itopride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| sulpiride derivatives and analogues | 1512 | 122898-67-3 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 0.15 | g | O |
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Trimethylaminuria | 153.57 | 56.00 | 19 | 783 | 154 | 63488066 |
| Pseudomembranous colitis | 98.70 | 56.00 | 19 | 783 | 3093 | 63485127 |
| Peritonitis | 89.55 | 56.00 | 24 | 778 | 17130 | 63471090 |
| Megacolon | 88.10 | 56.00 | 16 | 786 | 1899 | 63486321 |
| Dysbiosis | 78.58 | 56.00 | 13 | 789 | 893 | 63487327 |
| Intestinal perforation | 73.22 | 56.00 | 19 | 783 | 11944 | 63476276 |
| Drug interaction | 66.15 | 56.00 | 39 | 763 | 229092 | 63259128 |
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Trimethylaminuria | 158.02 | 37.37 | 20 | 1099 | 176 | 79743093 |
| Pseudomembranous colitis | 91.87 | 37.37 | 20 | 1099 | 5354 | 79737915 |
| Megacolon | 82.60 | 37.37 | 17 | 1102 | 3478 | 79739791 |
| Dysbiosis | 80.01 | 37.37 | 14 | 1105 | 1205 | 79742064 |
| Peritonitis | 79.46 | 37.37 | 25 | 1094 | 28011 | 79715258 |
| Intestinal perforation | 68.50 | 37.37 | 20 | 1099 | 17406 | 79725863 |
| Inhibitory drug interaction | 45.99 | 37.37 | 11 | 1108 | 4442 | 79738827 |
| Drug interaction | 45.39 | 37.37 | 41 | 1078 | 415142 | 79328127 |
| Clostridium difficile infection | 43.99 | 37.37 | 18 | 1101 | 42667 | 79700602 |
| Breath odour | 38.59 | 37.37 | 8 | 1111 | 1688 | 79741581 |
| White blood cells urine positive | 37.78 | 37.37 | 10 | 1109 | 6065 | 79737204 |
| Urine odour abnormal | 37.46 | 37.37 | 10 | 1109 | 6263 | 79737006 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A03FA07 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS PROPULSIVES Propulsives |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Chronic gastritis | indication | 8493009 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.61 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D02729 | KEGG_DRUG |
| 122892-31-3 | SECONDARY_CAS_RN |
| C0531483 | UMLSCUI |
| CHEBI:94809 | CHEBI |
| CHEMBL2107457 | ChEMBL_ID |
| DB04924 | DRUGBANK_ID |
| C102254 | MESH_SUPPLEMENTAL_RECORD_UI |
| 3792 | PUBCHEM_CID |
| 6879 | INN_ID |
| 81BMQ80QRL | UNII |
| 017624 | NDDF |
| 017625 | NDDF |
| 1217454005 | SNOMEDCT_US |
| 20691000122100 | SNOMEDCT_US |
Pharmaceutical products:
None