menadione sodium bisulfite 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 1684 | 130-37-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000933 | Antifibrinolytic Agents |
| MeSH PA | D003029 | Coagulants |
| MeSH PA | D006401 | Hematologic Agents |
| MeSH PA | D006490 | Hemostatics |
| MeSH PA | D018977 | Micronutrients |
| MeSH PA | D014815 | Vitamins |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 2.82 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Aldose reductase | Enzyme | IC50 | 4.09 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| 6XF3C2HK77 | UNII |
| D08177 | KEGG_DRUG |
| C0127516 | UMLSCUI |
| CHEBI:63928 | CHEBI |
| CHEMBL2107211 | ChEMBL_ID |
| 23665888 | PUBCHEM_CID |
| D024483 | MESH_DESCRIPTOR_UI |
| 52551 | RXNORM |
| 001041 | NDDF |
| 708600008 | SNOMEDCT_US |
| DB15944 | DRUGBANK_ID |
| 6147-37-1 | SECONDARY_CAS_RN |
Pharmaceutical products:
None