DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
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L1000
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
amitriptylinoxide 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
181
4317-14-0
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
amitriptylinoxide
amitriptyline N-oxide
amitriptyline oxide
Molecular weight: 293.41
Formula: C20H23NO
CLOGP: 2.22
LIPINSKI: 0
HAC: 2
HDO: 0
TPSA: 23.06
ALOGS: -6.02
ROTB: 3
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
4.84
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Proto-oncogene tyrosine-protein kinase receptor Ret
Kinase
P07949
RET_HUMAN
IC50
5
CHEMBL
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External reference:
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entries
Search:
ID
Source
006696
NDDF
20313
PUBCHEM_CID
236734
RXNORM
3926
INN_ID
C0051694
UMLSCUI
C006566
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:135224
CHEBI
CHEMBL627
ChEMBL_ID
D07449
KEGG_DRUG
DB13114
DRUGBANK_ID
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Pharmaceutical products:
None
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Structure 🔎
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amitriptylinoxide