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methyl aminolevulinate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 168 | 33320-16-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,AKT2,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,IGF1R,ITK,JAK2,JAK3,MAP2K6,MAP3K21,MAP3K7,MAPK7,MAPK9,MAPKAPK2,MET,MTOR,NTRK2,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ZAP70 | 49 | |||
| kinase-selectivity-class | AXL,BRAF,EPHB4,GRK2,MAP2K6,MAPK7,STK33,TEK | 8 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| July 27, 2004 | FDA | GALDERMA LABS LP |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | L01XD03 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS ANTINEOPLASTIC AGENTS OTHER ANTINEOPLASTIC AGENTS Sensitizers used in photodynamic/radiation therapy |
| FDA CS | M0017335 | Porphyrinogens |
| FDA EPC | N0000175846 | Porphyrin Precursor |
| CHEBI has role | CHEBI:35480 | analgesic |
| CHEBI has role | CHEBI:35610 | antineoplastic agent |
Related Drugs by ATC class:
L01XD Sensitizers used in photodynamic/radiation therapy 5 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Non-Hyperkeratotic Actinic Keratoses | indication | ||
| Photosensitivity | contraindication | 90128006 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 9.43 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4028718 | VUID |
| N0000178414 | NUI |
| D04988 | KEGG_DRUG |
| 1300479 | RXNORM |
| C1134467 | UMLSCUI |
| CHEBI:724125 | CHEBI |
| CHEMBL1096562 | ChEMBL_ID |
| CHEMBL1201093 | ChEMBL_ID |
| DB00992 | DRUGBANK_ID |
| C114767 | MESH_SUPPLEMENTAL_RECORD_UI |
| 79416-27-6 | SECONDARY_CAS_RN |
| 585NM85KYM | UNII |
| 157922 | PUBCHEM_CID |
| 25794 | MMSL |
| 4028718 | VANDF |
| 009997 | NDDF |
| 009998 | NDDF |
| 409397005 | SNOMEDCT_US |
| 439082000 | SNOMEDCT_US |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| KRX Aesthetics PD-13 Therapy | HUMAN OTC DRUG LABEL | 1 | 84755-0010 | SPRAY | 1.95 mg | TOPICAL | unapproved drug other | 8 sections |
| KRX Aesthetics PD-13 Therapy | HUMAN OTC DRUG LABEL | 1 | 87565-0010 | SPRAY | 1.95 mg | TOPICAL | unapproved drug other | 8 sections |