methyl aminolevulinate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
168 33320-16-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • aminolevulinic acid methyl ester
  • 5-Amino-4-oxopentanoic acid methyl ester
  • methyl aminolevulinate
  • methyl aminolevulinate hydrochloride
  • methyl aminolevulinate HCl
  • Molecular weight: 145.16
  • Formula: C6H11NO3
  • CLOGP: -0.67
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 69.39
  • ALOGS: 0.18
  • ROTB: 5

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
July 27, 2004 FDA GALDERMA LABS LP

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC L01XD03 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
ANTINEOPLASTIC AGENTS
OTHER ANTINEOPLASTIC AGENTS
Sensitizers used in photodynamic/radiation therapy
FDA CS M0017335 Porphyrinogens
FDA EPC N0000175846 Porphyrin Precursor
CHEBI has role CHEBI:35610 antineoplastic agents
CHEBI has role CHEBI:47868 photosensitising agent
CHEBI has role CHEBI:50177 dermatologic agent
CHEBI has role CHEBI:50266 Prodrugs

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Non-Hyperkeratotic Actinic Keratoses indication
Photosensitivity contraindication 90128006




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.43 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4028718 VUID
N0000178414 NUI
D04988 KEGG_DRUG
1300479 RXNORM
C1134467 UMLSCUI
CHEBI:724125 CHEBI
CHEMBL1096562 ChEMBL_ID
DB00992 DRUGBANK_ID
C114767 MESH_SUPPLEMENTAL_RECORD_UI
79416-27-6 SECONDARY_CAS_RN
585NM85KYM UNII
157922 PUBCHEM_CID
25794 MMSL
009997 NDDF
009998 NDDF
4028718 VANDF
CHEMBL1201093 ChEMBL_ID
409397005 SNOMEDCT_US
439082000 SNOMEDCT_US

Pharmaceutical products:

None