methyl aminolevulinate Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
168 33320-16-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • aminolevulinic acid methyl ester
  • 5-Amino-4-oxopentanoic acid methyl ester
  • methyl aminolevulinate
  • methyl aminolevulinate hydrochloride
  • methyl aminolevulinate HCl
  • Molecular weight: 145.16
  • Formula: C6H11NO3
  • CLOGP: -0.67
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 69.39
  • ALOGS: 0.18
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
July 27, 2004 FDA GALDERMA LABS LP

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC L01XD03 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
ANTINEOPLASTIC AGENTS
OTHER ANTINEOPLASTIC AGENTS
Sensitizers used in photodynamic/radiation therapy
FDA CS M0017335 Porphyrinogens
FDA EPC N0000175846 Porphyrin Precursor
CHEBI has role CHEBI:35610 cytostatic
CHEBI has role CHEBI:47868 photosensitising agent
CHEBI has role CHEBI:50177 dermatological agent
CHEBI has role CHEBI:50266 prodrugs

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Non-Hyperkeratotic Actinic Keratoses indication
Photosensitivity contraindication 90128006

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.43 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4028718 VUID
N0000178414 NUI
D04988 KEGG_DRUG
79416-27-6 SECONDARY_CAS_RN
C2350728 UMLSCUI
CHEBI:724125 CHEBI
CHEMBL1096562 ChEMBL_ID
DB00992 DRUGBANK_ID
CHEMBL1201093 ChEMBL_ID
157922 PUBCHEM_CID
C114767 MESH_SUPPLEMENTAL_RECORD_UI
585NM85KYM UNII
1300479 RXNORM
25794 MMSL
009997 NDDF
009998 NDDF
409397005 SNOMEDCT_US
439082000 SNOMEDCT_US
4028718 VANDF

Pharmaceutical products:

None