methoxyphenamine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
bronchodilators, phenethylamine derivatives 1755 93-30-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • methoxyphenamine
  • methoxiphenadrin
  • 2-Methoxymethamphetamine
  • methoxyphenadrine
  • methoxyphenamin
  • orthoxine
  • ortodrinex
  • ortoxine
  • methoxyphenamine hydrochloride
  • methoxyphenamine HCl
  • Molecular weight: 179.26
  • Formula: C11H17NO
  • CLOGP: 1.81
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 1
  • TPSA: 21.26
  • ALOGS: -2.36
  • ROTB: 4

Drug dosage:

DoseUnitRoute
0.40 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AKT1,AKT2,AKT3,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,ITK,JAK2,JAK3,MAP3K21,MAP3K7,MAPK12,MAPK7,MET,MTOR,NTRK2,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,ZAP70 44
kinase-selectivity-class AXL,BRAF,GRK2,PDK4,SIK2 5
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R03CB02 RESPIRATORY SYSTEM
DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
ADRENERGICS FOR SYSTEMIC USE
Non-selective beta-adrenoreceptor agonists
MeSH PA D000318 Adrenergic beta-Agonists
MeSH PA D000322 Adrenergic Agonists
MeSH PA D018377 Neurotransmitter Agents
MeSH PA D018663 Adrenergic Agents
CHEBI has role CHEBI:35522 β-adrenergic agonist
CHEBI has role CHEBI:35523 bronchodilator agent

Related Drugs by ATC class:

R03CB Non-selective beta-adrenoreceptor agonists 2 drugs
isoprenalineorciprenaline

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.99 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01635 KEGG_DRUG
C0066165 UMLSCUI
CHEBI:134817 CHEBI
CHEMBL2010507 ChEMBL_ID
DB13624 DRUGBANK_ID
CHEMBL1985928 ChEMBL_ID
4117 PUBCHEM_CID
137 INN_ID
C005157 MESH_SUPPLEMENTAL_RECORD_UI
5588-10-3 SECONDARY_CAS_RN
J3Z5SRI26Z UNII
29704 RXNORM
001799 NDDF
004724 NDDF
69351002 SNOMEDCT_US
708599005 SNOMEDCT_US

Pharmaceutical products:

None