isometheptene 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1496 503-01-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • isometheptene
  • isomethepten
  • octinum
  • 6-Methylamino-2-methylheptene
  • isometheptene mucate
  • isometeptene
  • Molecular weight: 141.26
  • Formula: C9H19N
  • CLOGP: 2.35
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 1
  • TPSA: 12.03
  • ALOGS: -1.66
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A03AX10 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Other drugs for functional gastrointestinal disorders

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Migraine off-label use 37796009 DOID:6364
Vascular headache off-label use 128187005
Tension-type headache off-label use 398057008
Necrotizing enterocolitis in fetus OR newborn contraindication 2707005
Alcoholism contraindication 7200002
Peptic ulcer contraindication 13200003 DOID:750
Glaucoma contraindication 23986001 DOID:1686
Acute cerebrovascular insufficiency contraindication 29322000
Hypertensive disorder contraindication 38341003 DOID:10763
Conduction disorder of the heart contraindication 44808001
Acute nephropathy contraindication 58574008
Hepatic failure contraindication 59927004
Poisoning by acetaminophen contraindication 70273001
Agoraphobia contraindication 70691001 DOID:593
Seizure disorder contraindication 128613002
Obsessive-compulsive disorder contraindication 191736004 DOID:10933
Insomnia contraindication 193462001
Impaired renal function disorder contraindication 197663003
Disease of liver contraindication 235856003 DOID:409
Panic disorder contraindication 371631005 DOID:594
Peripheral vascular disease contraindication 400047006
Myocardial ischemia contraindication 414795007 DOID:3393
Myocardial infarction in recovery phase contraindication 418044006
Organic Cardiac Disease contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.72 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07097 KEGG_DRUG
7492-31-1 SECONDARY_CAS_RN
4018809 VANDF
C0064007 UMLSCUI
CHEBI:134765 CHEBI
CHEMBL1697841 ChEMBL_ID
DB06706 DRUGBANK_ID
CHEMBL2355839 ChEMBL_ID
22297 PUBCHEM_CID
576 INN_ID
C008192 MESH_SUPPLEMENTAL_RECORD_UI
Y7L24THH6T UNII
104994 RXNORM
4928 MMSL
d03077 MMSL
001759 NDDF
001762 NDDF
116516007 SNOMEDCT_US
387302004 SNOMEDCT_US
54824008 SNOMEDCT_US

Pharmaceutical products:

None