metiazinic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1776 13993-65-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • metiazinic acid
  • metazionic acid
  • methiazic acid
  • methiazinic acid
  • metiazic acid
phenothiazine which acts as an anti-inflammatory agent; minor descriptor (75-86); on line & INDEX MEDICUS search PHENOTHIAZINES (75-86)
  • Molecular weight: 271.33
  • Formula: C15H13NO2S
  • CLOGP: 3.60
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 40.54
  • ALOGS: -3.90
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:35475 non-steroidal anti-inflammatory agent
CHEBI has role CHEBI:88188 allergenic drug

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.48 acidic
pKa2 5.1 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Prostaglandin G/H synthase 2 Enzyme IC50 4.98 CHEMBL

External reference:

IDSource
D01189 KEGG_DRUG
C0066452 UMLSCUI
CHEBI:31838 CHEBI
CHEMBL2105269 ChEMBL_ID
C100259 MESH_SUPPLEMENTAL_RECORD_UI
4164 PUBCHEM_CID
2519 INN_ID
12I0HHE2ZY UNII

Pharmaceutical products:

None