levamfetamine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1562 156-34-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • levamphetamine
  • levoamphetamine
  • R-Amphetamine
  • L-Amphetamine
  • levamfetamine
  • levamfetamine succinate
  • Molecular weight: 135.21
  • Formula: C9H13N
  • CLOGP: 1.74
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 1
  • TPSA: 26.02
  • ALOGS: -1.89
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.89 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Trace amine-associated receptor 1 GPCR EC50 6.60 CHEMBL
Sigma non-opioid intracellular receptor 1 Membrane receptor Ki 4.33 CHEMBL
Trace amine-associated receptor 1 GPCR EC50 7.47 CHEMBL
Trace amine-associated receptor 1 GPCR EC50 7.19 CHEMBL
Serotonin (5-HT) receptor GPCR Kd 5.16 CHEMBL
Trace amine-associated receptor 1 GPCR EC50 5.73 CHEMBL

External reference:

IDSource
D04704 KEGG_DRUG
85242006 SNOMEDCT_US
32893 PUBCHEM_CID
CHEBI:42724 CHEBI
CHEMBL19393 ChEMBL_ID
R87US8P740 UNII
1313 INN_ID
5634-40-2 SECONDARY_CAS_RN
CHEMBL2106371 ChEMBL_ID

Pharmaceutical products:

None