 238255 | 3945 | 79502136 |
Eosinophilic bronchitis | 36.31 | 9.88 | 21 | 238286 | 471 | 79505610 |
Poisoning | 36.28 | 9.88 | 15 | 238292 | 25257 | 79480824 |
Transplant rejection | 36.28 | 9.88 | 7 | 238300 | 19430 | 79486651 |
Heart sounds | 36.25 | 9.88 | 27 | 238280 | 939 | 79505142 |
Nervousness | 36.05 | 9.88 | 196 | 238111 | 33219 | 79472862 |
Atopy | 35.76 | 9.88 | 20 | 238287 | 420 | 79505661 |
Cholestasis | 35.73 | 9.88 | 63 | 238244 | 52046 | 79454035 |
Separation anxiety disorder | 35.43 | 9.88 | 10 | 238297 | 26 | 79506055 |
Gastrointestinal disorder | 35.29 | 9.88 | 217 | 238090 | 121988 | 79384093 |
Neuropsychiatric symptoms | 34.99 | 9.88 | 31 | 238276 | 1384 | 79504697 |
Accidental overdose | 34.93 | 9.88 | 40 | 238267 | 39541 | 79466540 |
Bronchial haemorrhage | 34.81 | 9.88 | 30 | 238277 | 1290 | 79504791 |
Blood cholesterol | 34.69 | 9.88 | 23 | 238284 | 662 | 79505419 |
Epidural lipomatosis | 34.62 | 9.88 | 29 | 238278 | 1199 | 79504882 |
Live birth | 34.46 | 9.88 | 7 | 238300 | 18737 | 79487344 |
Tubulointerstitial nephritis | 34.44 | 9.88 | 38 | 238269 | 38197 | 79467884 |
Neuropathy peripheral | 34.32 | 9.88 | 264 | 238043 | 141041 | 79365040 |
Hypereosinophilic syndrome | 34.22 | 9.88 | 21 | 238286 | 527 | 79505554 |
Pharyngeal swelling | 34.17 | 9.88 | 73 | 238234 | 7646 | 79498435 |
Respiratory tract irritation | 34.13 | 9.88 | 22 | 238285 | 603 | 79505478 |
Lipohypertrophy | 33.83 | 9.88 | 25 | 238282 | 859 | 79505222 |
Affective disorder | 33.79 | 9.88 | 76 | 238231 | 8243 | 79497838 |
Somnambulism | 33.69 | 9.88 | 61 | 238246 | 5660 | 79500421 |
Joint range of motion decreased | 33.51 | 9.88 | 30 | 238277 | 33252 | 79472829 |
Infusion site swelling | 33.49 | 9.88 | 73 | 238234 | 7753 | 79498328 |
Ischaemic stroke | 33.20 | 9.88 | 30 | 238277 | 33101 | 79472980 |
Cognitive disorder | 33.12 | 9.88 | 103 | 238204 | 69823 | 79436258 |
Creatinine renal clearance decreased | 33.11 | 9.88 | 8 | 238299 | 18994 | 79487087 |
Hyperbilirubinaemia | 32.93 | 9.88 | 16 | 238291 | 24502 | 79481579 |
Altered state of consciousness | 32.83 | 9.88 | 50 | 238257 | 43772 | 79462309 |
Asthenia | 32.67 | 9.88 | 1225 | 237082 | 510464 | 78995617 |
Hypercalcaemia | 32.67 | 9.88 | 40 | 238267 | 38390 | 79467691 |
Unresponsive to stimuli | 32.63 | 9.88 | 74 | 238233 | 55714 | 79450367 |
Clostridium difficile colitis | 32.63 | 9.88 | 29 | 238278 | 32254 | 79473827 |
Lymphocyte count decreased | 32.58 | 9.88 | 57 | 238250 | 47232 | 79458849 |
Bacteraemia | 32.56 | 9.88 | 30 | 238277 | 32794 | 79473287 |
Gamma-glutamyltransferase increased | 32.41 | 9.88 | 72 | 238235 | 54608 | 79451473 |
Biliary dyskinesia | 32.36 | 9.88 | 39 | 238268 | 2506 | 79503575 |
Hysterectomy | 32.12 | 9.88 | 63 | 238244 | 6209 | 79499872 |
Hepatic encephalopathy | 32.11 | 9.88 | 16 | 238291 | 24150 | 79481931 |
Sinus polyp | 32.03 | 9.88 | 20 | 238287 | 518 | 79505563 |
Pneumocystis jirovecii pneumonia | 31.91 | 9.88 | 30 | 238277 | 32478 | 79473603 |
Fluid retention | 31.85 | 9.88 | 334 | 237973 | 69475 | 79436606 |
Hip arthroplasty | 31.70 | 9.88 | 36 | 238271 | 35720 | 79470361 |
Prescribed underdose | 31.69 | 9.88 | 25 | 238282 | 29489 | 79476592 |
Forced expiratory flow decreased | 31.57 | 9.88 | 16 | 238291 | 273 | 79505808 |
Subarachnoid haemorrhage | 31.32 | 9.88 | 17 | 238290 | 24448 | 79481633 |
Airway remodelling | 31.31 | 9.88 | 16 | 238291 | 278 | 79505803 |
Temperature intolerance | 31.20 | 9.88 | 81 | 238226 | 9624 | 79496457 |
Nephropathy toxic | 31.18 | 9.88 | 11 | 238296 | 20408 | 79485673 |
Lung diffusion test decreased | 31.00 | 9.88 | 28 | 238279 | 1282 | 79504799 |
Orthostatic hypotension | 30.86 | 9.88 | 77 | 238230 | 56087 | 79449994 |
Increased viscosity of bronchial secretion | 30.84 | 9.88 | 20 | 238287 | 554 | 79505527 |
Overdose | 30.83 | 9.88 | 377 | 237930 | 183829 | 79322252 |
Osteonecrosis of jaw | 30.79 | 9.88 | 51 | 238256 | 43175 | 79462906 |
Proteinuria | 30.73 | 9.88 | 31 | 238276 | 32471 | 79473610 |
Polyp | 30.65 | 9.88 | 72 | 238235 | 8035 | 79498046 |
Eye disorder | 30.65 | 9.88 | 145 | 238162 | 23267 | 79482814 |
Diabetic ketoacidosis | 30.64 | 9.88 | 34 | 238273 | 34088 | 79471993 |
Acute hepatic failure | 30.49 | 9.88 | 27 | 238280 | 30086 | 79475995 |
Vasculitis | 30.37 | 9.88 | 152 | 238155 | 24950 | 79481131 |
Hereditary angioedema | 30.30 | 9.88 | 56 | 238251 | 5279 | 79500802 |
Panic attack | 30.27 | 9.88 | 148 | 238159 | 24068 | 79482013 |
Lung disorder | 30.23 | 9.88 | 371 | 237936 | 80186 | 79425895 |
Cholecystitis chronic | 30.14 | 9.88 | 81 | 238226 | 9825 | 79496256 |
Pharyngitis streptococcal | 30.02 | 9.88 | 85 | 238222 | 10629 | 79495452 |
Respiratory arrest | 30.01 | 9.88 | 81 | 238226 | 57469 | 79448612 |
Increased bronchial secretion | 29.91 | 9.88 | 43 | 238264 | 3284 | 79502797 |
Snoring | 29.84 | 9.88 | 57 | 238250 | 5509 | 79500572 |
Renal tubular necrosis | 29.79 | 9.88 | 19 | 238288 | 25020 | 79481061 |
Oropharyngeal discomfort | 29.71 | 9.88 | 66 | 238241 | 7100 | 79498981 |
Psoriatic arthropathy | 29.61 | 9.88 | 126 | 238181 | 77873 | 79428208 |
Drug-induced liver injury | 29.50 | 9.88 | 100 | 238207 | 66017 | 79440064 |
Inhibitory drug interaction | 29.50 | 9.88 | 50 | 238257 | 4403 | 79501678 |
Cytopenia | 29.42 | 9.88 | 12 | 238295 | 20371 | 79485710 |
Oral allergy syndrome | 29.40 | 9.88 | 11 | 238296 | 85 | 79505996 |
Hypocalcaemia | 29.38 | 9.88 | 66 | 238241 | 49858 | 79456223 |
Sinus operation | 29.38 | 9.88 | 37 | 238270 | 2488 | 79503593 |
Frequent bowel movements | 29.30 | 9.88 | 27 | 238280 | 29512 | 79476569 |
Forced expiratory volume abnormal | 29.29 | 9.88 | 12 | 238295 | 121 | 79505960 |
Laryngeal stenosis | 29.25 | 9.88 | 25 | 238282 | 1063 | 79505018 |
Morbid thoughts | 29.17 | 9.88 | 22 | 238285 | 780 | 79505301 |
Metastases to lung | 29.11 | 9.88 | 9 | 238298 | 18154 | 79487927 |
Vomiting | 29.02 | 9.88 | 1661 | 236646 | 664167 | 78841914 |
Blood bilirubin increased | 29.00 | 9.88 | 101 | 238206 | 66131 | 79439950 |
Skin necrosis | 28.92 | 9.88 | 9 | 238298 | 18078 | 79488003 |
Quality of life decreased | 28.54 | 9.88 | 82 | 238225 | 10338 | 79495743 |
Total lung capacity abnormal | 28.54 | 9.88 | 14 | 238293 | 222 | 79505859 |
Hepatotoxicity | 28.53 | 9.88 | 70 | 238237 | 51282 | 79454799 |
Self-injurious ideation | 28.39 | 9.88 | 44 | 238263 | 3594 | 79502487 |
Progressive multifocal leukoencephalopathy | 28.35 | 9.88 | 13 | 238294 | 20587 | 79485494 |
Swelling | 28.32 | 9.88 | 466 | 237841 | 216245 | 79289836 |
Infusion site pruritus | 28.29 | 9.88 | 47 | 238260 | 4071 | 79502010 |
Haematuria | 28.14 | 9.88 | 108 | 238199 | 68728 | 79437353 |
Drug tolerance decreased | 28.11 | 9.88 | 3 | 238304 | 12975 | 79493106 |
Immune reconstitution inflammatory syndrome | 28.02 | 9.88 | 4 | 238303 | 13837 | 79492244 |
Nocturnal fear | 27.95 | 9.88 | 7 | 238300 | 9 | 79506072 |
Prostate cancer | 27.89 | 9.88 | 35 | 238272 | 33233 | 79472848 |
Medication error | 27.87 | 9.88 | 108 | 238199 | 68534 | 79437547 |
Condition aggravated | 27.84 | 9.88 | 1219 | 237088 | 499905 | 79006176 |
Spirometry abnormal | 27.77 | 9.88 | 23 | 238284 | 936 | 79505145 |
Influenza like illness | 27.67 | 9.88 | 332 | 237975 | 71375 | 79434706 |
Glucose tolerance impaired | 27.58 | 9.88 | 69 | 238238 | 8015 | 79498066 |
Mobility decreased | 27.49 | 9.88 | 233 | 238074 | 121942 | 79384139 |
Intentional product misuse | 27.46 | 9.88 | 169 | 238138 | 94996 | 79411085 |
Infusion site erythema | 27.43 | 9.88 | 76 | 238231 | 9384 | 79496697 |
Peritonitis | 27.37 | 9.88 | 26 | 238281 | 28010 | 79478071 |
Extrapyramidal disorder | 27.27 | 9.88 | 17 | 238290 | 22662 | 79483419 |
Blood alkaline phosphatase increased | 27.26 | 9.88 | 98 | 238209 | 63566 | 79442515 |
Fear | 27.21 | 9.88 | 134 | 238173 | 21852 | 79484229 |
Cerebral infarction | 27.19 | 9.88 | 60 | 238247 | 45616 | 79460465 |
Status epilepticus | 27.15 | 9.88 | 21 | 238286 | 25020 | 79481061 |
Second primary malignancy | 27.14 | 9.88 | 5 | 238302 | 14345 | 79491736 |
Inappropriate schedule of product administration | 27.08 | 9.88 | 555 | 237752 | 133073 | 79373008 |
Lymphopenia | 26.83 | 9.88 | 31 | 238276 | 30526 | 79475555 |
Atrioventricular block first degree | 26.77 | 9.88 | 3 | 238304 | 12488 | 79493593 |
Injection site pruritus | 26.72 | 9.88 | 217 | 238090 | 42066 | 79464015 |
Pneumothorax spontaneous | 26.67 | 9.88 | 27 | 238280 | 1427 | 79504654 |
Sputum purulent | 26.50 | 9.88 | 26 | 238281 | 1323 | 79504758 |
Bronchospasm paradoxical | 26.45 | 9.88 | 12 | 238295 | 158 | 79505923 |
Electrolyte imbalance | 26.40 | 9.88 | 32 | 238275 | 30849 | 79475232 |
Weight decreased | 26.35 | 9.88 | 1306 | 237001 | 353892 | 79152189 |
Sinus bradycardia | 26.34 | 9.88 | 22 | 238285 | 25225 | 79480856 |
Upper limb fracture | 26.29 | 9.88 | 115 | 238192 | 17852 | 79488229 |
Emotional distress | 26.28 | 9.88 | 207 | 238100 | 39762 | 79466319 |
Neurosensory hypoacusis | 25.91 | 9.88 | 13 | 238294 | 217 | 79505864 |
Haemodialysis | 25.74 | 9.88 | 11 | 238296 | 18157 | 79487924 |
Jaundice | 25.68 | 9.88 | 78 | 238229 | 53271 | 79452810 |
Rectal haemorrhage | 25.56 | 9.88 | 129 | 238178 | 76171 | 79429910 |
Incorrect dose administered | 25.42 | 9.88 | 345 | 237962 | 76285 | 79429796 |
Lip swelling | 25.34 | 9.88 | 209 | 238098 | 40702 | 79465379 |
Swollen tongue | 25.05 | 9.88 | 215 | 238092 | 42355 | 79463726 |
Miosis | 24.99 | 9.88 | 8 | 238299 | 15781 | 79490300 |
Posterior reversible encephalopathy syndrome | 24.93 | 9.88 | 25 | 238282 | 26256 | 79479825 |
Emotional disorder | 24.92 | 9.88 | 97 | 238210 | 14290 | 79491791 |
Haemorrhage intracranial | 24.75 | 9.88 | 25 | 238282 | 26168 | 79479913 |
Thinking abnormal | 24.67 | 9.88 | 91 | 238216 | 13070 | 79493011 |
Ulcer | 24.64 | 9.88 | 32 | 238275 | 29940 | 79476141 |
Dysarthria | 24.59 | 9.88 | 111 | 238196 | 67511 | 79438570 |
Blood cholesterol increased | 23.99 | 9.88 | 149 | 238158 | 83571 | 79422510 |
Attention-seeking behaviour | 23.97 | 9.88 | 10 | 238297 | 106 | 79505975 |
Torsade de pointes | 23.89 | 9.88 | 14 | 238293 | 19298 | 79486783 |
Chronic kidney disease | 23.82 | 9.88 | 109 | 238198 | 66045 | 79440036 |
Stevens-Johnson syndrome | 23.69 | 9.88 | 51 | 238256 | 39115 | 79466966 |
Oesophageal polyp | 23.68 | 9.88 | 9 | 238298 | 73 | 79506008 |
Febrile bone marrow aplasia | 23.65 | 9.88 | 5 | 238302 | 13015 | 79493066 |
Acute generalised exanthematous pustulosis | 23.57 | 9.88 | 11 | 238296 | 17243 | 79488838 |
Facet joint syndrome | 23.51 | 9.88 | 3 | 238304 | 11299 | 79494782 |
Diffuse large B-cell lymphoma | 23.49 | 9.88 | 4 | 238303 | 12145 | 79493936 |
Embolism venous | 23.46 | 9.88 | 44 | 238263 | 4195 | 79501886 |
Blebitis | 23.43 | 9.88 | 6 | 238301 | 9 | 79506072 |
Coagulopathy | 23.38 | 9.88 | 45 | 238262 | 35961 | 79470120 |
Haematemesis | 23.35 | 9.88 | 79 | 238228 | 52185 | 79453896 |
Upper gastrointestinal haemorrhage | 23.31 | 9.88 | 56 | 238251 | 41324 | 79464757 |
Tachycardia | 23.31 | 9.88 | 382 | 237925 | 177386 | 79328695 |
Neurodevelopmental disorder | 23.10 | 9.88 | 8 | 238299 | 48 | 79506033 |
Metastases to central nervous system | 23.06 | 9.88 | 10 | 238297 | 16365 | 79489716 |
Urinary retention | 23.05 | 9.88 | 89 | 238218 | 56541 | 79449540 |
Attention deficit hyperactivity disorder | 23.05 | 9.88 | 38 | 238269 | 3271 | 79502810 |
Pulmonary pain | 22.99 | 9.88 | 45 | 238262 | 4428 | 79501653 |
Hypoalbuminaemia | 22.92 | 9.88 | 18 | 238289 | 21279 | 79484802 |
Enuresis | 22.83 | 9.88 | 37 | 238270 | 3139 | 79502942 |
Liver function test abnormal | 22.76 | 9.88 | 107 | 238200 | 64368 | 79441713 |
Tenosynovitis | 22.71 | 9.88 | 9 | 238298 | 15545 | 79490536 |
Injection site scab | 22.68 | 9.88 | 14 | 238293 | 355 | 79505726 |
Knee arthroplasty | 22.45 | 9.88 | 61 | 238246 | 43187 | 79462894 |
Infusion site haemorrhage | 22.34 | 9.88 | 40 | 238267 | 3680 | 79502401 |
Sputum abnormal | 22.31 | 9.88 | 23 | 238284 | 1242 | 79504839 |
Nasal mucosal disorder | 22.30 | 9.88 | 14 | 238293 | 366 | 79505715 |
Appetite disorder | 22.27 | 9.88 | 62 | 238245 | 7677 | 79498404 |
Myoclonus | 22.26 | 9.88 | 30 | 238277 | 27630 | 79478451 |
Suicidal behaviour | 22.23 | 9.88 | 37 | 238270 | 3210 | 79502871 |
Aortic valve stenosis | 22.22 | 9.88 | 49 | 238258 | 5245 | 79500836 |
NPM1 gene mutation | 22.16 | 9.88 | 10 | 238297 | 130 | 79505951 |
Syncope | 22.10 | 9.88 | 390 | 237917 | 179059 | 79327022 |
Atrioventricular block complete | 22.07 | 9.88 | 11 | 238296 | 16599 | 79489482 |
Colitis ulcerative | 22.06 | 9.88 | 44 | 238263 | 34698 | 79471383 |
Hospitalisation | 22.02 | 9.88 | 400 | 237907 | 93836 | 79412245 |
Panniculitis | 21.97 | 9.88 | 5 | 238302 | 12366 | 79493715 |
Asthma exercise induced | 21.96 | 9.88 | 10 | 238297 | 133 | 79505948 |
Functional residual capacity increased | 21.86 | 9.88 | 9 | 238298 | 92 | 79505989 |
Homicidal ideation | 21.83 | 9.88 | 38 | 238269 | 3419 | 79502662 |
Obsessive-compulsive disorder | 21.72 | 9.88 | 52 | 238255 | 5875 | 79500206 |
Upper airway obstruction | 21.72 | 9.88 | 24 | 238283 | 1404 | 79504677 |
Ligament pain | 21.71 | 9.88 | 12 | 238295 | 246 | 79505835 |
Joint stiffness | 21.64 | 9.88 | 57 | 238250 | 40773 | 79465308 |
Overweight | 21.64 | 9.88 | 42 | 238265 | 4108 | 79501973 |
Dysphemia | 21.61 | 9.88 | 38 | 238269 | 3446 | 79502635 |
Subdural haematoma | 21.55 | 9.88 | 38 | 238269 | 31396 | 79474685 |
Pathogen resistance | 21.43 | 9.88 | 8 | 238299 | 14334 | 79491747 |
Hyposmia | 21.43 | 9.88 | 18 | 238289 | 747 | 79505334 |
Endocarditis fibroplastica | 21.42 | 9.88 | 6 | 238301 | 15 | 79506066 |
Myelodysplastic syndrome | 21.35 | 9.88 | 36 | 238271 | 30265 | 79475816 |
Nasal turbinate abnormality | 21.27 | 9.88 | 7 | 238300 | 35 | 79506046 |
Injection site swelling | 21.26 | 9.88 | 225 | 238082 | 46907 | 79459174 |
Cytomegalovirus viraemia | 21.19 | 9.88 | 6 | 238301 | 12815 | 79493266 |
Exposure to allergen | 21.12 | 9.88 | 13 | 238294 | 328 | 79505753 |
Onychophagia | 21.12 | 9.88 | 9 | 238298 | 101 | 79505980 |
Injection site urticaria | 21.03 | 9.88 | 85 | 238222 | 12741 | 79493340 |
Type 2 diabetes mellitus | 20.97 | 9.88 | 262 | 238045 | 56860 | 79449221 |
Choking sensation | 20.94 | 9.88 | 40 | 238267 | 3866 | 79502215 |
Blood phosphorus increased | 20.92 | 9.88 | 3 | 238304 | 10344 | 79495737 |
Cortisol decreased | 20.90 | 9.88 | 29 | 238278 | 2143 | 79503938 |
Intervertebral disc degeneration | 20.83 | 9.88 | 98 | 238209 | 15687 | 79490394 |
CFTR gene mutation | 20.81 | 9.88 | 9 | 238298 | 105 | 79505976 |
Ear swelling | 20.75 | 9.88 | 25 | 238282 | 1606 | 79504475 |
Cold urticaria | 20.58 | 9.88 | 9 | 238298 | 108 | 79505973 |
Mental disorder | 20.52 | 9.88 | 162 | 238145 | 31140 | 79474941 |
Ligament sprain | 20.33 | 9.88 | 87 | 238220 | 13377 | 79492704 |
Toxic skin eruption | 20.25 | 9.88 | 22 | 238285 | 22271 | 79483810 |
Hiatus hernia | 20.15 | 9.88 | 129 | 238178 | 23183 | 79482898 |
Poisoning deliberate | 20.15 | 9.88 | 16 | 238291 | 18812 | 79487269 |
Palpitations | 20.07 | 9.88 | 508 | 237799 | 126102 | 79379979 |
Electrocardiogram QRS complex prolonged | 20.01 | 9.88 | 4 | 238303 | 10829 | 79495252 |
Nasal discomfort | 19.98 | 9.88 | 48 | 238259 | 5435 | 79500646 |
Glomerular filtration rate decreased | 19.97 | 9.88 | 23 | 238284 | 22679 | 79483402 |
Oliguria | 19.92 | 9.88 | 12 | 238295 | 16297 | 79489784 |
Pulmonary renal syndrome | 19.90 | 9.88 | 16 | 238291 | 624 | 79505457 |
Prothrombin time prolonged | 19.86 | 9.88 | 13 | 238294 | 16886 | 79489195 |
Blood lactate dehydrogenase increased | 19.77 | 9.88 | 56 | 238251 | 39114 | 79466967 |
Intestinal perforation | 19.69 | 9.88 | 14 | 238293 | 17412 | 79488669 |
Acidosis | 19.67 | 9.88 | 18 | 238289 | 19744 | 79486337 |
Ocular discomfort | 19.66 | 9.88 | 45 | 238262 | 4938 | 79501143 |
Blood immunoglobulin G decreased | 19.63 | 9.88 | 36 | 238271 | 3373 | 79502708 |
Lung opacity | 19.62 | 9.88 | 46 | 238261 | 5128 | 79500953 |
Toxic encephalopathy | 19.58 | 9.88 | 5 | 238302 | 11435 | 79494646 |
Nasal septum deviation | 19.53 | 9.88 | 26 | 238281 | 1847 | 79504234 |
Sputum retention | 19.45 | 9.88 | 20 | 238287 | 1077 | 79505004 |
Weight increased | 19.34 | 9.88 | 1014 | 237293 | 276372 | 79229709 |
Lactose intolerance | 19.34 | 9.88 | 29 | 238278 | 2301 | 79503780 |
Injection site movement impairment | 19.31 | 9.88 | 6 | 238301 | 24 | 79506057 |
Sinus polyp degeneration | 19.30 | 9.88 | 7 | 238300 | 49 | 79506032 |
Encephalitis | 19.27 | 9.88 | 10 | 238297 | 14750 | 79491331 |
Muscular weakness | 19.26 | 9.88 | 351 | 237956 | 160378 | 79345703 |
Nocturnal dyspnoea | 19.19 | 9.88 | 24 | 238283 | 1602 | 79504479 |
Basal cell carcinoma | 19.19 | 9.88 | 53 | 238254 | 37322 | 79468759 |
Shock haemorrhagic | 19.12 | 9.88 | 19 | 238288 | 20041 | 79486040 |
Pigment dispersion syndrome | 18.93 | 9.88 | 6 | 238301 | 26 | 79506055 |
Adrenal suppression | 18.71 | 9.88 | 22 | 238285 | 1377 | 79504704 |
Oesophageal carcinoma | 18.67 | 9.88 | 5 | 238302 | 11079 | 79495002 |
Shock | 18.67 | 9.88 | 67 | 238240 | 43481 | 79462600 |
Pulmonary oedema | 18.66 | 9.88 | 171 | 238136 | 88083 | 79417998 |
Blood potassium increased | 18.65 | 9.88 | 37 | 238270 | 29238 | 79476843 |
Muscle spasticity | 18.63 | 9.88 | 22 | 238285 | 21453 | 79484628 |
Ankle fracture | 18.62 | 9.88 | 100 | 238207 | 16869 | 79489212 |
Klebsiella infection | 18.60 | 9.88 | 12 | 238295 | 15708 | 79490373 |
Ileus | 18.60 | 9.88 | 31 | 238276 | 26180 | 79479901 |
Airway peak pressure increased | 18.45 | 9.88 | 12 | 238295 | 334 | 79505747 |
Child abuse | 18.40 | 9.88 | 13 | 238294 | 416 | 79505665 |
Benign prostatic hyperplasia | 18.29 | 9.88 | 76 | 238231 | 11536 | 79494545 |
Splenomegaly | 18.28 | 9.88 | 21 | 238286 | 20733 | 79485348 |
Ventricular fibrillation | 18.14 | 9.88 | 43 | 238264 | 31883 | 79474198 |
Allergy test positive | 18.10 | 9.88 | 16 | 238291 | 712 | 79505369 |
Infusion site pain | 17.98 | 9.88 | 87 | 238220 | 14089 | 79491992 |
Blood calcium decreased | 17.97 | 9.88 | 43 | 238264 | 31776 | 79474305 |
Increased upper airway secretion | 17.91 | 9.88 | 39 | 238268 | 4138 | 79501943 |
Lung hernia | 17.88 | 9.88 | 7 | 238300 | 62 | 79506019 |
Inappropriate antidiuretic hormone secretion | 17.87 | 9.88 | 32 | 238275 | 26281 | 79479800 |
Proctalgia | 17.84 | 9.88 | 4 | 238303 | 9997 | 79496084 |
Injection site rash | 17.83 | 9.88 | 103 | 238204 | 17851 | 79488230 |
Brain oedema | 17.81 | 9.88 | 30 | 238277 | 25233 | 79480848 |
Diaphragmatic disorder | 17.80 | 9.88 | 24 | 238283 | 1726 | 79504355 |
Injection site hypoaesthesia | 17.77 | 9.88 | 14 | 238293 | 530 | 79505551 |
Sleep talking | 17.68 | 9.88 | 19 | 238288 | 1077 | 79505004 |
Hepatic cirrhosis | 17.55 | 9.88 | 50 | 238257 | 34856 | 79471225 |
Blood lactic acid | 17.51 | 9.88 | 13 | 238294 | 450 | 79505631 |
Ataxia | 17.41 | 9.88 | 30 | 238277 | 25009 | 79481072 |
Atrial fibrillation | 17.40 | 9.88 | 454 | 237853 | 197432 | 79308649 |
Product dose omission in error | 17.33 | 9.88 | 57 | 238250 | 7731 | 79498350 |
Drug eruption | 17.28 | 9.88 | 70 | 238237 | 43865 | 79462216 |
Respiratory failure | 17.27 | 9.88 | 410 | 237897 | 180501 | 79325580 |
Mycotic allergy | 17.26 | 9.88 | 22 | 238285 | 1497 | 79504584 |
Hepatitis C | 17.25 | 9.88 | 7 | 238300 | 11918 | 79494163 |
Pulmonary artery stenosis congenital | 17.19 | 9.88 | 5 | 238302 | 15 | 79506066 |
Meningitis eosinophilic | 17.19 | 9.88 | 5 | 238302 | 15 | 79506066 |
Muscle tension dysphonia | 17.18 | 9.88 | 9 | 238298 | 165 | 79505916 |
Renal disorder | 17.15 | 9.88 | 197 | 238110 | 41908 | 79464173 |
Haemophilus infection | 17.03 | 9.88 | 27 | 238280 | 2249 | 79503832 |
Aplastic anaemia | 17.02 | 9.88 | 17 | 238290 | 17888 | 79488193 |
Hyperkaliuria | 16.99 | 9.88 | 9 | 238298 | 169 | 79505912 |
Ileus paralytic | 16.86 | 9.88 | 4 | 238303 | 9616 | 79496465 |
Tachypnoea | 16.81 | 9.88 | 45 | 238262 | 32018 | 79474063 |
Speech disorder | 16.79 | 9.88 | 242 | 238065 | 54203 | 79451878 |
Infusion site bruising | 16.78 | 9.88 | 31 | 238276 | 2921 | 79503160 |
Chest pain | 16.77 | 9.88 | 1017 | 237290 | 281287 | 79224794 |
Catatonia | 16.67 | 9.88 | 3 | 238304 | 8753 | 79497328 |
Prostatomegaly | 16.66 | 9.88 | 34 | 238273 | 3449 | 79502632 |
Pharyngeal oedema | 16.59 | 9.88 | 94 | 238213 | 16178 | 79489903 |
Hepatitis | 16.58 | 9.88 | 98 | 238209 | 55629 | 79450452 |
Vasomotor rhinitis | 16.53 | 9.88 | 9 | 238298 | 179 | 79505902 |
Infection | 16.44 | 9.88 | 574 | 237733 | 241138 | 79264943 |
Drug use disorder | 16.39 | 9.88 | 3 | 238304 | 8648 | 79497433 |
Drug ineffective for unapproved indication | 16.39 | 9.88 | 88 | 238219 | 51150 | 79454931 |
Hallucination | 16.35 | 9.88 | 353 | 237954 | 85392 | 79420689 |
Ejection fraction decreased | 16.32 | 9.88 | 51 | 238256 | 34526 | 79471555 |
Gluten sensitivity | 16.27 | 9.88 | 12 | 238295 | 411 | 79505670 |
Hypertensive crisis | 16.24 | 9.88 | 23 | 238284 | 20747 | 79485334 |
Pregnancy | 16.21 | 9.88 | 35 | 238272 | 26816 | 79479265 |
Decreased activity | 16.20 | 9.88 | 60 | 238247 | 8634 | 79497447 |
Abdominal pain | 16.18 | 9.88 | 976 | 237331 | 388593 | 79117488 |
Arthralgia | 16.16 | 9.88 | 1480 | 236827 | 570323 | 78935758 |
Panic reaction | 16.11 | 9.88 | 40 | 238267 | 4625 | 79501456 |
Hypercapnia | 16.10 | 9.88 | 61 | 238246 | 8874 | 79497207 |
Bronchitis chronic | 16.08 | 9.88 | 39 | 238268 | 4443 | 79501638 |
Fall | 16.04 | 9.88 | 1247 | 237060 | 486382 | 79019699 |
Dialysis | 15.92 | 9.88 | 19 | 238288 | 18443 | 79487638 |
Enterococcal infection | 15.91 | 9.88 | 14 | 238293 | 15646 | 79490435 |
Bladder cancer | 15.89 | 9.88 | 21 | 238286 | 19505 | 79486576 |
Vocal cord disorder | 15.85 | 9.88 | 21 | 238286 | 1485 | 79504596 |
Gastric haemorrhage | 15.84 | 9.88 | 13 | 238294 | 15037 | 79491044 |
Hemiparesis | 15.75 | 9.88 | 50 | 238257 | 33683 | 79472398 |
Eosinophil count abnormal | 15.74 | 9.88 | 15 | 238292 | 736 | 79505345 |
Allergic sinusitis | 15.72 | 9.88 | 16 | 238291 | 851 | 79505230 |
Product taste abnormal | 15.71 | 9.88 | 26 | 238281 | 2245 | 79503836 |
Foot deformity | 15.71 | 9.88 | 30 | 238277 | 24044 | 79482037 |
Abdominal pain lower | 15.63 | 9.88 | 46 | 238261 | 31736 | 79474345 |
Urosepsis | 15.61 | 9.88 | 35 | 238272 | 26460 | 79479621 |
Femur fracture | 15.57 | 9.88 | 61 | 238246 | 38591 | 79467490 |
Muscle rigidity | 15.56 | 9.88 | 22 | 238285 | 19860 | 79486221 |
Blood parathyroid hormone decreased | 15.54 | 9.88 | 6 | 238301 | 10530 | 79495551 |
Premature delivery | 15.52 | 9.88 | 29 | 238278 | 23438 | 79482643 |
Hypothyroidism | 15.42 | 9.88 | 231 | 238076 | 52161 | 79453920 |
Peripheral sensory neuropathy | 15.35 | 9.88 | 10 | 238297 | 13023 | 79493058 |
Acute pulmonary oedema | 15.35 | 9.88 | 12 | 238295 | 14218 | 79491863 |
Steroid diabetes | 15.34 | 9.88 | 33 | 238274 | 3473 | 79502608 |
Injection site erythema | 15.25 | 9.88 | 323 | 237984 | 77874 | 79428207 |
Gangrene | 15.18 | 9.88 | 4 | 238303 | 8960 | 79497121 |
Hypothermia | 15.14 | 9.88 | 28 | 238279 | 22718 | 79483363 |
Haematocrit decreased | 15.14 | 9.88 | 114 | 238193 | 61198 | 79444883 |
Chimerism | 15.14 | 9.88 | 10 | 238297 | 286 | 79505795 |
Seizure | 15.11 | 9.88 | 439 | 237868 | 188395 | 79317686 |
Hypohidrosis | 15.11 | 9.88 | 10 | 238297 | 287 | 79505794 |
Breast conserving surgery | 15.10 | 9.88 | 15 | 238292 | 775 | 79505306 |
Musculoskeletal pain | 15.10 | 9.88 | 215 | 238092 | 102139 | 79403942 |
Obesity | 15.06 | 9.88 | 166 | 238141 | 34959 | 79471122 |
Spinal operation | 15.06 | 9.88 | 55 | 238252 | 7862 | 79498219 |
Dizziness exertional | 15.05 | 9.88 | 13 | 238294 | 561 | 79505520 |
Duodenal ulcer | 15.04 | 9.88 | 16 | 238291 | 16353 | 79489728 |
Sputum culture | 14.98 | 9.88 | 9 | 238298 | 217 | 79505864 |
Skin lesion | 14.96 | 9.88 | 191 | 238116 | 41653 | 79464428 |
Pulmonary thrombosis | 14.94 | 9.88 | 74 | 238233 | 12097 | 79493984 |
Mucosal discolouration | 14.89 | 9.88 | 15 | 238292 | 788 | 79505293 |
Product availability issue | 14.86 | 9.88 | 35 | 238272 | 3912 | 79502169 |
Body temperature abnormal | 14.86 | 9.88 | 26 | 238281 | 2349 | 79503732 |
Kidney transplant rejection | 14.84 | 9.88 | 6 | 238301 | 10240 | 79495841 |
Eye paraesthesia | 14.83 | 9.88 | 8 | 238299 | 156 | 79505925 |
Breast neoplasm | 14.76 | 9.88 | 16 | 238291 | 916 | 79505165 |
Sedation complication | 14.75 | 9.88 | 15 | 238292 | 15654 | 79490427 |
Gastric cancer | 14.68 | 9.88 | 6 | 238301 | 10173 | 79495908 |
Delusion | 14.63 | 9.88 | 24 | 238283 | 20399 | 79485682 |
Therapeutic response unexpected | 14.63 | 9.88 | 106 | 238201 | 19840 | 79486241 |
Hallucination, auditory | 14.63 | 9.88 | 109 | 238198 | 20584 | 79485497 |
Tumour lysis syndrome | 14.62 | 9.88 | 31 | 238276 | 23908 | 79482173 |
Hypernatraemia | 14.58 | 9.88 | 13 | 238294 | 14438 | 79491643 |
Body mass index increased | 14.56 | 9.88 | 23 | 238284 | 1910 | 79504171 |
Leukoencephalopathy | 14.50 | 9.88 | 3 | 238304 | 7926 | 79498155 |
Skin swelling | 14.48 | 9.88 | 35 | 238272 | 3979 | 79502102 |
Osteomyelitis | 14.46 | 9.88 | 50 | 238257 | 32815 | 79473266 |
Pigmentary glaucoma | 14.45 | 9.88 | 3 | 238304 | 0 | 79506081 |
Sleep study abnormal | 14.45 | 9.88 | 3 | 238304 | 0 | 79506081 |
Hypovolaemia | 14.43 | 9.88 | 19 | 238288 | 17672 | 79488409 |
Gastroenteritis viral | 14.40 | 9.88 | 125 | 238182 | 24706 | 79481375 |
Psoriasis | 14.36 | 9.88 | 360 | 237947 | 89227 | 79416854 |
Bronchopulmonary aspergillosis | 14.36 | 9.88 | 28 | 238279 | 22266 | 79483815 |
Urinary tract infection | 14.35 | 9.88 | 672 | 237635 | 273840 | 79232241 |
Pyrexia | 14.32 | 9.88 | 1793 | 236514 | 676916 | 78829165 |
Blood albumin decreased | 14.30 | 9.88 | 32 | 238275 | 24211 | 79481870 |
Oral pruritus | 14.29 | 9.88 | 26 | 238281 | 2422 | 79503659 |
Peak expiratory flow rate increased | 14.28 | 9.88 | 4 | 238303 | 10 | 79506071 |
Oxygen saturation decreased | 14.24 | 9.88 | 495 | 237812 | 128552 | 79377529 |
Dermatitis acneiform | 14.24 | 9.88 | 6 | 238301 | 9987 | 79496094 |
Cardiac tamponade | 14.16 | 9.88 | 5 | 238302 | 9271 | 79496810 |
Mouth swelling | 14.11 | 9.88 | 45 | 238262 | 6006 | 79500075 |
Endocarditis | 14.10 | 9.88 | 7 | 238300 | 10590 | 79495491 |
Paternal exposure during pregnancy | 14.03 | 9.88 | 6 | 238301 | 68 | 79506013 |
School refusal | 13.91 | 9.88 | 5 | 238302 | 34 | 79506047 |
Bronchiolitis obliterans syndrome | 13.91 | 9.88 | 10 | 238297 | 329 | 79505752 |
Obsessive thoughts | 13.83 | 9.88 | 17 | 238290 | 1115 | 79504966 |
Hypervolaemia | 13.83 | 9.88 | 73 | 238234 | 42617 | 79463464 |
Uveitis | 13.80 | 9.88 | 18 | 238289 | 16812 | 79489269 |
Allergic respiratory disease | 13.78 | 9.88 | 7 | 238300 | 120 | 79505961 |
Adenotonsillectomy | 13.72 | 9.88 | 6 | 238301 | 72 | 79506009 |
Conjunctivitis allergic | 13.70 | 9.88 | 21 | 238286 | 1699 | 79504382 |
Pneumonia viral | 13.69 | 9.88 | 59 | 238248 | 9099 | 79496982 |
Grip strength decreased | 13.62 | 9.88 | 28 | 238279 | 21841 | 79484240 |
Cystic fibrosis respiratory infection suppression | 13.59 | 9.88 | 11 | 238296 | 433 | 79505648 |
Nodular vasculitis | 13.55 | 9.88 | 5 | 238302 | 37 | 79506044 |
Bone density decreased | 13.54 | 9.88 | 77 | 238230 | 13270 | 79492811 |
Incorrect route of product administration | 13.52 | 9.88 | 56 | 238251 | 34873 | 79471208 |
Laryngospasm | 13.51 | 9.88 | 34 | 238273 | 3963 | 79502118 |
Bronchiolitis | 13.51 | 9.88 | 35 | 238272 | 4153 | 79501928 |
Injection site eczema | 13.50 | 9.88 | 6 | 238301 | 75 | 79506006 |
Blood uric acid increased | 13.50 | 9.88 | 12 | 238295 | 13348 | 79492733 |
Otorrhoea | 13.47 | 9.88 | 21 | 238286 | 1724 | 79504357 |
Faecaloma | 13.45 | 9.88 | 9 | 238298 | 11555 | 79494526 |
Depressive symptom | 13.40 | 9.88 | 46 | 238261 | 6377 | 79499704 |
Epstein-Barr virus infection | 13.35 | 9.88 | 14 | 238293 | 14402 | 79491679 |
Drug level decreased | 13.32 | 9.88 | 14 | 238293 | 14388 | 79491693 |
Concussion | 13.28 | 9.88 | 60 | 238247 | 9443 | 79496638 |
Nasal pruritus | 13.28 | 9.88 | 12 | 238295 | 550 | 79505531 |
Device related infection | 13.26 | 9.88 | 55 | 238252 | 34239 | 79471842 |
Oral mucosal blistering | 13.25 | 9.88 | 45 | 238262 | 6206 | 79499875 |
Vaccination site pain | 13.20 | 9.88 | 8 | 238299 | 196 | 79505885 |
Mental status changes | 13.20 | 9.88 | 132 | 238175 | 66827 | 79439254 |
Abdominal distension | 13.19 | 9.88 | 265 | 238042 | 119385 | 79386696 |
Granulocytopenia | 13.16 | 9.88 | 9 | 238298 | 11422 | 79494659 |
Upper respiratory tract congestion | 13.15 | 9.88 | 26 | 238281 | 2577 | 79503504 |
Pneumonia mycoplasmal | 13.14 | 9.88 | 19 | 238288 | 1459 | 79504622 |
Functional residual capacity decreased | 13.09 | 9.88 | 6 | 238301 | 81 | 79506000 |
BK virus infection | 13.01 | 9.88 | 5 | 238302 | 8799 | 79497282 |
Vaccination site swelling | 13.00 | 9.88 | 5 | 238302 | 42 | 79506039 |
Respiratory fume inhalation disorder | 12.99 | 9.88 | 8 | 238299 | 202 | 79505879 |
Sinus headache | 12.98 | 9.88 | 39 | 238268 | 5041 | 79501040 |
Fatigue | 12.93 | 9.88 | 3049 | 235258 | 926678 | 78579403 |
Respiratory syncytial virus infection | 12.87 | 9.88 | 59 | 238248 | 9343 | 79496738 |
Febrile convulsion | 12.86 | 9.88 | 15 | 238292 | 931 | 79505150 |
Insurance issue | 12.80 | 9.88 | 42 | 238265 | 5691 | 79500390 |
Cytomegalovirus infection reactivation | 12.80 | 9.88 | 5 | 238302 | 8711 | 79497370 |
Bradyphrenia | 12.76 | 9.88 | 8 | 238299 | 10632 | 79495449 |
Anaphylactic shock | 12.74 | 9.88 | 164 | 238143 | 35832 | 79470249 |
Expiratory reserve volume decreased | 12.71 | 9.88 | 6 | 238301 | 87 | 79505994 |
Pneumococcal infection | 12.71 | 9.88 | 15 | 238292 | 943 | 79505138 |
Alice in wonderland syndrome | 12.70 | 9.88 | 5 | 238302 | 45 | 79506036 |
Lymphostasis | 12.68 | 9.88 | 4 | 238303 | 17 | 79506064 |
Duodenitis | 12.67 | 9.88 | 4 | 238303 | 7963 | 79498118 |
Eosinophilic pneumonia acute | 12.63 | 9.88 | 16 | 238291 | 1082 | 79504999 |
Colorectal cancer | 12.63 | 9.88 | 5 | 238302 | 8642 | 79497439 |
Suspected suicide | 12.62 | 9.88 | 8 | 238299 | 10568 | 79495513 |
Epilepsy | 12.61 | 9.88 | 71 | 238236 | 40789 | 79465292 |
Blood pressure systolic abnormal | 12.61 | 9.88 | 20 | 238287 | 17227 | 79488854 |
Product appearance confusion | 12.61 | 9.88 | 5 | 238302 | 46 | 79506035 |
Enteritis | 12.58 | 9.88 | 15 | 238292 | 14568 | 79491513 |
Mandibular mass | 12.58 | 9.88 | 8 | 238299 | 214 | 79505867 |
Troponin increased | 12.56 | 9.88 | 24 | 238283 | 19231 | 79486850 |
Acute sinusitis | 12.55 | 9.88 | 36 | 238271 | 4534 | 79501547 |
Gastroenteritis eosinophilic | 12.52 | 9.88 | 9 | 238298 | 296 | 79505785 |
Pulmonary congestion | 12.52 | 9.88 | 130 | 238177 | 26970 | 79479111 |
Cephalo-pelvic disproportion | 12.51 | 9.88 | 7 | 238300 | 147 | 79505934 |
Hepatic cancer | 12.51 | 9.88 | 8 | 238299 | 10521 | 79495560 |
Eye irritation | 12.46 | 9.88 | 105 | 238202 | 20576 | 79485505 |
Respiratory gas exchange disorder | 12.42 | 9.88 | 14 | 238293 | 837 | 79505244 |
Hyperammonaemia | 12.42 | 9.88 | 9 | 238298 | 11084 | 79494997 |
Myositis | 12.41 | 9.88 | 24 | 238283 | 19144 | 79486937 |
Choking | 12.40 | 9.88 | 70 | 238237 | 12031 | 79494050 |
Cachexia | 12.40 | 9.88 | 9 | 238298 | 11074 | 79495007 |
Psychological trauma | 12.39 | 9.88 | 18 | 238289 | 1388 | 79504693 |
Cushingoid | 12.38 | 9.88 | 59 | 238248 | 9493 | 79496588 |
Platelet adhesiveness decreased | 12.38 | 9.88 | 3 | 238304 | 3 | 79506078 |
Chronic rhinosinusitis with nasal polyps | 12.38 | 9.88 | 3 | 238304 | 3 | 79506078 |
Fight in school | 12.38 | 9.88 | 3 | 238304 | 3 | 79506078 |
Upper airway resistance syndrome | 12.38 | 9.88 | 3 | 238304 | 3 | 79506078 |
Allergy to fermented products | 12.38 | 9.88 | 3 | 238304 | 3 | 79506078 |
Serum ferritin increased | 12.38 | 9.88 | 7 | 238300 | 9840 | 79496241 |
Periorbital swelling | 12.38 | 9.88 | 27 | 238280 | 2869 | 79503212 |
Abortion | 12.35 | 9.88 | 18 | 238289 | 1392 | 79504689 |
Ventricular tachycardia | 12.34 | 9.88 | 74 | 238233 | 41861 | 79464220 |
Cold agglutinins positive | 12.33 | 9.88 | 5 | 238302 | 49 | 79506032 |
Autophobia | 12.32 | 9.88 | 4 | 238303 | 19 | 79506062 |
Malnutrition | 12.24 | 9.88 | 31 | 238276 | 22471 | 79483610 |
Drug ineffective | 12.23 | 9.88 | 2955 | 235352 | 1077958 | 78428123 |
Lupus-like syndrome | 12.23 | 9.88 | 14 | 238293 | 13843 | 79492238 |
Drug level below therapeutic | 12.20 | 9.88 | 7 | 238300 | 9763 | 79496318 |
Mycobacterial infection | 12.19 | 9.88 | 31 | 238276 | 3637 | 79502444 |
Self esteem decreased | 12.16 | 9.88 | 15 | 238292 | 987 | 79505094 |
Ear pain | 12.16 | 9.88 | 151 | 238156 | 32718 | 79473363 |
Systemic infection | 12.16 | 9.88 | 7 | 238300 | 9745 | 79496336 |
Cronobacter infection | 12.16 | 9.88 | 4 | 238303 | 20 | 79506061 |
Akathisia | 12.14 | 9.88 | 13 | 238294 | 13246 | 79492835 |
Gastric ulcer | 12.12 | 9.88 | 56 | 238251 | 33849 | 79472232 |
Stiff person syndrome | 12.08 | 9.88 | 9 | 238298 | 313 | 79505768 |
Diverticulum oesophageal | 12.06 | 9.88 | 7 | 238300 | 158 | 79505923 |
Infusion site mass | 12.06 | 9.88 | 19 | 238288 | 1574 | 79504507 |
Unintentional medical device removal | 12.04 | 9.88 | 4 | 238303 | 7708 | 79498373 |
Renal injury | 12.03 | 9.88 | 20 | 238287 | 16907 | 79489174 |
Autism spectrum disorder | 12.03 | 9.88 | 16 | 238291 | 1136 | 79504945 |
Hyperreflexia | 12 | 9.88 | 5 | 238302 | 8380 | 79497701 |
Breast cancer | 11.99 | 9.88 | 154 | 238153 | 33627 | 79472454 |
Neuritis | 11.99 | 9.88 | 20 | 238287 | 1738 | 79504343 |
Allergy to plants | 11.97 | 9.88 | 13 | 238294 | 746 | 79505335 |
Therapy partial responder | 11.95 | 9.88 | 21 | 238286 | 17376 | 79488705 |
Systemic inflammatory response syndrome | 11.95 | 9.88 | 10 | 238297 | 11455 | 79494626 |
Transaminases increased | 11.94 | 9.88 | 98 | 238209 | 51645 | 79454436 |
Red blood cell count decreased | 11.92 | 9.88 | 112 | 238195 | 57401 | 79448680 |
Polyneuropathy | 11.85 | 9.88 | 35 | 238272 | 24116 | 79481965 |
Sinonasal obstruction | 11.84 | 9.88 | 9 | 238298 | 323 | 79505758 |
Oesophagogastroduodenoscopy | 11.80 | 9.88 | 8 | 238299 | 239 | 79505842 |
Injection site bruising | 11.77 | 9.88 | 180 | 238127 | 40822 | 79465259 |
Head banging | 11.71 | 9.88 | 11 | 238296 | 530 | 79505551 |
Abnormal weight gain | 11.70 | 9.88 | 25 | 238282 | 2619 | 79503462 |
Graft versus host disease in lung | 11.64 | 9.88 | 14 | 238293 | 898 | 79505183 |
Myalgia | 11.63 | 9.88 | 672 | 237635 | 184969 | 79321112 |
Acute coronary syndrome | 11.59 | 9.88 | 29 | 238278 | 21104 | 79484977 |
Distal intestinal obstruction syndrome | 11.58 | 9.88 | 13 | 238294 | 774 | 79505307 |
Bacterial sepsis | 11.55 | 9.88 | 5 | 238302 | 8193 | 79497888 |
Blood immunoglobulin E decreased | 11.55 | 9.88 | 6 | 238301 | 108 | 79505973 |
Ventricular arrhythmia | 11.53 | 9.88 | 6 | 238301 | 8834 | 79497247 |
Dyskinesia oesophageal | 11.51 | 9.88 | 5 | 238302 | 59 | 79506022 |
Lower gastrointestinal haemorrhage | 11.51 | 9.88 | 19 | 238288 | 16106 | 79489975 |
Embolism | 11.42 | 9.88 | 15 | 238292 | 13967 | 79492114 |
Defiant behaviour | 11.42 | 9.88 | 4 | 238303 | 25 | 79506056 |
Enterocolitis | 11.42 | 9.88 | 16 | 238291 | 14496 | 79491585 |
Constipation | 11.41 | 9.88 | 711 | 237596 | 282339 | 79223742 |
Flushing | 11.40 | 9.88 | 345 | 237962 | 87923 | 79418158 |
Formication | 11.39 | 9.88 | 37 | 238270 | 4986 | 79501095 |
Venoocclusive liver disease | 11.39 | 9.88 | 11 | 238296 | 11760 | 79494321 |
Systemic candida | 11.34 | 9.88 | 3 | 238304 | 6703 | 79499378 |
Hypovolaemic shock | 11.28 | 9.88 | 12 | 238295 | 12264 | 79493817 |
Anal abscess | 11.26 | 9.88 | 7 | 238300 | 9348 | 79496733 |
Paranasal sinus discomfort | 11.19 | 9.88 | 34 | 238273 | 4422 | 79501659 |
Cholangitis | 11.18 | 9.88 | 13 | 238294 | 12763 | 79493318 |
Cough variant asthma | 11.17 | 9.88 | 3 | 238304 | 6 | 79506075 |
Hyperventilation | 11.13 | 9.88 | 50 | 238257 | 7849 | 79498232 |
Atrioventricular block second degree | 11.06 | 9.88 | 4 | 238303 | 7308 | 79498773 |
Viral myelitis | 11.03 | 9.88 | 6 | 238301 | 119 | 79505962 |
Small airways disease | 11.03 | 9.88 | 4 | 238303 | 28 | 79506053 |
COVID-19 immunisation | 11.03 | 9.88 | 17 | 238290 | 1382 | 79504699 |
Crepitations | 10.97 | 9.88 | 59 | 238248 | 9958 | 79496123 |
Lip discolouration | 10.94 | 9.88 | 12 | 238295 | 696 | 79505385 |
Female genital tract fistula | 10.94 | 9.88 | 41 | 238266 | 5934 | 79500147 |
Metastases to lymph nodes | 10.92 | 9.88 | 9 | 238298 | 10388 | 79495693 |
Drug withdrawal syndrome | 10.90 | 9.88 | 60 | 238247 | 34658 | 79471423 |
Dry skin | 10.82 | 9.88 | 273 | 238034 | 67722 | 79438359 |
Exposure to toxic agent | 10.82 | 9.88 | 7 | 238300 | 9151 | 79496930 |
Blood immunoglobulin E abnormal | 10.79 | 9.88 | 4 | 238303 | 30 | 79506051 |
Peripheral swelling | 10.74 | 9.88 | 678 | 237629 | 268939 | 79237142 |
Blood lactic acid increased | 10.70 | 9.88 | 70 | 238237 | 12674 | 79493407 |
Blood creatinine decreased | 10.67 | 9.88 | 5 | 238302 | 7820 | 79498261 |
Vascular device infection | 10.66 | 9.88 | 9 | 238298 | 10267 | 79495814 |
Pulmonary arterial hypertension | 10.65 | 9.88 | 46 | 238261 | 28320 | 79477761 |
Heparin-induced thrombocytopenia | 10.65 | 9.88 | 8 | 238299 | 9674 | 79496407 |
Violence-related symptom | 10.63 | 9.88 | 12 | 238295 | 719 | 79505362 |
Gout | 10.63 | 9.88 | 117 | 238190 | 24632 | 79481449 |
Diabetes mellitus inadequate control | 10.62 | 9.88 | 37 | 238270 | 24227 | 79481854 |
Product container issue | 10.62 | 9.88 | 16 | 238291 | 1275 | 79504806 |
Eyelid infection | 10.58 | 9.88 | 9 | 238298 | 380 | 79505701 |
Aphasia | 10.56 | 9.88 | 89 | 238218 | 46643 | 79459438 |
Fracture pain | 10.56 | 9.88 | 12 | 238295 | 724 | 79505357 |
Photosensitivity reaction | 10.55 | 9.88 | 103 | 238204 | 21024 | 79485057 |
Blood calcium increased | 10.55 | 9.88 | 60 | 238247 | 10340 | 79495741 |
Growth retardation | 10.54 | 9.88 | 20 | 238287 | 1923 | 79504158 |
Oral herpes | 10.54 | 9.88 | 127 | 238180 | 27327 | 79478754 |
Immunosuppressant drug level increased | 10.53 | 9.88 | 7 | 238300 | 9020 | 79497061 |
Dystonia | 10.50 | 9.88 | 31 | 238276 | 21368 | 79484713 |
Adjustment disorder | 10.50 | 9.88 | 31 | 238276 | 3969 | 79502112 |
Colitis microscopic | 10.49 | 9.88 | 10 | 238297 | 10758 | 79495323 |
Occupational exposure to dust | 10.46 | 9.88 | 4 | 238303 | 33 | 79506048 |
Pertussis | 10.46 | 9.88 | 13 | 238294 | 862 | 79505219 |
Pulmonary toxicity | 10.40 | 9.88 | 14 | 238293 | 12900 | 79493181 |
Animal scratch | 10.36 | 9.88 | 17 | 238290 | 1457 | 79504624 |
Hepatitis B | 10.36 | 9.88 | 6 | 238301 | 8326 | 79497755 |
Measles | 10.35 | 9.88 | 9 | 238298 | 392 | 79505689 |
Paraesthesia oral | 10.32 | 9.88 | 100 | 238207 | 20371 | 79485710 |
Blood immunoglobulin E | 10.32 | 9.88 | 3 | 238304 | 9 | 79506072 |
Hemiplegia | 10.30 | 9.88 | 18 | 238289 | 14921 | 79491160 |
Skin atrophy | 10.27 | 9.88 | 39 | 238268 | 5679 | 79500402 |
Bronchitis viral | 10.21 | 9.88 | 15 | 238292 | 1168 | 79504913 |
Hepatic cytolysis | 10.21 | 9.88 | 44 | 238263 | 27107 | 79478974 |
Hepatic lesion | 10.20 | 9.88 | 4 | 238303 | 6955 | 79499126 |
Administration site reaction | 10.20 | 9.88 | 6 | 238301 | 139 | 79505942 |
Laryngitis fungal | 10.16 | 9.88 | 6 | 238301 | 140 | 79505941 |
Benign renal neoplasm | 10.16 | 9.88 | 4 | 238303 | 36 | 79506045 |
Hyperplastic cholecystopathy | 10.13 | 9.88 | 7 | 238300 | 216 | 79505865 |
Bronchitis bacterial | 10.13 | 9.88 | 17 | 238290 | 1485 | 79504596 |
Enterobiasis | 10.07 | 9.88 | 4 | 238303 | 37 | 79506044 |
Ankylosing spondylitis | 10.06 | 9.88 | 13 | 238294 | 12192 | 79493889 |
PCO2 increased | 10.06 | 9.88 | 19 | 238288 | 1821 | 79504260 |
Retinal artery embolism | 10.05 | 9.88 | 6 | 238301 | 143 | 79505938 |
Infusion site extravasation | 10.05 | 9.88 | 58 | 238249 | 10050 | 79496031 |
Squamous cell carcinoma of the oral cavity | 10.04 | 9.88 | 10 | 238297 | 518 | 79505563 |
Alopecia areata | 10.04 | 9.88 | 19 | 238288 | 1824 | 79504257 |
Neurogenic shock | 10.02 | 9.88 | 11 | 238296 | 639 | 79505442 |
Hand fracture | 10.01 | 9.88 | 41 | 238266 | 6184 | 79499897 |
Euglycaemic diabetic ketoacidosis | 9.93 | 9.88 | 4 | 238303 | 6840 | 79499241 |
None
Source | Code | Description |
---|---|---|
ATC | R03DC03 | RESPIRATORY SYSTEM DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES Leukotriene receptor antagonists |
ATC | R03DC53 | RESPIRATORY SYSTEM DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES Leukotriene receptor antagonists |
FDA MoA | N0000000083 | Leukotriene Receptor Antagonists |
MeSH PA | D018927 | Anti-Asthmatic Agents |
MeSH PA | D065694 | Cytochrome P-450 CYP1A2 Inducers |
MeSH PA | D006727 | Hormone Antagonists |
MeSH PA | D020024 | Leukotriene Antagonists |
MeSH PA | D065606 | Metabolic Side Effects of Drugs and Substances |
MeSH PA | D019141 | Respiratory System Agents |
FDA EPC | N0000175777 | Leukotriene Receptor Antagonist |
CHEBI has role | CHEBI:38070 | antiarrhythmic agent |
CHEBI has role | CHEBI:49159 | leukotriene antagonists |
CHEBI has role | CHEBI:49167 | anti-asthmatic drugs |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Allergic rhinitis | indication | 61582004 | |
Non-allergic asthma | indication | 266361008 | DOID:9360 |
Allergic asthma | indication | 389145006 | DOID:9415 |
Asthma management | indication | 406162001 | |
Exercise-Induced Bronchospasm Prevention | indication | ||
Suicidal thoughts | contraindication | 6471006 | |
Hallucinations | contraindication | 7011001 | |
Mood swings | contraindication | 18963009 | |
Feeling agitated | contraindication | 24199005 | |
Depressive disorder | contraindication | 35489007 | |
Anxiety | contraindication | 48694002 | |
Vasculitis of the skin | contraindication | 53312001 | |
Dream disorder | contraindication | 85418005 | |
Eosinophil count raised | contraindication | 386789004 | |
Tremors | contraindication | ||
Nervousness | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 4.28 | acidic |
pKa2 | 4.98 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Cysteinyl leukotriene receptor 1 | GPCR | ANTAGONIST | Ki | 9.30 | CHEMBL | CHEMBL | |||
Alpha-2A adrenergic receptor | GPCR | Ki | 5.83 | DRUG MATRIX | |||||
Sodium-dependent noradrenaline transporter | Transporter | Ki | 5.57 | DRUG MATRIX | |||||
5-hydroxytryptamine receptor 2B | GPCR | Ki | 5.40 | DRUG MATRIX | |||||
D(3) dopamine receptor | GPCR | Ki | 5.58 | DRUG MATRIX | |||||
Muscarinic acetylcholine receptor M1 | GPCR | Ki | 5.71 | DRUG MATRIX | |||||
Muscarinic acetylcholine receptor M3 | GPCR | Ki | 5.85 | DRUG MATRIX | |||||
Beta-3 adrenergic receptor | GPCR | Ki | 5.50 | DRUG MATRIX | |||||
Alpha-2C adrenergic receptor | GPCR | Ki | 6.12 | DRUG MATRIX | |||||
Sodium-dependent dopamine transporter | Transporter | Ki | 5.69 | DRUG MATRIX | |||||
Adenosine receptor A3 | GPCR | Ki | 6.61 | DRUG MATRIX | |||||
Cytochrome P450 2C8 | Enzyme | Ki | 5.96 | WOMBAT-PK | |||||
Delta-type opioid receptor | GPCR | Ki | 5.77 | DRUG MATRIX | |||||
Arachidonate 5-lipoxygenase | Enzyme | Ki | 4.33 | WOMBAT-PK | |||||
Epidermal growth factor receptor | Kinase | IC50 | 5.50 | DRUG MATRIX | |||||
Tyrosine-protein kinase Fyn | Kinase | IC50 | 5.33 | DRUG MATRIX | |||||
Thromboxane-A synthase | Enzyme | IC50 | 5.82 | DRUG MATRIX | |||||
Cysteinyl leukotriene receptor 2 | GPCR | Ki | 5.30 | PDSP | |||||
Mitogen-activated protein kinase 14 | Kinase | IC50 | 6.07 | DRUG MATRIX | |||||
Substance-K receptor | GPCR | Ki | 5.90 | DRUG MATRIX | |||||
Uracil nucleotide/cysteinyl leukotriene receptor | GPCR | Ki | 5.18 | CHEMBL | |||||
Beta-2 adrenergic receptor | GPCR | Ki | 5.62 | DRUG MATRIX | |||||
Cysteinyl leukotriene receptor 1 | GPCR | Ki | 9.30 | CHEMBL | |||||
Uracil nucleotide/cysteinyl leukotriene receptor | GPCR | ANTAGONIST | IC50 | 7.21 | IUPHAR |
ID | Source |
---|---|
4024117 | VUID |
N0000022122 | NUI |
D00529 | KEGG_DRUG |
151767-02-1 | SECONDARY_CAS_RN |
4021110 | VANDF |
4024117 | VANDF |
C0298130 | UMLSCUI |
CHEBI:50730 | CHEBI |
MTK | PDB_CHEM_ID |
CHEMBL787 | ChEMBL_ID |
CHEMBL1200681 | ChEMBL_ID |
DB00471 | DRUGBANK_ID |
C093875 | MESH_SUPPLEMENTAL_RECORD_UI |
3340 | IUPHAR_LIGAND_ID |
7388 | INN_ID |
MHM278SD3E | UNII |
5281040 | PUBCHEM_CID |
115713 | RXNORM |
11578 | MMSL |
189710 | MMSL |
5134 | MMSL |
d04289 | MMSL |
007256 | NDDF |
007257 | NDDF |
108620002 | SNOMEDCT_US |
320883008 | SNOMEDCT_US |
373728005 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-7487 | GRANULE | 4 mg | ORAL | ANDA | 31 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-7487 | GRANULE | 4 mg | ORAL | ANDA | 31 sections |
MONTELUKAST | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9649 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 25 sections |
MONTELUKAST | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9650 | TABLET, CHEWABLE | 5 mg | ORAL | ANDA | 25 sections |
MONTELUKAST | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9651 | TABLET, CHEWABLE | 4 mg | ORAL | ANDA | 25 sections |
Montelukast | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-5554 | TABLET, CHEWABLE | 4 mg | ORAL | ANDA | 28 sections |
Montelukast | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-5555 | TABLET, CHEWABLE | 5 mg | ORAL | ANDA | 28 sections |
Montelukast | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-5560 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 28 sections |
Montelukast | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6808 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 28 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-079 | TABLET, CHEWABLE | 4 mg | ORAL | ANDA | 29 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-079 | TABLET, CHEWABLE | 4 mg | ORAL | ANDA | 29 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-079 | TABLET, CHEWABLE | 4 mg | ORAL | ANDA | 29 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-079 | TABLET, CHEWABLE | 4 mg | ORAL | ANDA | 29 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-080 | TABLET, CHEWABLE | 5 mg | ORAL | ANDA | 29 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-080 | TABLET, CHEWABLE | 5 mg | ORAL | ANDA | 29 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-080 | TABLET, CHEWABLE | 5 mg | ORAL | ANDA | 29 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-080 | TABLET, CHEWABLE | 5 mg | ORAL | ANDA | 29 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-081 | TABLET | 10 mg | ORAL | ANDA | 29 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-081 | TABLET | 10 mg | ORAL | ANDA | 29 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-081 | TABLET | 10 mg | ORAL | ANDA | 29 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-081 | TABLET | 10 mg | ORAL | ANDA | 29 sections |
MONTELUKAST SODIUM ORAL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-531 | GRANULE | 4 mg | ORAL | ANDA | 19 sections |
MONTELUKAST SODIUM ORAL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-531 | GRANULE | 4 mg | ORAL | ANDA | 19 sections |
MONTELUKAST SODIUM ORAL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-531 | GRANULE | 4 mg | ORAL | ANDA | 19 sections |
MONTELUKAST SODIUM ORAL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-531 | GRANULE | 4 mg | ORAL | ANDA | 19 sections |
MONTELUKAST SODIUM ORAL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-531 | GRANULE | 4 mg | ORAL | ANDA | 19 sections |
MONTELUKAST SODIUM | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16571-100 | TABLET | 10 mg | ORAL | ANDA | 20 sections |
Montelukast Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16729-119 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 28 sections |
SINGULAIR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-221 | TABLET, FILM COATED | 10 mg | ORAL | NDA | 28 sections |
SINGULAIR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-565 | TABLET, CHEWABLE | 5 mg | ORAL | NDA | 28 sections |